Báo cáo y học: "α Interpreting interest in interferon-α" pdf

... is likely to be the main cytokine contributing to this defect. Viewpoint Interpreting interest in interferon- αα Donna L Thibault and Paul J Utz Division of Immunology and Rheumatology, Department ... uncertain, although cytokines are believed to play an important role. The group of cytokines known as interferons was first characterized in 1957. Interferons were named for their abilit...

Ngày tải lên: 09/08/2014, 01:23

... inflammatory protein [MIP]-1, DN = double negative; H & E = hematoxylin and eosin; IFN = interferon; IL = interleukin; IP-10 = interferon-γ-inducible protein 10; MIP = macrophage inflammatory protein; ... difference. Results Evaluation of pulmonary inflammation and phenotype analyses of infiltrating cells in lung We first examined the development of pulmonary inflamma- tion in MRL/lpr...

Ngày tải lên: 09/08/2014, 01:23

... and/or retention in the synovial joint. Alternatively, IFN-β may inhibit inflammatory cell infiltration indirectly, via suppression of FLS and/or monocyte activation. Our data demonstrated statistically significant modulation ... receptor antibody may be effective in RA patients [37]. Of interest, IL-10 production was increased in the IFN-β-treated animals. IL-10 may be a potent anti-...

Ngày tải lên: 09/08/2014, 01:23

... peripheral blood or synovial fluid lymphocytes induced TNF production by monocytic cells within 24 hours, an effect that was mainly mediated by NK cells. In turn, monocytic cells induced CD69 expression ... receptor molecules involved in inducing the secretion of TNF by monocytic cells in vitro. The TNF secreted by monocytic cells was measured when they were co-cultured with either rest...

Ngày tải lên: 09/08/2014, 08:22

... planning, teaching and training responsibilities offers possibilities for planning, teaching and training disaster medicine by giving immediate feed- back based on real incidents. Background Introduction To ... be included in the risk assessment regarding possible major incidents in this region. The purpose of this study was to find whether this institution has achieved its primary tasks...

Ngày tải lên: 25/10/2012, 09:56

... family history, ethnicity, increasing age, central obesity, physical inactivity, low HDL/high triglycerides, fasting glucose of 110 mg/dL or greater, gestational diabe- tes, hypertension, and polycystic ... Angiotensin Converting Enzyme CYP = Cytochrome P450 + Not all agents are appropriate for monotherapy. Inclusion in this table does not necessarily imply efficacy. * Currently FDA approv...

Ngày tải lên: 25/10/2012, 10:51

... craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI. 2-8 Presently, th e European Brain Injury Consortium and Brain Trauma ... Nerv Syst 2005;21:1014-1015. 48. Taylor A, Butt W, Rosenfeld J, et al. A randomized trial of very early decompressive craniectomy in children with traumatic brain injury and susta...

Ngày tải lên: 25/10/2012, 11:40

... a large number of different binding molecules. Espe- cially fibrinogen, extracellular matrix proteins and glycosaminoglycans, including fibronectin and laminin, are components of the blood ... Teicoplanin and Vancomycin are used. Ex- tending this repertoire with newer antibiotics, espe- cially Linezolid, Daptomycin and Tigecyclin were introduced for PJI therapy. A valid rating for ... 23...

Ngày tải lên: 26/10/2012, 09:57

... common polymorphisms in DNA repair genes are continuously being identified, and these polymorphisms may play a pivotal role in sporadic carcinogenesis. A growing body of literature, including observations ... important for maintaining DNA integrity and preventing carcinogenesis. Recent lung cancer studies have focused on identifying the effects of single nucleotide polymorphisms (SNP...

Ngày tải lên: 31/10/2012, 14:59

... following lengthy incubation periods. However, synthetic prions were not able to transmit disease directly to wild type mice. To obtain infectivity in wild type mice, synthetic prions were Int. ... produc- ing infectious amyloid fibrils, infectivity remained the most controversial characteristic of the amyloid fibrils generated by this assay. Prusiner and colleagues in- duced amyloi...

Ngày tải lên: 03/11/2012, 11:52