Báo cáo y học: "The relationship between predicted peptide–MHC β class II affinity and T-cell activation in a HLA-DRβ1*0401 transgenic mouse model" pptx

... T-helper (cell). Arthritis Research and Therapy Vol 5 No 1 Hill et al. Research article The relationship between predicted peptide–MHC class II affinity and T-cell activation in a HLA-DR β 1*0401 transgenic ... whereas the remaining domains are mouse derived (IE d -α2 and IE d -β2 ). These mice were bred in a barrier facility (John P Robarts Barrier Faci...

Ngày tải lên: 09/08/2014, 01:21

... Portability and Accountability Act (HIPAA) compliant database contains information on patient demographics and hospitaliza- tions, outpatient service utilization, and outpatient phar- macy data from over ... disorder are substantial and include inpatient hospitalization, outpatient general and specialist visits, nursing home, intermediate, and domicil- iary care, medication, subst...

Ngày tải lên: 08/08/2014, 23:21

... Finally, the clinical relevance of these data regarding RA and malignancy is unclear. Should clinicians screen RA patients differently than typical patients? Competing interests The authors declare ... polyps as well as the risk of advanced adenomas at one and three years after randomization [5]. Use of immune modulating therapies in RA may also underlie the observed reduction in brea...

Ngày tải lên: 09/08/2014, 10:23

... cervical and the lum- bar spinal segments were analysed for spinal inflammation, similar to the available x-rays. To be even more precise in the relationship of inflammatory activity in MRI and ... only. For analysis of the relationship between spinal inflammation at BL and radiographic progression after 2 years, all individual VEs were examined by MRI for signs of inflammatio...

Ngày tải lên: 09/08/2014, 13:21

... anti-inflammatory therapy, rheumatoid arthritis (RA) patients continue to rate pain as a priority. The etiology of RA pain is likely multifactorial, including both inflammatory and non-inflammatory ... versa [57]. However, RA pain differs from fibromyalgia pain because RA pain frequently has an inflammatory component. Localized, inflammatory pain may cause sleep disturbance, which, in t...

Ngày tải lên: 09/08/2014, 14:22

... each day's main sleep period was inferred from urinary 6-sulphatoxymelatonin (aMT6s) excretion rates. All urine passed during a main sleep period was collected in a plastic bottle. At the ... during each day's main sleep period. The samples were subsequently assayed for the metabolite of melatonin in urine, 6- sulphatoxymelatonin (aMT6s), and the rate of excretion during m...

Ngày tải lên: 10/08/2014, 09:20

... the patellar and femoral articular cartilages, and can potentially aggravate osteophyte formation and also facilitate joint space narrowing. In the present study we used two indices of PF relationship: LPTA ... association between PLR and indices of radiographic PF OA in the medial PF compartment. SA showed a statistically significant association with medial joint space narr...

Ngày tải lên: 09/08/2014, 10:20

... murine TRAIL protein; AIA: Antigen induced arthritis; GAG = gly- cosaminoglycan; H&E = hematoxylin and eosin staining; IL = interleukin; LSF = lavage synovial fluid; MTT = 3-(4,5-dimethylthiazol-2-yl)-2,5-diphe- nyltetrazolium ... the saline control. Analysis of the glycosaminoglycan synthetic rate by cultured cartilage using radiolabeled sulfur and cartilage histology demonstrated th...

Ngày tải lên: 09/08/2014, 07:20

... independently and are nota- tionally quite different. TAG's deal with a set of elemen- tary trees composed by means of an operation called ad- joining. HG's maintain the essential character ... A -* f(al a, ) or A ~ ax where: A is a nonter- minal; a~ is either a nonterminal or a headed string; and f is either a concatenation or a head wrapping operation....

Ngày tải lên: 17/03/2014, 20:20

... dependent, and, depending on the enzyme, the pH stability and activity curves can in theory overlap totally, partially or not at all. When thinking of applying an enzyme at certain pH and temperature conditions, ... differentiated by using Origin 6.0 graphics and data analyses software. The culmination point of each curve was taken as the melting temperature. All points were measured...

Ngày tải lên: 31/03/2014, 07:20