... YG, Christen WG, Foster SC: Correlation of metal-loproteinase-2 and -9 with proinflammatory cytokines inter-leukin-1β, interleukin-12 and the interleukin-1 receptorantagonist in patients with ... inflammation,resulting in fibrosis. MMP-9 can trigger inflammationdirectly, by tissue destruction, or indirectly, by generation of an inflammatory signal or recruitment of inflammatory cells[32]. Infiltration ... demonstration of transform-ing growth factor-β isoforms in the skin of patients with sys-temic sclerosis. Clin Immunol Immunopathol 1993, 69:199-204.39. Ichiki Y, Smith EA, LeRoy EC, Trojanowska...