Báo cáo y học: "Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" potx

... days. The induction of arthritis by rHMGB1 is primarily mediated by IL-1 as confirmed by the absence of arthritis in IL-1 receptor-deficient mice after rHMGB1 administration [7]. Systemic administration ... administration of either neutralizing HMGB1 antigen-affinity purified polyclonal anti- bodies or the anti-inflammatory domain of HMGB1, termed the A-box protein, signif...

Ngày tải lên: 09/08/2014, 10:23

... mmHg of IAP. This might explain the absent effect of PEEP in reversing IAP induced FRC decline in the setting of grade IV IAH, respectively. However, we think this reduced influence of PEEP in ... did not increase the already high PaO 2 levels. InthepresenceofIAH,PEEPupto15cmH 2 Oonly partially reversed the IAP, induced FRC decline in grade II IAH, and did not incr...

Ngày tải lên: 13/08/2014, 21:20

... interferon-inducible gene expressions in peripheral blood mononuclear cells in vitro The expression of 15 IFI genes (IFIT1, IFIT3, IFIT5, IFI6, IFI16, IFI27, IFI30, IFI35, interferon-induced transmembrane ... of Figure 3 Effect of TNF stimulation on gene expression in healthy individuals and systemic lupus erythematosus patientsEffect of TNF stimulation on gene...

Ngày tải lên: 09/08/2014, 01:22

... IL-12 in system lupus erythematosus. II: IL-12 production in vitro is correlated nega- tively with serum IL-10, positively with serum IFN-gamma and negatively with disease activity in SLE. Cytokine ... cells in vitro The expression of 15 IFI genes (IFIT1, IFIT3, IFIT5, IFI6, IFI16, IFI27, IFI30, IFI35, interferon-induced transmembrane protein 1, ISG15, IRF7, OAS1, OASL, GBP1...

Ngày tải lên: 09/08/2014, 13:22

... because the sensitivity of in situ hybridization is lim- ited [50]. In the previous study, the synovial lining cells of RA patients were stained by the anti-IL-32 antibody [16]. We assumed that the ... syn- ovial lining cells by in situ hybridization in our study. Another explanation is the difference of types of RA. The distribution of IL-32 expression in sy...

Ngày tải lên: 09/08/2014, 08:23

... production of inflammatory cytokines and chemokines by HTLV -I- infected epithelial cells, in addition to that by infiltrating lymphocytes, may also play a role in the pathogenesis of HTLV -I- related ... infect primary rat retinal glial cells and induce gene expression of inflammatory cytokines. Curr Eye Res 1997, 16:782-791. 20. Miyoshi I, Kubonishi I, Yoshimoto S, Akagi...

Ngày tải lên: 13/08/2014, 05:21

... proliferation of infected cells and also inhibit apoptosis by their pleiotropic actions. Since the HTLV -I provirus is randomly integrated into the host genome, the identification of integration ... the increase of CD4-positive T-lymphocytes in vivo by enhanced proliferation and suppressed apoptosis. In HTLV -I- infected individuals, no virions are detected in the s...

Ngày tải lên: 13/08/2014, 09:21

... the 3 10 helix, stabilized by stacking interac- tions of the pyrrolidine ring of Pro7 with the aromatic side chain of Tyr137. Modelling of the PRD1-super peptide, which included two amino acid ... performed by the Src family kinase Fyn, which docks onto PAG using a dual-domain binding mode involving both SH3- and SH2-domains of Fyn. In this study, we investigated Fyn S...

Ngày tải lên: 24/03/2014, 00:21

... molecular modelling, which showed that all amino-acid residues involved in the catalytic activity of the A-chain and the sugar-binding activity in the B-chain are identical in both type- 2 RIPs. Expression of ... concerns their specific agglutination activity and the inhibition of agglutination by lactose and fetuin. In addition, both type- 2 RIPs exhibited the...

Ngày tải lên: 31/03/2014, 23:20

... variable, significant findings were found concerning the endogenous axis of DMS and the HDRS depressive index. The interaction of PD and DST produced significant findings concerning age, age of onset, ... University of Thesssaloniki, Greece, 2 Lab of Clin Neurophysiology, 1st Department of Neurology Aristotle University of Thesssaloniki, Greece and 3 Lab of Bioc...

Ngày tải lên: 08/08/2014, 20:23