... markers. The latter have the particular advantages of being present from the onset of the disease and of remaining unchanged by therapy. To date, the only genetic susceptibility factor identified for ... value and are not routinely used in the diagno- sis of RA because they are not part of the ACR criteria for the diagnosis of RA. Taking into account a single g...
Ngày tải lên: 09/08/2014, 06:23
... excision of the lesion with sparing of the umbili- cus is the preferred treatment of pelvic endometriosis [7]. In severe cases or in the presence of pelvic endometriosis, hormonal therapy in the form ... publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-chief of this journal. Co...
Ngày tải lên: 11/08/2014, 14:21
Báo cáo Y học: Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101) A high-pressure stopped-flow study pdf
... increasingly accumulated indica- ting that the dynamics of the protein structure and in particular the accessibility of the active site for water molecules are very important [3]. In the oxidized form of P450 ... route of the reaction cycle from the substrate to the product there are side reactions which lead to the production of cytotoxic oxygen species such as...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo y học: "Pre- and post-operative gait analysis for evaluation of neck pain in chronic whiplash" pptx
... the Plug-In-Gait full body model, and the maximum angle for each of three trials was identified for each direction of movement. The average of the three trials was used as outcome meas- ure for ... of upper body dysfunction, The present investiga- tion was designed for that purpose and, secondly, to assess the usefulness of computerized 3D gait analysis to object...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx
... further investigation. In addi- tion, the question of how PTP-α acts as an Scr-PTK activa- tor should now be addressed. Nevertheless, these data highlight the role played by PTP-α as a key upstream ... regulation of integrin sig- nalling in RA-SFs and the relevance of Src-PTK/FAK for- mation for synovial cell activation. This is in striking contrast to the multitude of dat...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo khoa học: "Single fraction radiosurgery using Rapid Arc for treatment of intracranial targets" potx
... an advantage for patients because of less scattered radiation and for the daily routine of the department because of better time utilisation of the accelerators. Interestingly, size of target GTV ... system. The camera system was verified before patient setup. Due to the ver- ification process the camera system saves the position of the linac based isocenter in...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo y học: " Review of the use of Topiramate for treatment of psychiatric disorders" pptx
... purposes) Annals of General Psychiatry Open Access Review Review of the use of Topiramate for treatment of psychiatric disorders Danilo Arnone* Address: Department of Psychiatry, Springfield University Hospital, ... that in the light of cur- rent evidence, there is limited scope for the use of topiramate in acute mania. The only randomised single blind...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: " Review Cells of the synovium in rheumatoid arthritis" ppsx
... in the K/B×N mouse model of arthritis discussed above through induction of FcγRIIB [38]. This property of IVIG has been linked to sialylation of the Fc portion of IgG. The proportion of sialylated ... may account for the very mixed results obtained when patients with RA were treated with IVIG [39]. Involvement of the complement system in the development of mouse...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: " Review Cells of the synovium in rheumatoid arthritis" pot
... Page 2 of 12 (page number not for citation purposes) Arthritis Research & Therapy Vol 9 No 4 Lutzky et al. the clinic some of the hypotheses generated over the past 20 years of DC research ... and RA synovial inflammation Gene transcriptional activity of the NF-κB family is charac- teristic of the RA inflammatory lesion. There are two major pathways of NF-κB: the...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Review Cells of the synovium in rheumatoid arthritis" pot
... components has offered the possibility of identifying patients at risk for rapid joint damage and also the possibility of early monitoring of the efficacy of disease-modifying anti-rheumatic therapies ... that the chondrocytes may not only participate in the destruction of the cartilage matrix by responding to the proinflammatory cytokines released from the synoviu...
Ngày tải lên: 09/08/2014, 10:21