Báo cáo y học: "An analysis of correlations among four outcome scales employed in clinical trials of patients with major depressive disorder" pdf

... purposes) Annals of General Psychiatry Open Access Primary research An analysis of correlations among four outcome scales employed in clinical trials of patients with major depressive disorder Qin Jiang* ... [4-6]. The present analysis was undertaken in a large dataset of 22 double-blind, placebo-controlled, clinical studies of venlafaxine in pat...

Ngày tải lên: 08/08/2014, 23:21

... activity in the small intestine and the epididymis of mice. Arch Biochem Biophys 1980, 203:343-351. 33. Malina HZ, Martin XD: Indoleamine 2,3-dioxygenase: antioxidant enzyme in the human eye. Graefes ... Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest 2004, 114:280-290. 19. Munn DH, Sharma MD, Baban B, Harding HP...

Ngày tải lên: 09/08/2014, 10:22

... vari- ety of systems. This pyridine derivative is the oldest syn- thesised and reported specific inhibitor of Rho-kinase family enzymes. Y2 7632 inhibits ROCK activity by com- petitive binding with ... cones by increasing the net phos- phorylation of the myosin regulatory light chain. It also activates Rho kinase (ROCK) which directly phosphor- ylates the regulatory light chain of...

Ngày tải lên: 10/08/2014, 10:20

... 2011:29 http://www.journalofinequalitiesandapplications.com/content/2011/1/29 Page 5 of 14 RESEA R C H Open Access Some nonlinear delay integral inequalities on time scales arising in the theory of dynamics equations Qinghua ... 26D10. Keywords: delay integral inequality, time scales, dynamic equation, bound 1 Introduction In the 1980s, Hilger initiated the concept of time scale...

Ngày tải lên: 21/06/2014, 01:20

... vimentin is present in synovial membranes and is released in increased amounts in response to growth factors and proinflammatory cytokines, suggesting involvement in the pathophysiology of RA [24]. The ... largely subjec- tive [4]. Anti-filaggrin antibodies recognize citrulline residues formed by post-transcriptional modification of arginine by peptidy- larginine deiminase [5]. En...

Ngày tải lên: 09/08/2014, 01:22

... contri- buted greatly to our understanding of disc remodeling in degenerative IVD, notably the role of pro-inflammatory cytokines. They compare the expression of IL-1β and TNFα as well as their main functional ... with an increase in IL-1β compared to TNFα and a low level of cells positive for TNF receptor type I [1]. In degenerated human IVDs, although the protein production...

Ngày tải lên: 09/08/2014, 10:21

... vimentin is present in synovial membranes and is released in increased amounts in response to growth factors and proinflammatory cytokines, suggesting involvement in the pathophysiology of RA [24]. The ... largely subjec- tive [4]. Anti-filaggrin antibodies recognize citrulline residues formed by post-transcriptional modification of arginine by peptidy- larginine deiminase [5]. En...

Ngày tải lên: 09/08/2014, 13:22

... residues phenylalanine and tyrosine typical of the Ig-fold are bold in each domain. Fig. 5. Inhibition of in vivo myotoxicity of myotoxins I or II by DM64. Groups of four mice were injected intramuscularly ... DM64 binds to the myotoxins through a myotoxic/ cytolytic site distinct from the catalytic site, as already described for the inhibition of myotoxicity by heparin [44]....

Ngày tải lên: 21/02/2014, 01:21

... Protein conxentration was determined using the Bio-Rad protein assay reagent (Bio-Rad Laboratories Inc., CA, USA). Data analysis Steady state kinetic analyses for P450foxy were examined with varying ... x-3 hydroxy fatty acids, respectively. 2080 T. Kitazume et al. (Eur. J. Biochem. 269) Ó FEBS 2002 Kinetic analysis of hydroxylation of saturated fatty acids by recombinant P450foxy p...

Ngày tải lên: 08/03/2014, 22:20

... histological analysis of injected joints revealed a high incidence of disease transfer (Table 1), characterized by variable degrees of synovitis, soft-tissue inflammation, synovial hyperplasia, ... the presence of the transgene could be detected in only the injected knee. Careful analysis of the fibroblast-containing organs did not show any evidence of tissue pathology; this...

Ngày tải lên: 09/08/2014, 01:21