Báo cáo y học: "Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis." pdf

... 2008) doi:10.1111/j.1742-4658.2008.06347.x Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional ... ARTICLE Chemical approaches to mapping the function of post-translational modifications David P. Gamblin, Sander...

Ngày tải lên: 18/02/2014, 17:20

... with induced expression of insulin-like growth factor binding protein-2 in the uterus and ovary and decreased expression of insulin- like growth factor binding protein-3 in the uterus. These changes ... biosynthesis, as DFMO retards the growth of the pancreas [101], but does not inhibit the secretory function of the exocrine part of the organ [102]. The cellular...

Ngày tải lên: 30/03/2014, 13:20

... uniquely expressed genes. Selection of hypervariable (HV) genes To have an opportunity to evaluate inhomogeneity in gene expression variability, it is necessary to normalize this vari- ability to ... article Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis James N Jarvis* 1 , Igor Dozmorov* 2 , Kaiyu Jiang 1 ,...

Ngày tải lên: 09/08/2014, 01:23

... novice to expert: agroecological competences of children orphaned by AIDS compared to non-orphans in Benin. Journal of Ethnobiology and Ethnomedicine 2011 7:4. Fagbemissi and Price Journal of Ethnobiology ... and children in relationship to being affected by AIDS in the Couffo region of Benin are documented. Complementing an earlier s tudy which e...

Ngày tải lên: 10/08/2014, 09:21

... Th1). The motor fiber of the median nerve originates from two sep- arate cervical roots (C8, Th1) in much the same way as the ulnar nerve, so in order to analyse the DCH, we consid- ered the motor ... measuring the peak to peak of the M-wave. Motor distal latency (MDL) was obtained from the onset latency of the M-wave. The latency between the ante...

Ngày tải lên: 10/08/2014, 10:20

... Nakagawa M, Kinoshita M, Kawai C: Long-term prognosis after myocardial infarction: univariate and multivariate analysis of clinical characteristics in 1,000 patients. Kyoto and Shiga Myocardial ... related to myocardial infarction and cardiovascular outcome: a retrospective observational study Roland von Känel 1,2* , Roman Hari 1 , Jean-Paul Schmid 2 , Hugo Saner...

Ngày tải lên: 11/08/2014, 15:22

... Alternative way to test the efficacy of swine FMD vaccines: measurement of pigs median infected dose (PID 50 ) and regulation of live virus challenge dose. Virology Journal 2010 7:215. Table 2 The results ... is the leader of the study group. DL carried out the experiments and wrote the manuscript. ZJL and PS carried out the animal...

Ngày tải lên: 12/08/2014, 01:21

... to improved control of disease activity. Thus, therapeutic drug monitoring of infliximab may improve the control of disease activity in RA. Competing interests DM and J-PV took part in clinical trials ... infliximab concentration. Therapeutic drug moni- toring of infliximab could result in a lowering of dosage in patients having higher exposure than needed,...

Ngày tải lên: 12/08/2014, 11:22

... of genomics in lung cancer research In the next few years, a considerable effort will be made to classify lung cancers, to discover genes involved in lung cancer pathogenesis, and to study the ... cell carcinoma in the evaluation of a lung tumor. However, our inability to subclassify lung cancer further is not frequently recognized as a critical deficiency. M...

Ngày tải lên: 12/08/2014, 18:20

... 1998, 52:44–49. Respiratory Research Vol 2 No 4 Geraci et al Available online http://respiratory -research. com/content/2/4/210 commentary review reports primary research factors, inflammatory mediators, or ... chronic hypobaric hypoxia. We conclude that PGIS plays a major role in modifying the pulmonary vascular response to chronic hypoxia. Additional data investigating the prosta...

Ngày tải lên: 12/08/2014, 18:20

... delivered directly into the airways, can be transformed by esterase cleavage into the active metabolite (R-M1) producing high local anti -inflammatory activity. The anti -inflammatory effi- cacy of Ciclesonide ... release, providing further evidence of the potential beneficial effects of these type of compounds in the treat- ment of inflammatory diseases of the a...

Ngày tải lên: 12/08/2014, 18:20

... cells of this sample was puromycin resist- ant. An example of the calculation to estimate the proportion of cells resistant to puromycinFigure 4 An example of the calculation to estimate the proportion ... (5'- gccactccccagtccgccc-3'). The primers used to detect the ampicillin resistant gene are AmpF (5'-gataacactgcg- gccaactt-3') and...

Ngày tải lên: 13/08/2014, 09:20

... most abundant topology, followed by Lys63 and Lys11 chains and the less frequent linkages through Lys33, Lys27, Lys6, and Lys29 (the latter is detected only in combination with Lys33 linkage) ... ubiquitin-proteasome system has started to attract global approaches that are beginning to make important contribu- tions to our understanding of the system. Chemistry-based approaches...

Ngày tải lên: 14/08/2014, 14:22

... sensitive to the actions of the drug; (3) enzymatic destruction or modification of the drug either in the cytoplasm, for example, the inactivation of gentamicin by aminoglycoside-modifying enzymes, ... removal of drugs from the periplasm or cytoplasm by efflux pumps. In some cases, drug resistance is due to a combination of these mechanisms. Drugs Porin Drug target Periplasm Cell...

Ngày tải lên: 14/08/2014, 16:20

... Genome Biology 2008, 9:R181 Open Access 2008Maet al.Volume 9, Issue 12, Article R181 Research Male reproductive development: gene expression profiling of maize anther and pollen ontogeny Jiong Ma Ô , ... meiosis and later pollen dispersal. Synchronous development of many anthers per tassel and within each anther facilitates dissection of carefully staged mai...

Ngày tải lên: 14/08/2014, 21:20