Báo cáo y học: "Osteoimmunology in rheumatic diseases" pptx
Báo cáo y học: "Osteoimmunology in rheumatic diseases" pptx
... [23]. This link between
proinflammatory cytokines and osteoclast formation most
likely explains why cytokine-targeted therapy, particularly
blockade of TNF, is highly effective in retarding structural
damage ... lineage types such
as Kupffer cells in the liver or microglia in the brain. It is not
fully clear whether some monocytes entering an inflamed joint
are already committed to the...
Báo cáo y học: " Claudins in lung diseases" ppt
... cellular
integrity, and create hydrostatic pressure differentials
maintaining integrity of cystic compartments [31,32].
Additionally, claudin 1 may have a role in right-left
patterning of the embryonic ... causing infections are many some of which may
act by downregulating claudins or causing their
deranged distribution inducing changes in tight junc-
tional permeability allowing pathogen...
Báo cáo y học: "Vasculogenesis in rheumatoid arthritis" pptx
... origin as Lin
−
/7-aminoactinomycin D (7AAD)
−
/
CD34
+
/CD133
+
/VEGFR-2
+
cells and the number of these
cells was indeed higher in RA patients compared with
controls. In addition, the colony-forming ... late-outgrowth EPCs of solely
heman gioblastic origin may be involved in vascular
repair. As this EPC subset may be preferentially involved
in the active stage of the disease, i...
Báo cáo y học: "Cytokines in chronic rheumatic diseases: is everything lack of homeostatic balance" pps
... important
signaling pathways involved in the control of the IL-1/IL-1Ra
balance in human monocytes, in so far as inhibition of
phosphatidylinositide 3 kinase delta markedly decreases IL-1
while increasing ... the main problem is in fact the inhibition of
repair activity. Any type of chronic joint inflammation, whether
infectious, inflammatory, or autoimmune, will result in joint
des...
Báo cáo y học: "Modeling human arthritic diseases in nonhuman primates" ppsx
... (Panels 4,5) Increased urinary excretion
rates of hydroxylysylpyridinoline (HP) and lysylpyridinoline (LP) cross-
link products, expressed relative to creatinine (Cr), were observed
during the active ... of collagen cross-links as a biomarker
of joint erosion
Joint tissues contain different quantities of the major cross-
links hydroxylysylpyridinoline (HP) and lysylpyridinoline (LP),
which ar...
Báo cáo y học: " Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?" potx
... chemokine family, characteristically
heparin binding proteins which on structural level have
four highly conserved cysteine amino acid residues, with
the first two cysteines separated by one nonconserved
amino ... R, Lutze N, Schymeinsky J, Walzog B: Human neu-
trophils promote angiogenesis by a paracrine feedforward
mechanism involving endothelial interleukin-8. Am J Physiol
Heart Circ Physi...
Báo cáo y học: "Advances in immunomodulating therapy of HBV infection"
... respectively. Interestingly,
an increase in virological response over time after the discontinuation of thymosin could be observed (p=0.02) [40]. The doses of
thymosin α-1 in this meta-analysis are ... nucleoside
analogues, lamivudine and adefovir dipivoxil. The immunomodulators act by promoting cytotoxic T cell activity for lysis of
infected hepatocytes and by stimulating cytokine pr...
Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... intermediate intermediate No intermediate intermediate intermediate yes
DNA arrays na intermediate intermediate no high high low yes
Indirect
methods
Viral load na na na yes intermediate low low yes ... high intermediate low no
LiPA 5% low low-intermediate yes intermediate low low yes
Florescence nd intermediate intermediate no intermediate intermediate intermediate yes
MALDI-TOF <...
Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... its (already low) residual electron transfer
activity is not maintained by the neighbouring tyrosine,
while the W121F /Y1 22F mutant activity may be viewed as
a commitment of the tyrosine residue ... potential entry site: mutations in an exposed
tyrosine (Y2 26F; see Table 1) and in a histidine (H119N;
Table 2) show wild-type kinetics.
Biphasic steady-state kinetics
Non-linear kinetics ha...
Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... obtained by
analytical ultracentrifugation using the direct binding assay as des-
cribed in Experimental procedures. Inset: Linearized plot of the
binding data for apoE(263–286) (symbols) shown in ... possessing a
similar apparent binding affinity (K
d
) for the large lipid
particles, are notably distinct in their maximum binding
capacities (Table 2). In particular, the binding footpri...
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