Báo cáo y học: "Alcohol significantly lowers the seizure threshold in mice when co-administered with bupropion hydrochloride" ppsx

... purposes)Annals of General PsychiatryOpen AccessPrimary researchAlcohol significantly lowers the seizure threshold in mice when co-administered with bupropion hydrochloridePeter H Silverstone*1, ... of seizures since bupropion- induced seizures aredose dependent. Similarly, a previous study [8] investigat-ing the interactive effect of combined treatment with alco-hol and bupropion in adult ... 5 min prior to bupropion dosing. The presence or absence of seizures, the number ofseizures, the onset, duration and the intensity of seizures were all recorded for 5 h following the administration...

Báo cáo y học: "Transporter Molecules influence the Gene Expression in HeLa Cells"

... employed the Fmoc (9-fluorenyl-methyloxycarbonyl) methodology [37, 38] in a fully automated multiple synthesizer (Syro II from Multi Syntech Germany). As coupling agent 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylu-roniumhexafluoro-phosphate ... processing and analyzing with Illumina’s BeadStudio Data Analysis Software and are described in the following part according the defini-tions of the Illumina’s (ILL) data as well as of the Il-lumina’s ... capacity [41]. Iron ion proteins (GO:0005506) are con-sidered as key players in vital processes involving energy homeostasis and metabolism in many organ-isms [42]. The fact that the search in the...

Báo cáo Y học: Biophysical characterization of the interaction of high-density lipoprotein (HDL) with endotoxins doc

... a cylindrical shape are not able toinduce this stress. They are therefore agonistically inactive,but may block the action of active endotoxins byoccupying the binding-sites [33]. According ... The succeedingcooling scan reveals only a very small hysteresis for the re-crystallization of the acyl chains from the liquid crystal-line to the gel phase. The maximum of the heat capacitycurve ... backboneand the 4¢-phosphate of lipid A. The binding-places within the HDL moiety at present cannot be given. A furtherpossibility of LPS binding to HDL, an incorporation of the LPS bilayer into the...

Báo cáo toán học: "A note on the component structure in random intersection graphs with tunable clustering" pptx

... speciﬁed shortly. The construction used in the proof issimilar but more involved than the one of the ﬁrst part of the proof.For the remainder of the proof we will implicitly condition on the event ... increases, we expect an exponential decay of probabilities away from the mean of the sum. Since C is not further speciﬁed, this bound is only useful as k tends to in nity,which it may or may ... [7], the vertexdegree distribution of the random intersection graph is highly dependent on the value ofα, but as shown by Deijfen and Kets [3], the clustering is tunable only when α ≡ 1. In arecent...

Báo cáo y học: "Comparative responses to nasal allergen challenge in allergic rhinitic subjects with or without asthma" potx

... topenetrate into the lower airways, inducing inflammation,and potentially triggering asthma symptoms. The other objecti ve was to compare the i nflammatoryresponse of allergic rhinitic subjects with ... quantity of s olut ion sprayedinto the nose. With the pump spray delivery method, noallergen should penetrate in the lower airways if the subjects previously inhaled to total lung capacity andheld ... extract chosen,either cat hair or D. pteronyssinus, beginning with the concentration pre-determined by skin titration. B eforespraying, subjects were asked to inhale through theirmouth to total...

Báo cáo y học: "Alcohol use and abuse in training conscripts of the Hellenic navy" pps

... frequency of alcohol that is in fact bingedrinking. Since the questionnaires used provide indirectinformation about binge drinking habit in conscriptbehaviour. The high level of problematic drinking ... to conditions within the Navy as the testing of the conscripts was carried out training period i.e. second andthird week. During that time the conscripts stay continu-ously in the enlistment ... positively in problem-atic alcohol drinking. The above high percentages are in accordance with the results of other studies among youngpeople in Greece [38] and the increasing frequency ofbinge...

Báo cáo y học: "Users' guides to the medical literature: how to use an article about mortality in a humanitarian emergency"

... keep in mind when reading amortality survey to determine the validity of the study and the applicability of the findings to theirsettings.Public health scenarioYou are a physician working ... mortality isoccurring, by comparing the observed mortality rate with the best available estimate of the baseline mortality rate in the pre-war period, either by subtraction or by modellinga relative ... opening public health scenario, howwell did the study assessing nation-wide mortality in the DRC achieve the goal of representing the underlying pop-ulation? The investigators tell us that they...

Báo cáo y học: "Anticancer Activity of the PR Domain of Tumor Suppressor RIZ1"

... Huang S, Shao G, Liu L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. ... domain is due to its methyltransferase activity or the interaction with the PRB motif. Further studies with a methyl-transferase inhibitor specific for the PR domain may help to understand the ... pro-tein-binding zinc finger protein 1 (RIZ1). Int J Mol Sci 2008; 9: 943-50. 21. Chen L, Ling B, Alcorn J, Yang J. Analysis of the expression of human N-myristoyltransferase 1 (hNMT-1) in cancers....

Báo cáo y học: " Experimental ablation of the pancreas with high intensity focused ultrasound (HIFU) in a porcine model"

... Biochemistry parameters In the present study, the amylase levels in the serum and urine were increased in the first 3 days and the first 5 days after HIFU ablation, respectively. But no significant ... Thus, safety remains the main con -cern of any medical intervention of the pancreatic diseases. A previous preclinical in vivo study in swine demonstrated the feasibility and safety of H I ... efficacy and safety. To evaluate the rela-tionship between HIFU energy and pancreas histol-ogy, a preclinical in vivo study was conducted in swine demons t rat ing the feasibility and safety of...

Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"

... might in turn result in the uncertainty of the strategy for its treatment. While further delineati n g the clinicopathological and radiological features, and summarizing the surgical therapy strategy ... 4-20). Nine patients had their tumors within the head, 2 in the body and 7 in the tail of the pancreas. Notably one patient was demonstrated to have liver metastasis. The predominant presenting ... the experience with the management of disseminated disease is very limited in the literature6, therefore, attention to the therapy strategy of this neoplasm in the future may allow a more...

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