Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx

... transfer to synoviocytes and osteoclasts. J Clin Invest 1999, 104:137-146. 14. Pap T, Franz JK, Hummel KM, Jeisy E, Gay RE, Gay S: Activation of synovial fibroblasts in rheumatoid arthritis: lack ... cultured rheumatoid synoviocytes. J Rheumatol 1995, 22:817-828. 12. Morel JC, Park CC, Zhu K, Kumar P, Ruth JH, Koch AE: Signal transduction pathways involved in rheumatoid arthritis s...

Ngày tải lên: 09/08/2014, 01:22

... shared-epitope genotypes for rheumatoid arthritis. Am J Hum Genet 1996, 58:371-383. 23. Kochi Y, Yamada R, Kobayashi K, Takahashi A, Suzuki A, Sekine A, Mabuchi A, Akiyama F, Tsunoda T, Nakamura Y, Yamamoto ... susceptibility for S 2 and S 3P alleles and an overall negative association with RA susceptibility for S 1 and X alleles. The genotype analysis performed in the present s...

Ngày tải lên: 09/08/2014, 10:23

... assay Previous kinetic studies on ODCs were performed either discontinuously by monitoring the decarboxyl- ation of oxalyl CoA to formyl CoA by HPLC and capillary electrophoresis, respectively ... respectively [17,18], or contin- uously by using two auxiliary enzymes, formate dehy- drogenase and formyl CoA transferase [2]. Here, a kinetic assay was established to directly monitor changes in t...

Ngày tải lên: 06/03/2014, 11:20

... discov- ery mode to optimize for glycopeptide detection. For the heavy chain, four distinct sets of glycopeptides were detected, corresponding to glycoforms of tryptic peptides carrying the N-glycosylated ... Man 5 GlcNAc 2 structure could only be identified on Asn183. For the light chains, tryptic glycopeptides carrying a single N-glycosylation site could be identified. Notably, the glyc...

Ngày tải lên: 07/03/2014, 06:20

... tetramethylrosamine; Rh I, tetramethylrhodamine ethyl ester or rhodamine I; Rh II, tetramethylrhodamine methyl ester or rhodamine II; Rh 123 hyd , hydrolysis product of Rh 123; RhI,II hyd , hydrolysis ... 123 hyd , the hydrolysis product of Rh123, was obtained by basic hydrolysis. The basic hydrolysis of RhI and RhII yielded the same compound that will be hereafter named RhI,II hyd . Stock so...

Ngày tải lên: 08/03/2014, 08:20

... five cycles of 94 °C for 30 s and 72 °C for 2 min, five cycles of 94 °C for 30 s, 70 °C for 30 s and 72 °C for 2 min, 25 cycles of 94 °C for 30 s, 68 °C for 30 s and 72 °C for 2 min, and 72 °C for ... neurosecretory systems containing putative moult-inhibiting hormone and hyperglycemic hormone in the eyestalk of brachyuran crustaceans. Cell Tissue Res 251, 3–12. 29 Ahyong ST &...

Ngày tải lên: 23/03/2014, 07:20

... normal y eye. (B) dFXRP(wild-type) overexpressed in y eye: note the rough eye phe- notype. (C) dFXRP(I307N) overexpressed in y eye: the effect on eye morphology is much less severe. (D–F) Cross-sections ... full-length proteins. Genotype vs. pheonotype in Fragile X syndrome I. Pozdnyakova and L. Regan 874 FEBS Journal 272 (2005) 872–878 ª 2005 FEBS New insights into Fragile X syndrome...

Ngày tải lên: 30/03/2014, 15:20

... cytolytic outcome to both cells types. More- over, the compromise of the skin-associated immune system is so critical that delayed-type hypersensitivity tests now commonly serve as monitors for ... features Hyperproliferation and hyperkeratosis, lymphocytic infiltrate and absence of granular layer Same [55] Presence of psoriatic arthritis 5-20% 23%-50% [54,55] Mean age of presentation >...

Ngày tải lên: 20/06/2014, 08:20

... Jan- uary 1994 to July 1995, he worked at Telecom Paris University. From October 1995 to May 2003, he was with Bel l Laboratories, Murray Hill, NJ, USA. In May 2003, he joined INRS-EMT, Uni- versity ... e(n)attimen as fol- lows: e(n) = y( n) − ˆ y( n), (1) where y( n) = h T t x(n)+w(n)(2) is the system output, h t =  h t,0 h t,1 ··· h t,L−1  T (3) New Insights into the RLS Algorithm...

Ngày tải lên: 23/06/2014, 01:20

... the WNK family, the gene for which is also transcribed rhythmically in Arabidopsis thaliana. Plant Cell Physiol 2002, 43:675-683. 51. Nakamichi N, Murakami-Kojima M, Sato E, Kishi Y, Yamashino T, Mizuno ... multiple physiological roles that can be geneti- cally separated. To date, the only defined activity within any region of the TOC1 polypeptide is a nuclear-trafficking signal estab- lis...

Ngày tải lên: 10/08/2014, 09:20