Báo cáo y học: "Prevalence, clinical relevance and characterization of circulating cytotoxic CD4+CD28– T cells in ankylosing spondylitis" ppt

... peptides to CD8 + T lymphocytes in the pres- ence of β 2 -microglobulin [1,2], and much work has concentrated on characterizing B27 restricted cytotoxic T lymphocytes in spondyloarthropathy patients ... & Therapy Vol 5 No 5 Duftner et al. Research article Prevalence, clinical relevance and characterization of circulating cytotoxic CD4 + CD28 – T cells in...

Ngày tải lên: 09/08/2014, 01:23

... 134 ccttgtctagGCATT TCTACgtgagtctct 4 761 0 Human 4 134 cctggcccagGAGTT TCTACgtgagtccgg 4 >2147 c 0 Mouse 5 165 ttgtgctcagGTTAC ACCAGgtgagtcatt 5 945 0 Human 5 165 atgtgctcagTTCAC ATCAGgtgagccttt ... 180 ccgacctcagGCCTC CATAGgtgacacctc 9 145 1 Mouse 10 117 ctctttgcagGTTGG GTTTGgtaagtatct 10 681 1 Human 10 114/126 d cttgtttcagGTCGC GTTGGgtgatctcaa 10 801 1 Mouse 11 120 ttcttcacagATGAG GCCCG...

Ngày tải lên: 08/03/2014, 23:20

... compared with other patients with SSc, patients with primary Raynaud’s phe- nomenon and patients with other CTD [22,23]. One must be very cautious of the specificity of this type of testing, although ... [10]. The specificity and sensitivity of ANA vary depending on the antigen substrate used for the assay. The use of HEp2 cells yields a better sensitivity for the detection o...

Ngày tải lên: 09/08/2014, 01:21

... activity is mostly due to its capacity to inhibit the entry of HIV-1 into T cells and may limit the reverse transcription step into macrophages and DC. These findings indicate that C14 harbours potent ... data strongly suggest that C14 could alter the infectiousness of viruses, inhibiting the entry of viruses into T cells and interfering with the HIV-1 reverse transcriptas...

Ngày tải lên: 10/08/2014, 05:21

... guidelines) than pilot sites embedded within com- munity hospitals that are dominant within their local markets. This hypothesis recognizes both the important influence of the community hospital setting ... engaged in the initial phases of its implementation, assessing and defining the innovation within the cultural context of the implementing organization, developing infrastructure...

Ngày tải lên: 11/08/2014, 05:21

... measurement. Determination of binding constants from forward scattering The intensity of Ôforward scatteringÕ,orI(0), is the X-ray solution scattering that is parallel to the incident beam, and was determined ... but produce very little change in arrestin’s solution structure and conformation. In summary, the transition in arrestin from a ÔbasalÕ state to an ÔactivatedÕ state th...

Ngày tải lên: 22/02/2014, 07:20

... magnitude of the accompanying enthalpy. The ratio o f the van t Hoff enthalpy to calorimetric enthalpy of 0.39 indicates that the nine putative segments of the coiled-coil domain of fibritin B1 ... 1-mm path length. CD data were analysed using the CONTIN program [20]. RESULTS Engineering and properties of fibritin deletion mutants To investigate the stability and thermodynamic pr...

Ngày tải lên: 24/03/2014, 03:21

... cellooligosaccharides and p-nitrophenyl b-glucopyranoside. Subsite stucture of the active center For determination of the active center subsite structure the kinetic parameters K m and V max of the hydrolytic ... rate constant K int . Accordingly, the substrate binding affinity becomes the sum of the affinities for glucose residues of the substrate accessible for binding; the dist...

Ngày tải lên: 24/03/2014, 04:21

... alter- native practices that may hinder early intervention. Another interesting finding of this study was that the more apt the healthcare workers were at being able to rec- ognize the symptoms of childhood ... authors declare that they have no competing interests. Authors' contributions All authors contributed to the conception of the study. MOB was involved with writing the initi...

Ngày tải lên: 08/08/2014, 23:21

... separately. Gen der and chron icity were ad ded to the model since they were found to pre- dict risk of relapse (not differential by treatment) in the original study [29]. Two-sided statistical tests ... Fluoxetine treatment during continuation and maintenance treatment was associated with continued remission (ratio of relapse hazard during placebo substitution to relapse hazard dur...

Ngày tải lên: 08/08/2014, 23:21