... extensively studied in adults, nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity in children, especially in youngchildren, remains poorly defined. Pediatricians, prescribing antipyretics ... NSAID hypersensitivity in preschool children.Key words: acetaminophen, acetylsalicylic acid (ASA), children, hypersensitivity, ibuprofen, NSAID, preschool Acetylsalicylic acid (ASA) and other nonsteroidal ... resulting in increased production and release ofcysteinyl leukotrienes.Although extensively studied in adults, NSAID hyper-sensitivity in children, especially in young children,remains a poorly...