... 3 A˚ of N5 of the isoalloxazine ring of the flavin. Agmatine, however,binds poorly to MAO-A, giving only 50% inhibition of the oxidation of 0.3 mm kynuramine at 1 mm.Docking of imidazolines ... forms of monoamine oxidase, monoamine oxidase A and mono-amine oxidase B, have been associated with imidazoline-binding sites (type2). Imidazoline ligands saturate the imidazoline-binding sites ... their active site binding and the resultinginhibition. The use of purified enzyme simplifies thesystem for kinetics and also allows observation of thespectrum of the flavin cofactor in MAO-A. The...