Báo cáo y học: "A 12 Week, Open Label, Phase I/IIa Study Using Apatone® for the Treatment of Prostate Cancer Patients Who Have Failed Standard Therapy" pps
Báo cáo y học: "A 12 Week, Open Label, Phase I/IIa Study Using Apatone® for the Treatment of Prostate Cancer Patients Who Have Failed Standard Therapy" pps
... capsule every two hours for six doses followed by two capsules at bedtime for a total of ten capsules per day. Following the 12 week study, two of the three “non-responders” in the study who had ... options for androgen independent prostate cancer (AIPC) patients. Therefore, there is a substantial need for new therapeutic options. Because of their relative...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo y học: " Bronchoalveoloar lavage fluid cytokines and chemokines as markers and predictors for the outcome of interstitial lung disease in systemic sclerosis patients" pps
... diseases), with the written informed con- sent of patients for diagnostic or clinical purposes. Patients with present pulmonary infections were excluded from the study. The study was approved by the local ... immunosuppressive therapies. Another limi- tation of the study is the low number of patients and the heter- ogeneity of the control group. In conclus...
Ngày tải lên: 09/08/2014, 14:22
báo cáo hóa học:" Two levels above and one level below pedicle screw fixation for the treatment of unstable thoracolumbar fracture with partial or intact neurology" pot
... instability criteria of kyphotic deformity of more than 20° and/or vertebral body height loss of more than 50 compared to vertebra below. The senior author (KJC) performed all surgeries. At surgery, the ... and early mobilization for burst fractures of the thoracolumbar junction. Eur Spine J 1996, 5: 112- 120. 21. Cho DY, Lee WY, Sheu PC: Treatment of thoracolumbar burst f...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx
... randomized, double-blind, placebo-controlled, study of the efficacy and safety of aripiprazole 10, 15 or 20 mg/day for the treatment of patients with acute exacerbations of schizophrenia. J Psychiatr Res 2007, 41(11):895-905. 15. ... the prestudy medication. Safety and tolerability Of the 245 subjects who were included in the safety sample, 163 (66.5%) experience...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Successful immunotherapy with matrix metalloproteinasederived peptides in adjuvant arthritis depends on the timing of peptide administration" pdf
... depicted as the percentage of the body weight at the time of AA induction. Data shown are the percentage of the body weight of two experiments (n = 10 rats per group) ± standard error of the mean. ... observed. Discussion In the present study, we explored the possibility of using recently identified MMP T-cell epitopes for immunotherapy in AA. First, we moni...
Ngày tải lên: 09/08/2014, 03:24
Báo cáo y học: "Dipeptidyl peptidase IV activity and/or structure homologs: Contributing factors in the pathogenesis of rheumatoid arthritis" doc
... of Cancer Cell Biology of the 1 st Faculty of Medicine, Charles University, Prague and the Institute of Physiology, Academy of Sciences, Prague, Czech Republic 2 Department of Medical Oncology, ... difference in DPPIV activity in the sera of RA patients compared to the normal controls, but the study groups in this report were not delineated by disease severity, t...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7" pps
... develop OA sponta- neously; therefore, they can be used as a model of primary OA. In STR/ort mice, OA progresses relatively slowly. Therefore, we examined the final result of TGF-β and Smad7 overexpres- sion ... histological analysis of synovial fibrosis and PG content of the cartilage. Histology Knee joints of mice were dissected and fixed in phosphate- buffered formalin for...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases" ppt
... membranes of RA patients, because the sensitivity of in situ hybridization is lim- ited [50]. In the previous study, the synovial lining cells of RA patients were stained by the anti-IL-32 antibody [16]. ... in the synovial tissues of RA patients by in situ hybridization (Figure 2a). We detected abundant IL-32 expres- sion in the synovial-infiltrated lymphocytes of...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab" ppt
... [16]. Although these techniques are valuable for the understanding of the contribution of local antibody synthesis to the pathogenesis of RA, their applicability in interventional biopsy-based clinical ... study. The other authors declare that they have no competing interests. Authors' contributions SR participated in the design of the study, developed and per-...
Ngày tải lên: 09/08/2014, 13:21
Báo cáo y học: "Capturing real-life patient care in psoriatic arthritis and its risks: the challenge of analysing registry data" docx
... unacceptable toxicity; however, the vast majority of patients will have some combination of the two, which will hamper a clear adjudication of the reason for withdrawal. In summary, the study by Saad and ... the methodology of looking at all treatment terminations and then at only those terminations for the reason of ineffectiveness and terminated for the...
Ngày tải lên: 09/08/2014, 14:20