... neurotransmitter/hor- monal imbalance and environmental factors. Many recent advances have been made in to understanding the complex interrelations of the neurocircuitry underpin- ning empathy and emotions. There ... Gamini Jayananda 1 Abstract Background: This review analyses and summarises the recent advances in understanding the neurobiology of violence and empathy,...
Ngày tải lên: 08/08/2014, 23:21
... microenvironmental conditions. Using RNA-interference, Yudoh and colleagues [1] further analyzed the role of HIF-1 in chondrocytic energy generation, matrix synthesis and cell survival. During hypoxic and normoxic ... In conclusion, the α-subunit of HIF-1 is stabilized and HIF-1 activity is significantly increased in chondrocytes by hypoxic, inflammatory and mechanical str...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "The Syndrome of Frontonasal Dysplasia, Callosal Agenesis, Basal Encephalocele, and Eye Anomalies – Phenotypic and Aetiologica"
... syndromes involving the frontonasal process that includes: isolated frontonasal dysplasia (MIM 136760 and 305645), acrofrontofacionasal dysostosis 1 (MIM 201180), acrofrontofacionasal dysostosis ... obtained by personal interview. Pregnancy history and delivery were unremarkable. There was no reference to toxic, infectious, or teratogenic agents during the pregnancy. Clinical, l...
Ngày tải lên: 03/11/2012, 10:05
Tài liệu Báo cáo Y học: The binding of lamin B receptor to chromatin is regulated by phosphorylation in the RS region ppt
... to b e predominant. Then, the binding is supported by the interaction of the NM region and a protein(s ) other t han HP1 on sperm chromatin. An assay system for the cell cycle-dependent binding of ... bound to chromatin. The b inding of GST-fusion proteins incorporating t he N-terminal and arginine-serine repeat-containing regions to chromatin was suppressed by mild tr...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc
... with 2-vinylpyridine and subjected to the recycling assay. The concentrations of total g lutathione and GSSG were calcu- lated from the absorbance change using authentic GSH and Ó FEBS 2002 Glutathione ... ystems. One is de novo synthesis from b uilding blocks, glutamate, cysteine, and glycine, via two ATP-con suming s teps involving c-g lut- amylcysteine synthetase ( cGCS) a...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase potx
... wild- type enzyme. Enzyme assays Wild-type DAOCS and all mutants were assayed for their ability to convert 2-oxoglutarate to succinate and carbon dioxide [17], and penicillin N and penicillin G to their corresponding ... [1,11,12], indicated that this mutation would be on the surface of the protein. All mutants and wild-type enzyme were purified to 85% purity (by SDS/...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: The amyloid precursor protein interacts with neutral lipids Liposomes and monolayer studies pdf
... in the orientation of the protein moiety during the insertion process into the monolayer film or into the bilayer containing the surfactant is also possible. The lower surface activity obtained ... considered the possibility that the pH-induced conformational transition may lead to changes in the protein quaternary structure. We have used gel filtration chromatography...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo sinh học: " The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon" doc
... of the pseudoknot in the 5' UTR and positions 10– 12, +15 to +17 and +19 with respect to the initiator AUG in the NPro coding region [30]. Interestingly, similar to the situation in CSFV the ... control vectors devoid of an IRES in the intercistronic region or carrying the inhibitory stem- loop in the 5'UTR of the dicistronic mRNA were inclu...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon" ppt
... Mutations and expression levelsFigure 6 Compensatory Mutations and expression levels. Top: In M7 the M6 mutations introduced in stem 1 are compensated, restoring stem 1 integrity and giving rise to ... cap-independent, internal initi- ation of translation. If the region in question is an IRES, translation of the second cistron may occur via internal entry of ribosomes...
Ngày tải lên: 20/06/2014, 01:20