Báo cáo khoa học: "Low dietary inorganic phosphate affects the lung growth of developing mice" pps

... Factors affecting the specificity of Fpg and OGG1 FEBS Journal 275 (2008) 3747–3760 ª 2008 The Authors Journal compilation ª 2008 FEBS 3755 Ionic strength and magnesium affect the specificity of Escherichia ... independently evaluate the effects of ionic strength and Mg 2+ on the activity and specificity of OGG1, we measured the apparent values o...

Ngày tải lên: 18/02/2014, 18:20

... probabilistically combine ParaMor (Monson, 2008) and Morfessor (Creutz, 2006). They used a natural language tagger which was trained on the output of ParaMor and Morfes- sor. The goal was to mimic each algorithm ... PROMODES-E directly accesses the probabilistic framework of each algorithm and combines them based on an optimal threshold learnt on a validation set. 5 Co...

Ngày tải lên: 20/02/2014, 04:20

... QDs can induce signaling implicated in the response to hypoxia and can reduce the rate of fat oxidation in PC12 cells We hypothesized that QDs and CoCl 2 induce the accu- mulation of lipids in ... Nanoparticle-induced metabolic changes FEBS Journal 276 (2009) 6204–6217 ª 2009 The Authors Journal compilation ª 2009 FEBS 6209 Nanoparticles can induce change...

Ngày tải lên: 07/03/2014, 00:20

... SRE fos 5Â-d(GGATGTCCATATTA GGACAT)-3Â reproduces the sequence of the SRF recog- nition element of the c- fos enhancer [2,27]. The mut- ants SRE Gfos 5Â-d(GGATGTgCATATTAGGACAT)-3Â and SRE GGfos 5Â-d(GGATGTggATATTAGGACAT)-3Â ... ê 2007 The Authors Journal compilation ê 2007 FEBS 2339 C fi G base mutations in the CArG box of c- fos serum response ele...

Ngày tải lên: 07/03/2014, 09:20

... compilation ê 2006 FEBS 4793 Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis Ekaterina Morgunova 1 , Boris ... range. The analysis of the struc- tures demonstrated the specific features of the binding of different inhibi- tors. The comparison of t...

Ngày tải lên: 07/03/2014, 11:20

... ribonucleolytic activity and RI affinity of unactivated and activated 1C zymogen with those of other RNase A variants, we can estimate the therapeutic potential of an HCV RNase A zymogen. Unactivated 1C zymogen ... Physicochemical properties of a ribonuclease A zymogen. Ribonuclease (T m ) unactivated a ( C) (T m ) activated a ( C) (K d ) unactivated b...

Ngày tải lên: 07/03/2014, 11:20

... eukary- otic cell [22]. Therefore, we tested the effect of the replicative state of the cell on the interaction between Pol e and RNA pol II. A possible confinement of the interaction to late G 1 and S ... co-operates with polymerases a and d in the replicative DNA synthesis of eukaryotic cells. We describe here a specific physical interaction between DNA p...

Ngày tải lên: 07/03/2014, 11:20

... the DNA binding activity of dHAND could be affected by Akt phosphorylation. The influence of phos- phorylation by Akt on the DNA binding activity was examined by gel shift analysis. We included the ... phosphorylation of dHAND decreased the transcriptional a ctivity of dHAND/ E47 heterodimer. Fig. 6. The effects of A kt expression on the tran...

Ngày tải lên: 07/03/2014, 16:20

... use them as probes for exploring the active sites of enzymes, the coenzymic properties of homoadenosylcobalamins for diol dehydratase and ethanol- amine ammonia-lyase were investigated. The k cat and ... [24] and AdoEtCbl [29] were reported to be totally inactive as coenzyme for ribonucleotide reductase, and the latter inactive for diol deh...

Ngày tải lên: 07/03/2014, 21:20

... enhances shedding of syndecan- 1 through a-toxin and b-toxin [58]. Beta-toxin, but not a-toxin, also mediates shedding of syndecan- 4. Alpha- and b-toxins do not directly trigger syndecan- 1 shedding, ... full-length TIMP-1 and TIMP-3 are [31]. The C-terminal domain of TIMPs can stabilize proMMP by binding to its hemopexin domain, leaving the N-ter- minal fully capable...

Ngày tải lên: 15/03/2014, 23:20

... using the following oligonucleo- tides: NF29-F, 5Â-ttcattcatatgaccatttgaatatacaatggt-3Â; and NF29-R, 5Â-aagtaacatatgatggagaaaggacatatat-3Â. Both oli- gonucleotides carry an Nde1 site in their ... the original IVS29 context (see below). Interaction between U1 snRNP and IVS29 donor sites We then decided to investigate the ability of all these donor sites to bind U1 snRNA /U1...

Ngày tải lên: 16/03/2014, 01:20

... 5Â-GAAGTTAAAGATACAATGATTCAGCTC 5Â-GAGCTGAATCATTGTAACTTTAACTTC-3Â 48 N302D 5Â-CATTGTTGAAGACATCAATGTTG-3Â 5Â-CAACATTGATGTCTTCAACAATG-3Â 43 N302F 5Â-CTTTACATTGTTGAATTCATCAATGTTGCAGC-3Â 5Â-GCTGCAACATTGATGAATTCAACAATGTAAAG-3Â ... 5Â-CAACATTCCTTGTCATCGAACCAAACTC-3Â 58 R103M 5Â-GTTCGAGAACAATGAATGTTGTGTTC-3Â 5Â-GAACACAACATTCATTGTTCTCGAAC-3Â 55 R103E 5Â-GAACACAACATTCTCTGTTCTCGAACC-3Â 5Â-GGTTCGAGAACAGA...

Ngày tải lên: 17/03/2014, 10:20

... 2008 The Author Journal compilation ê 2008 FEBS MINIREVIEW Alternative binding proteins: Anticalins – harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding ... supported by the structurally rigid b-sandwich framework of the paired variable domains of the light and heavy chains. These CDRs come together...

Ngày tải lên: 23/03/2014, 07:20

... termed the ‘Guardian of the Genome’ [14], and so Effects of low inorganic phosphate on lung of developing mice 111 Fig. 5. Analysis of fibroblast growth factor 2 (FGF-2) protein in the lungs of ... expression in the lung [6,17]. Together, the potential importance of Pi, as a novel signaling molecule, and the pulmonary expression of NPTs together with...

Ngày tải lên: 07/08/2014, 23:22

... studies. Na 2 EDTA; induce. Acta vet. scand. 2001, 42, 251-260. Acta vet. scand. vol. 42 no. 2, 2001 Plasma Calcium, Inorganic Phosphate and Magnesium During Hypocalcaemia Induced by a Standardized EDTA ... inorganic phosphate and magnesium during hypocalcaemia induced by a standardized EDTA infusion in cows. Acta vet. scand. 2001, 42, 251-26...

Ngày tải lên: 12/08/2014, 15:20