Báo cáo y học: "Tissue engineering in the rheumatic diseases" ppsx
Báo cáo y học: "Tissue engineering in the rheumatic diseases" ppsx
... [12].Joint tissue engineering: clinical applications The first entry for the key word ‘tissue engineering , alsotermed ‘regenerative medicine’, in the National Center forBiotechnology Information ... [55].Cell sources for tissue engineering in rheumatic diseasesToday, autologous chondrocytes represent the only cell typeroutinely used for joint cartilage repair. In the future, autolo-gous or ... vigorous investigation.ReviewTissue engineering in the rheumatic diseasesJochen Ringe and Michael SittingerTissue Engineering Laboratory and Berlin-Brandenburg Center for Regenerative Therapies,...
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Báo cáo y học: "Gene therapy of the rheumatic diseases: 1998 to 2008" ppt
... Twoclinical trials exploring the use of gene therapy in OA areunder way and another is in the pipeline. If successful, theycould lead to wide human and veterinary application and pave the way ... as the Moloney murineleukemia virus, were the first to be used in clinical trials anddominated applications in human gene therapy for someyears, they are less popular now. Pseudotyping the ... early target forgene therapy (Figure 1), capturing the optimism of the early1990s and beginning clinical trials in 1996. The first Inter-national Meeting on the Gene Therapy of Arthritis andRelated...
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Báo cáo y học: "Outcome measures in inflammatory rheumatic diseases" pdf
... treatment in the inflammatory rheumatic diseasesnowadays has become reaching and sustaining remission.Clinical remission, meaning absence of clinically visibledisease manifestations, including the ... Heijde D, Bellamy N, Calin A, Dougados M, Khan MA, vander Linden S: Assessments in Ankylosing Spondylitis WorkingGroup. Preliminary core sets for endpoints in ankylosingspondylitis. J Rheumatol ... Relativerisks are easy to combine in meta-analyses.DeathMortality in RA was explored initially in 1953 and since thennumerous other studies have investigated mortality amongpatients with...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... bipolar disorder in the general population are likely receiving even less medicalcare. The significance of this finding is that the psychiatristmay be the only physician caring for these patients ... portacaval shunting, thereby decreasing first passmetabolism; decrease in quantities and affinity of plasmaproteins, thereby increasing free-drug levels; increase in volume of distribution in patients ... [57].Recognizing early symptoms of hepatic toxicity and dis-continuing treatment are important in optimizing recov-ery. Early symptoms of hepatic toxicity include apathy,malaise, fever, diminished...
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Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"
... continuously being identified, and these polymorphisms may play a pivotal role in sporadic carcinogenesis. A growing body of literature, including observations of inter-individual differences in ... also involved non-enzymatically in the subsequent 5' incision. It is further involved in the stabilization of a pre-incision complex on the damaged DNA. The ERCC5/XPG gene contains 17 ... located in the vicinity of the translation initiation codon, it may alter translation efficiency. The nearby proximal nucleo-tides to the AUG initiation codon are important for the initiation...
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Báo cáo Y học: Expression pattern in the antennae of a newly isolated lepidopteran Gq protein a subunit cDNA potx
... proposed to be the start of the proteincoding domain. Sequence analysis of the 3¢ end cDNArevealed that there is a polyadenylation signal upstream of the poly(A).Analysis of the primary structure ... T. & Hoshi, M. (1992) The primary structure of the alphasubunit of a starfish guanosine-nucleotide-binding regulatoryprotein involved in 1-methyladenine-induced oocyte maturation.Eur. J. ... 2002Recently, the a subunit of a G protein of the Gq familyhas been immunolocalized in olfactory sensilla preparationsof the silkmoth Antherea pernyi [23]. Using immunocytol-ogy, the authors...
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Báo cáo y học: "Treating rhinitis in the older population: special considerations" pdf
... mucous-secretingglands; the effectiveness of the mucociliary system isreduced, resulting in symptoms of nasal stuffiness. In addition, a decrease in nasal blood flow leads to atrophyand drying of the ... attention is paid in the general medical literature. In the most recently pub-lished highly regarded geriatric text, rhinitis is notincluded in the index whereas rhinophyma is [1]. The number of ... profuse rhinorrhea elicited byeating food, particularly highly seasoned foods. Cold airmay also be a trigger. Anticholinergic drugs may be useful in reducing the rhinorrhea of gustatory rhinitis....
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Báo cáo y học: "Physical anhedonia in the acute phase of schizophrenia" doc
... patients using the RPAS and the AIMS, the second using the PANSS and the EPSE and the third using the BARS. Information from the patient's his-tory, concerning social-demographic and clinical ... psychopathol-ogy symptoms, estimated by both the PANSS and the BPRS.We did not find any studies exploring the the relationshipbetween physical anhedonia and motor side effectsinduced by antipsychotic ... be independent todepression, to general psychopathology symptoms ormotor side-effects induced by antipsychotic agents.Regarding the relationship of physical anhedonia andnegative symptoms the...
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Báo cáo y học: "Chemokine receptors in the rheumatoid synovium: upregulation of CXCR" potx
... joints, and it results in the accumu-lation of leukocytes within the synovial tissue (ST) andsynovial fluid (SF). The inflammatory infiltrate consists pre-dominantly of B lymphocytes, T lymphocytes ... are another cell type expressing CXCR5 in the synovium. There have been several reports ofendothelial cells in the RA synovium expressing chemokinereceptors, including CXCR3 and CXCR4, in addition ... control (Dako, Ely, UK). The sec-tions were rinsed with PBS and incubated with biotinylatedsecondary antibody. The antibody binding was detectedusing reagents in the Vectastain ABC Elite kit...
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Báo cáo y học: "Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes" ppt
... earlybacterial infection in the joint. Somatic mutations in mitochondrial peptides displayed by MHCs may be recognizedas non-self, furthering the destructive immune infiltration of the RA joint. ... may also play a causative role in RA.Competing interests The author(s) declare that they have no competing interests.Authors' contributionsTD participated in the design of the study, ... thought that p53 is randomlymutated during chronic inflammation by oxygen radicals. Cer-tain mutations within p53 then confer a survival advantage to the synoviocytes, giving them 'transformed'...
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