Báo cáo y học: "The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis" ppsx
Báo cáo y học: "The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis" ppsx
... Research and Therapy Vol 5 No 1 Sumariwalla et al. Research article The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis Percy F Sumariwalla 1 , ... increased cellularity of the synovial lining of joints, before invasion by the synovium of the underlying cartilage and bone. This increased tissu...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... efficacy of the study medi- cation on their child's attention. The majority of caregiv- ers (93.1%) indicated a high level of satisfaction with the duration of effect of the study medication ... ER-MPH to the MTS dose specified by the dose-transition schedule. Thus, the safety data pre- sented herein should not be considered representative of the long-term saf...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"
... hepatobiliary system, genitourinary system, reproductive system, CNS and psychiatric conditions, and then to specify the name of that con- dition. If the participant failed to indicate the name of the ... pathways, the “voluntary path” and the “involuntary path” otherwise known as the “emotionally-driven path”. (5) The voluntary path- way begins from the premotor ope...
Ngày tải lên: 26/10/2012, 09:57
Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc
... responsible for the thermostability of Thermus thermophilus isopropylmalate dehydrogenase. Biochim. Biophys. Acta 1545, 174 –183. 5. Petsko, G.A. (2001) Structural basis of thermostability in hyperthermophilic ... than for xylose, and the relative effectiveness of the three metals was the same. Occupancy rate of the M2 site necessary for activity on glucose may be higher tha...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Baboon cytochrome P450 17a-hydroxylase/17,20-lyase (CYP17) Characterization of the adrenal microsomal and cloned enzymes docx
... formation of 16a-hydroxyprogesterone. Both expressed enzymes had no lyase activity towards PROG or 17-OHPROG. Understanding of the complexity of hydroxylase and lyase activity of CYP17 by way of primary ... 17a-hydroxylase (CYP17) cata- lyses not only the 17a-hydroxlation of pregnenolone and progesterone and the C17,20-side chain cleavage (lyase) of 17a-hydroxypregnenolone...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues pptx
... Cdc2 kinase inhibitor The p25 rum1 protein is known to inhibit the kinase activity of a complex of Cdc2 and B type cyclin and thereby regulate the cell cycle of fission yeast. Consistently, GST fusion p25 rum1 -WT ... phosphorylation. The yeasts have been the favored organisms for investiga- tion of the basic biology, genetics, and biochemistry of the cell cycle [1]....
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors potx
... protein synthesis, it will be important to consider their effects on protein synthesis when studying the effects of these stress conditions on cell physiology. Other agents that inhibit protein synthesis ... SDS/polyacrylamide gels containing 15% acryla- mide/0.4% methylene bis-acrylamide. For analysis of eEF2, gels contained 10% (w/v) acrylamide plus 0.1% methylene bis-acrylamide. For...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx
... necessarily indicative of either proper folding or of increased solubility of the protein of interest. We propose that the success of fusion protein systems should be ascertained only once the protein ... for the enhanced solubility phenomenon observed in Pfg27 A , we identified three key issues: (a) the role of the N-terminal extension; (b) the role of the D to N...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... because they s how structural similarity to the human brain endomorphins (e.g. YPWG-NH 2 ) [23]. The sequences of two tryptophyllins are as follows: tryptophyllin L1, FPWL-NH 2 ; tryptophyllin L2, ... omain of nNOS. FE BS Lett. 403,75. 51. For the sequences of various NOS enzymes together with the positions of the binding domains of the cofactors C a 2+ calmodu- lin. S W...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
... changes of these residues may dramatically affect the type a nd stability o f the turn [34,35]. To investigate the importance of t he type of the postulated turn for hCt b ioactivity, the i +1turn-residue L -Phe19 ... 19 of hCt and their chirality are strongly associated with receptor binding affinity (c) inversement of the chirality of residues 18 and 19 strongly redu...
Ngày tải lên: 31/03/2014, 21:21