NEUROVASCULAR MEDICINE - Pursuing Cellular Longevity for Healthy Aging Part 2 ppt

Ngày tải lên: 23/12/2013, 11:15

... powerful TOEFL vocabulary. ANSWERS TO TOEFL VOCABULARY TESTS Practice Test 1 Practice Test 2 1.B 11.A 21 .A 1.D 11.A 21 .B 2. C 12. B 22 . D 2. B 12. B 22 . A 3.D 13.C 23 .B 3.A 13.D 23 .C 4. ... motors. The entry features the word intricate. Directly under the word, you will find other forms of the same word. These words have the same general meaning; th...

Ngày tải lên: 23/12/2013, 13:16

... University Press. Library of Congress Cataloging-in-Publication Data Neurovascular medicine: pursuing cellular longevity for healthy aging / [edited by] Kenneth Maiese. p. ; cm. Includes bibliographical ... â 2009 by Oxford University Press, Inc. Published by Oxford University Press, Inc. 198 Madison Avenue, New York, New York 10016 www.oup.com Oxford is a registered trademark...

Ngày tải lên: 11/06/2014, 10:12

Ngày tải lên: 07/07/2014, 14:20

... PS DAG Choline GTP IP 3 RhoA Ca 2+ CaM MLCK active inactive MLCK MLC-P MLC MLC Phosphatase Rho-kinase CPI -1 7 CPI -1 7 -P MYOSINACTIN CONTRACTION MAPK GDP PKC PKC SR MEK CaP-P Actin-CaP Actin-CaD CaD-P Actin Raf lipase ADP ATP P i Figure 2 .1 Cellular mechanisms ... Mercadante et al. 2007. 51 90 10 5 11 9 12 8 14 4 17 2 17 9 19 2 COOH Laminin NCAM Laminin receptor 37/67 kDa p75...

Ngày tải lên: 08/08/2014, 13:20

... ˚C 2. 5 2. 0 1.5 1.0 0.5 –0.5 –40 Hippo Muscle Hippo-muscle NAcc-muscle NAcc –40 04080 04080 –0.1 0.0 0.1 0 .2 0.3 0.4 0.5 0.6 0.7 –0 .2 43 42 41 40 39 38 37 36 35 –60 0 60 120 Time, min 180 24 0 ... concentration, mg%; (D) numbers of albumin- and GFAP-positive cells). All values (4 for control, 8 for METH 23 °C, and 8 for METH— 29 °C, a total n = 20 ) were accepted for this...

Ngày tải lên: 08/08/2014, 13:20

... (γ-interferon, IL-2, IL-12, IL-18, TNF, etc.). On the contrary, enhanced corti- sol level inhibits the thymus gland and increases the plasma values of TH-2 cytokines (IL-4, IL-6, IL-10, β-interferon, ... with TH-2 immunolog- ical pro le, which is caused by low CD4/CD8 ratio, low NK-cell cytotoxicity against K-562 target cells, and low plasma levels of TH-1 cytokines (IL-2, IL-12, IL-18,...

Ngày tải lên: 08/08/2014, 13:20

... insulin and of IGF-1, whose effective activity is increased in the context of IR to boost activity of the transcription factor hypoxia-in- ducible factor- 1- (HIF- 1- ), may be at least partially responsible ... Alford F, Best JD. 1996. Low density lipoprotein particle size in hypopi- tuitary adults receiving conventional growth hor- mone replacement therapy. J Clin Endocrinol Metab....

Ngày tải lên: 08/08/2014, 13:20

... glutamate receptor agonists at 100 àM for 12 consecutive days, followed by deter- mination of mitochondrial activity with 3-( 4, 5- dimethyl-2-thiazolyl )-2 , 5- diphenyl-2H-tetrazolium bromide (MTT) reduction ... Neurologist. 13(3):1 05 117. Raber J, Huang Y, Ashford JW. 2004. ApoE genotype accounts for the vast majority of AD risk and AD pathol- ogy. Neurobiol Aging. 25( 5):...

Ngày tải lên: 08/08/2014, 13:20

... provide co-stimulatory sig- nals for T-cell activation and that are represented VCAM-1 VLA-4 B7 CD40 MHC-II CD3 TCR CD4 LFA-1ICAM-1 LFA-3 Ag CD40L CD28 CD2 VCAM-1 VLA-4 B7 CD40 MHC-I CD3 APC APC A B CD8 + CD4 + TCR CD8 LFA-1ICAM-1 LFA-3 Ag CD40L CD28 CD2 Figure ... Wang et al. 2007 Cytokines IL-1, TNF-α, IL -6 , IL-10, TGF-β Chemokines IL-8, IP-10, MCP-1, MIP-1α Transcriptional regulators...

Ngày tải lên: 08/08/2014, 13:20

... CM COS -7 cells COS -7 CM HFF cells HFF CM K-562 cells K-562 CM U- 373 cells U- 373 CM SK-N-BE cells SK-N-BE CM SH-SY5Y cells SH-SY5Y CM CHP-100 cells CHP-100 CM Chapter 16: Proteases in 𝛃 -Amyloid ... measured in a γ-counter. Fraction No A: Non-neuronal cells B: Neuronal cells 5 0 7 14 0 7 14 0 7 14 0 7 PI PII PI PII A A CPMì10 3 CPMì10 3 CPMì10 3 CPMì10 3 14 0 7 14 0 7 14 0...

Ngày tải lên: 08/08/2014, 13:20

... interleukins, IL-1, IL-6, and IL-10, transforming growth factor-α (TGF-α), and TNF-α. Among those cytokines, IL-1 and TNF-α appear to exacerbate cerebral injury; how- ever, IL-6, IL-10, and TGF-α may ... inducible CD 18/ 11α(LFA-1, αLβ2) VCAM-1 Endothelium, constitutive and inducible CD 18/ 11β(Mac-1, αMβ2) VLA-4 (α4β1) Integrins CD 18/ 11α(LFA-1, αLβ2) Neutrophils/macrophages, constitut...

Ngày tải lên: 08/08/2014, 13:20

... p38 MAPK activa- tion/↑ c-Fos, c-Jun and JunB expression, ↑AP-1 activity Mitogenesis associated with atherosclerosis, aging, or cancer Rao et al. 199 9 ↑ROS-RNS/↑AP-1 activity/↑MMP-2/cardiac remodeling Response ... Benson JM, Henderson RF. 198 5. Effects of the long-term depletion of reduced glu- tathione in mice administered L-buthionine-S, R-sulfoximine. Fundam Appl Toxicol. 5(5) :91...

Ngày tải lên: 08/08/2014, 13:21

... signaling pathways in, 551 Amadorins, 527, 529t γ-Amino butyric acid (GABA), 104 , 156, 270 Aminoguanidine, 526, 530 α-Amino-3-hydroxy-5-methyl- 4-isoxazole propionate (AMPA) receptors, 155, 158, ... (DSA), 512 Dihydroergotamine, 122, 131, 132, 133f 3,5-dihydroxyphenylglycine (DHPG), 273 3-( 4,5-dimethyl-2-thiazolyl )-2 ,5-diphenyl - 2H-tetrazolium bromide (MTT), 273 Dipeptidyl...

Ngày tải lên: 08/08/2014, 13:21