... mTOR, suggests the pos-sibility that the insulin–AKT–FoxO3 signaling cascademay play more prominent roles in the insulin signaling-dependent regulation of autophagy in C. elegans.Indeed, Jia ... further examination of the vari-ous regulatory pathways is needed, including the com-plex network of multiple autophagy inducing – and inhibiting – signals, and, more importantly, the systemic ... Signalling and auto-phagy regulation in health, aging and disease. MolAspects Med 27, 411–425.52 van der Horst A & Burgering BM (2007) Stressing the role of FoxO proteins in lifespan and...