... Matsuura K, Sakamoto N, Nakagawa M, Korenaga M, Hino K, Hige S, Ito Y, Mita E, Tanaka E, Mochida S, Murawaki Y, Honda M, Sakai A, Hiasa Y, Nishiguchi S, Koike A, Sakaida I, Imamura M, Ito K, Yano ... IL28B. Variant calling and association testing CRISP detected 1221 SNVs and 118 indels (1339 var- iants in total). Validation with original GWAS SNP data and HapMap data CRISP called all 15 o...
Ngày tải lên: 11/08/2014, 12:21
... Ma J & Jiang H (2005) Conformational transition of the amyloid b-peptide. Proc Natl Acad Sci USA 102, 5403–5407. 25 Lemkul JA & Bevan DR (2008) A comparative molecu- lar dynamics analysis ... Area per lipid headgroup as a function of time for control DPPC simulations. Fig. 5. Area per lipid headgroup as a function of distance from the protein; simulations A1 and A2 are...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area ppt
... the antisense primer 5¢-AAG AAT TCT AGA TTA ATG GTG ATG ATG GTG ATG ATG GTG TGG GGT CAG CGG TGC AGC AGG GGG GGT-3¢ (XbaI sites underlined; His-tag in italic) and pVL1393–HSL [18] as template was ... by bis-ANS was decreased upon phosphorylation. A possible explana- tion for this apparent discrepancy could be that PKA phosphorylation induces a conformational change that increases the acc...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: "Integration of Speech to Computer-Assisted Translation Using Finite-State Automata" pdf
... (Papineni et al., 1997; Papineni et al., 1998) for a natural language understanding task, by (Beyerlein, 1998) for an ASR task, and by (Och and Ney, 2002) for an MT task. This approach is a generalization ... target part of these phrases we build a transducer similar to the lexicon-based transducer. But instead of a target word on each arc, we have the target part of a p...
Ngày tải lên: 20/02/2014, 12:20
Báo cáo khoa học: Transport of L-arginine and nitric oxide formation in human platelets pdf
... intolerance (LPI). Hum. Mol. Gen. 9, 431–438. 42. Kamada, Y., Nagaretani, H., Tamura, S., Ohama, T., Maruyama, T.,Hiraoka,H.,Yamashita,S.,Yamada ,A. ,Kiso,S.,Inui,Y., Ito, N., Kayanoki, Y., Kawata, ... the addition of cold 2 M perchloric acid. Extracts were neutral- ized and analyzed for the cGMP content by RIA kit. Data analysis Data are the mean ± SD of at least four independent deter...
Ngày tải lên: 08/03/2014, 02:20
Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc
... performed transfection assays with increasing amounts of DNA fragments encoding cyt b 5 and monitored the formation of androstadienol and DHEA. As shown in Fig. 5 the stimulation of DHEA and androstadienol production ... used as standards, showed elution peaks at 4.70, 2.30 and 2.50 min, respectively (Fig. 2). In both porcine and human assays using preg as a substrate, an additional p...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: "EVALUATION OF NATURAL LANGUAGE INTERFACES TO DATABASE SYSTEMS: A PANEL DISCUSSION " ppt
... EVALUATION OF NATURAL LANGUAGE INTERFACES TO DATABASE SYSTEMS: A PANEL DISCUSSION Norman K. Sondheimer, Chair Sperry Univac Blue Bell, PA For a natural language access to database system ... intermedlary[l]? What are the independent variables that must be allowed for? What tools are available to determine user bias and experience beforehand, and user satisfaction afterward?...
Ngày tải lên: 08/03/2014, 18:20
Báo cáo khoa học: Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting pdf
... Berdiaki A, Kletsas D, Zafiropoulos A, Theocharis AD, Tzanakakis GN & Karamanos NK (2008) Estradiol–estrogen receptor: a key interplay of MMPs as potential targets in malignancy C. Gialeli et al. 26 ... both apoptotic and anti-apoptotic actions. MMPs and ADAMs, especially MMP-7 and ADAM10, confer anti-apoptotic signals to cancer cells by cleaving Fas ligand, a transmem- brane stim...
Ngày tải lên: 15/03/2014, 00:20
Báo cáo khoa học: Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand pptx
... Casado S, Alonso M, Herrado ´ n B, Tarazona J & Navas J (2006) Activation of the aryl hydrocarbon receptor by carbaryl: computacional evidence of the ability of carba- ryl to assume a planar ... system, carbaryl acted as an antagonist because simultaneous addition of 1 lm of a typical AhR ligand, b-naphthoflavone (BNF), and increasing concentrations of carbaryl resul- ted i...
Ngày tải lên: 16/03/2014, 10:20
Báo cáo khoa học: Binding of non-natural 3¢-nucleotides to ribonuclease A ppt
... with water. (The pH of the water wash was % 13) Glacial acetic acid (0.5 mL) was added, the layers were separated, and the organic layer was washed again with water. The layers were separated, and ... 3¢-nucleotides with a non-natural furanose ring can have a greater affinity for a ribonuclease than do 3¢-nucleotides with a ribose or deoxyribose ring. The values of K i for inhi...
Ngày tải lên: 16/03/2014, 18:20