... [1,4,5]. Receptor-activator of NFκB ligand (RANKL), a tumor necrosis factor super- family ligand expressed by stromal cells, osteoblasts, and activated T cells, binds to its cognate receptor-activator ... http://arthritis-research.com/content/5/1/R49 Research article Exposure to receptor-activator of NF κκ B ligand renders pre- osteoclasts resistant to IFN- γ...
Ngày tải lên: 09/08/2014, 01:21
... Community Respiratory Health Survey. Variations in the prevalence of respira- tory symptoms, self reported asthma attacks, and use of asthma medications in the European Community Respiratory Health ... diseases. 24 Approx- imately 80% of children with atopic eczema even- tually may develop rhinitis or asthma, suggesting a common systemic relation between respiratory allergy and atopic e...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Predictive network modeling of the highresolution dynamic plant transcriptome in response to nitrate" pps
... erred by ML), with the actual effect of over- expression of SPL9 on these genes measured by Q-PCR. The only systematic effect that we found is that genes predicted to be negatively regulated by SPL9 ... [2]. Predicted regulatory network influences The identification of regulatory networks is a major aim of systems biology. Relatively few studies have det er- mined regulatory n...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: "Epidemiology and Prevention of Hepatitis B Virus Infection"
... intramuscularly at 3, 2 and 1 month before delivery, in addition to newborns receiving HBIG intramuscularly. By this way, the rate of intrauterine transmission in this group fall to 5.7%, compared to 14.3% ... b b i i o o g g r r a a p p h h y y Jinlin Hou, MD, is Director and Professor of Hepatology Unit and Department of Infectious Diseases, Nanfang Hospital, Southern...
Ngày tải lên: 02/11/2012, 11:12
Tài liệu Báo cáo Y học: Dissecting the effect of trifluoroethanol on ribonuclease A Subtle structural changes detected by nonspecific proteases ppt
... trifluoroethanol. To gain insight into the changes detected by proteolysis (see below), we investigated RNase A in the absence and presence of 20% trifluoroethanol by NOESY and TOCSY NMR spectroscopy. However, ... generated by digestion of RNase A by subtilisin Carlsberg only. N -Terminal sequence determined Assigned RNase A Molecular mass determined by MALDI-MS (Da) Suggested...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues pptx
... transphosphorylation activity towards his- tone H1 (Fig. 3A, lane 3), recovery of the 32 P translocation into histone H1 being mediated by MAPK, possibly contaminating in the process of p25 rum1 prephosphoryla- tion, ... type cyclin and thereby regulate the cell cycle of fission yeast. Consistently, GST fusion p25 rum1 -WT effectively inhibited the phosphorylation of histone H1 media...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: "κ Increased AP-1 and NF-κB activation and recruitment with the β combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocyte" ppt
... arthritis joint and may contribute to the mode of action of cytokine inhibitors. Keywords: proinflammatory cytokines, rheumatoid arthritis, synoviocytes, transcription factors Open Access and ... Maloney W, Osdoby P: Receptor activator of NF-kappa B and osteoprote- gerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human os...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate" pot
... Matsushima Y, Kobayashi Y, Yamamoto T: Age estima- tion by measuring the racemization of aspartic acid from total amino acid content of several types of bone and rib cartilage: a preliminary account. ... degrada- tion. VI. Effect of the primary sequence on the pathways of degradation of aspartyl residues in model hexapeptides. Pharm Res 1994, 11:751-758. 6. Ohtani S, Ito R, Ar...
Ngày tải lên: 09/08/2014, 14:20
Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx
... deter- mined by Dokurno et al. [19]. They report a significant contribution of Arg4 to b inding by analyzing the surface of the residues covered by the protein. They also see an interaction of the C -terminal ... affinity of glycopeptides to the antibody [18]. Conventional pepscan analysis however, does not allow easy analysis of the contribution of the carbohydrate porti...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: A chimeric scorpion a-toxin displays de novo electrophysiological properties similar to those of a-like toxins docx
... properties of the models The existence onto the surface of scorpion a-neurotoxins of an electrostatic potential is suspected to contribute to the recognition of the receptor site [45]. By resolving ... arrangement of the toxin polypeptide chain together with the formation of an electrostatic potential are also predicted to participate to the capacity of these compounds...
Ngày tải lên: 08/03/2014, 23:20