Báo cáo y học: "Higher susceptibility to Fas ligand induced apoptosis and altered α modulation of cell death by tumor necrosis factor-α in periarticular tenocytes from patients with knee joint osteoarthritis" ppt

... article Higher susceptibility to Fas ligand induced apoptosis and altered modulation of cell death by tumor necrosis factor- α in periarticular tenocytes from patients with knee joint osteoarthritis Andreas ... receptor I were measured using ELISA. Apoptosis was induced with recombinant human Fas ligand and measured by a histone fra...

Ngày tải lên: 09/08/2014, 01:23

... effect of CS inhalation on AM apoptosis. Caspases contribute to apoptosis through disassembly of cell structures by disrupting the nuclear structure and also by cleaving several cytoskeletal proteins ... evidenced by inflammation and increased air space, was assessed by histology and morphometric analysis. Protein oxidation was measured through oxyblot analysis of...

Ngày tải lên: 11/08/2014, 08:21

... function of the immune system. For instance, Ehlting and colleagues [12] recently reported that the regulation of a suppressor of cytokine signalling 3' (SOCS3) mRNA stability by tumor necrosis ... performance of B10.Q mice. Interestingly, the increased incidence and severity are pronounced traits in het- erozygous mice only, and the influence of the congenic frag...

Ngày tải lên: 09/08/2014, 10:23

... analyses, especially blinding of the person(s) making the decisions to the instruments being studied and to the objective of the study in general. From several studies in the literature, there is currently no evidence ... of RA activity by the clinician. When measures are integrated to yield pooled indices, the question slightly shifts toward how much the composite numbe...

Ngày tải lên: 09/08/2014, 07:20

... The obtained specimens were fixed in formalde- hyde. Immunohistology The fixed biopsies were embedded in paraffin, stained with Masson's trichrome and hematoxylin-eosin and examined by light ... computed tomography image interpretation The scans were evaluated by two independent radiologists blinded to clinical data coronary angiography and biopsy results in a joint...

Ngày tải lên: 10/08/2014, 10:20

... interferon- a -induced apoptosis [3] and both rat intestinal epithe- lial cells and HT-29 cells from transforming growth factor-b (TGFb)- and paclitaxel -induced apoptosis [4]. Keywords apoptosis; carbonic ... survival factor, protecting cells from apoptosis induced by a variety of agents. To determine if Evi1 also protects Rat1 cells from apoptosis, we treated o...

Ngày tải lên: 29/03/2014, 08:20

... role in decision-making by patients, by their health care providers and by regulatory authorities. Risk is inherent to essentially all drug therapy. Any pharmacological therapy is likely to have ... serious events may play a role in decision-making by patients, by their health care providers and by regulatory authorities. It is critical that serious drug toxicity be...

Ngày tải lên: 09/08/2014, 07:20

... modification, and that this may alter its activity. The possible role played by IL-1F5 therefore remains unknown. Investigation by RT-PCR of their expression in joints of mice with CIA and in synovial ... production of inflammatory mediators by synovial fibroblasts and articular chondrocytes David Magne 1 *, Gaby Palmer 1 *, Jenny L Barton 3 , Francoise Mézin 1 , Dom...

Ngày tải lên: 09/08/2014, 08:22

... reductions in activation of TP and MG. It is plausible that in redu- cing activity of TP and MG, tape may assist the resolu- tion of symptoms and restoration of function by unloading symptomatic ... that may occur with activity such as walking may result in injury to these soft tissues, the tibial fascia and/ or its insertion into the medial tibial crest. In our s...

Ngày tải lên: 10/08/2014, 21:24

... keep in mind when reading a mortality survey to determine the validity of the study and the applicability of the findings to their settings. Public health scenario You are a physician working ... how many people. In particular, we are interested in the total number of excess deaths. Investigators compute excess death tolls by multiplying the observed excess mortality rat...

Ngày tải lên: 25/10/2012, 10:31