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... MINIREVIEW Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy Isamu Okamoto Department of Medical Oncology, Kinki University School of Medicine, ... sensitivity to therapy with mAb to epidermal growth factor receptor in colorectal cancer Cetuximab is a chimeric mouse–human mAb that tar- gets the extracell...
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... GIF, neuronal growth-inhibitory factor; hGIF, human neuronal growth-inhibitory factor; MT, metallothionein; NO, nitric oxide; pDB, protein data bank; rlMT2, rat liver MT2; sGIF, sheep neuronal growth-inhibitory ... The Authors Journal compilation ê 2010 FEBS 2917 MINIREVIEW Neuronal growth-inhibitory factor (metallothionein-3): structure–function relationships Zhi...
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... discovery of a brain- specific MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs in the brain, and particularly within the injured or diseased brain. In the ... isoform has led to intense interest in the roles of the entire MT family in the brain, with particular focus on the role of these proteins in the...
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