Báo cáo y học: "Aspirin-Exacerbated Asthma" pps

... (eg, RANTES) known to be produced by lymphocytes, are also synthesized, stored and released by eosinophils. These cells may also be involved in airway re- modelling through tenascin production; ... eosinophils may not play a signicant role in airway hyper- responsiveness. There was also doubt whether the presence of eosinophils in sputum or airway uids truly reected those in the air...

Ngày tải lên: 08/08/2014, 21:20

Ngày tải lên: 08/08/2014, 20:23

... early intro- duction of long-term low-dose ICS therapy in young children with mild asthma may ultimately reduce the peak bone mass that they attain at maturity. A baseline DXA measurement may be appropriate ... per day. 9 However, regardless of the daily dose, DXA should be sought routinely in elderly asthmatic patients receiving ICS or prednisone treatment because a majority may exhibit a cl...

Ngày tải lên: 08/08/2014, 20:23

... sur- prising by many. They provide convincing evi- dence that airway eosinophilia and airway hyper- responsiveness may not be as closely linked as had been previously assumed. This is one way in which ... activity. Airway eosinophilia, along with the LAR and airway hyperresponsiveness, can be induced by exposure to allergen. 7,8 Eosinophilia, LARs, and airway hyperresponsiveness are all inhib...

Ngày tải lên: 08/08/2014, 20:23

... with asthma, immunotherapy improved methacholine hyper- reactivity and quality of life and reduced seasonal asthma symptoms. 51 Reducing the allergen sensi- tivity not only leads to relief of rhinitis ... syndrome of airway inflammation. Ann Allergy Asthma Immunol 2002;88:8–15. 6. Leynaert B, Neukirch F, Demoly P, Bousquet J. Epidemiologic evidence for asthma and rhinitis comorbidity. J Aller...

Ngày tải lên: 08/08/2014, 20:23

... manipulation in preg- nancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial. Lancet 2001;358:188–93. 27. Celedon JC, Litonjua AA, Ryan L, et al. Exposure to ... Canadian Family Physi- cian’s Asthma Group, Richmond Hill, Ontario; Sandeep Kapur, MD, Dalhousie University, Halifax, Nova Scotia; Cheryle Kelm, BPT, MSc, University of Cal- gary, Calgary...

Ngày tải lên: 08/08/2014, 21:20

... MDD. They are produced by almost all cell types and participate in the inflammatory cascade that occurs in airways. 142 PGs D 2 ,E 2 , and F 2 have a variety of effects on airway physiology, including ... a shared pathophysiologic vulnerability. Alternatively, there may be aspects of dysregulation in key biologic systems, such as the neuroendocrine stress response or cytokine system, that pre...

Ngày tải lên: 08/08/2014, 21:20

... Suh YJ, Park HS, et al. Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthma. J Pathol 2006;209:392–9. 54. El Miedany Y, Youssef ... AEA. The pathogenesis of AEA involves the cyclooxygenase and lipooxygenase pathway. Aspirin affects both of these pathways by inhibiting the enzyme cycooxygenase-1 (COX-1). Inhibition of COX-...

Ngày tải lên: 08/08/2014, 21:20

... depression: a biopsychosocial pespective. Biol Psychiatry 2003, 54:399-409. 15. Kunik ME, Roundy K, Veazey C, Souchek J, Richardson P, Wray NP, Stanley MA: Surprisingly high prevalence of anxiety and depression ... everyday needs. This inadequacy may lead to heightened anxiety and depression, which in turn may worsen the everyday inad- equacy. It has been reported that this is (probably) a fa...

Ngày tải lên: 08/08/2014, 23:20

... been reported [8]. We also frequently observe protein hyperacetylation in RA stromal FLS (35 ± 7%), but rarely in synovial B lymphocytes (22 ± 3%) and T lymphocytes (12 ± 2%). A pressing question that ... 107:523-531. 86. Yang QC, Zeng BF, Shi ZM, Dong Y, Jiang ZM, Huang J, Lv YM, Yang CX, Liu YW: Inhibition of hypoxia-induced angiogenesis by trichostatin A via suppression of HIF-1a activity...

Ngày tải lên: 09/08/2014, 11:20