Báo cáo khoa học: "Evaluation of the effect of a 3rd GnRH injection administered six days after the 2nd GnRH injection of Ovsynch on the reproductive performance of Japanese black cows" pps

Báo cáo khoa học: 9-Deazaguanine derivatives connected by a linker to diﬂuoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase potx

... concentration of phosphate, as indicated. For equilibrium studies, and for deter-mination of the association rate-constant, the enzyme was incubated with 1 mM phosphate and various concentrations of ... DFPP-DG and their analogues versus calf-spleen and human erythrocyte PNPs, and rates of associ-ation (k) of some of the analogues with calf spleen PNP. Kappiis an apparent inhibition constant ... a very low dissocia-tion constant (and much lower than the enzyme concentration) (i.e. the binding process stops rapidly when the added ligand concentra-tion is equal to the concentration of...

Báo cáo khoa học: Evaluation of potential regulatory elements identi®ed as DNase I hypersensitive sites in the CFTR gene doc

... 21, around 51 kb. Thelanesareasannotated in the ®gure. Lanes A and B are based on annotations from the GenBank ®le, and the DNase hyperse nsitivity sites marked in black are the experimentally ... DNase I hypersensitivity b ased on bent or easilymelted DNA. Generation of a DNA atlas for each of the t wocontigs covering the CFTR gene (ac000111 and ac000061)enabled the prediction of DNase ... and 17 (Fig. 5A) inchromatin from Capan1 cells. The DHS in i ntrons 1, 1 0a, b(very weak) and 20 were also e vident in Capan1 cells (datanot shown). Evaluation of DHS in another pancreaticadenocarcinoma...

Tài liệu Báo cáo khoa học: What makes biochemical networks tick? A graphical tool for the identiﬁcation of oscillophores ppt

... the kinetic parameters t hat enable such oscillations. The mainresult of such an analysis is that oscillations arise if t heparameter k3is the l argest and the parameters k6and k7are the smallest ... that canidentify the causes of these oscillations. These causes alwaysderive from the inﬂuences that concentrations have on reaction rates. The inﬂuences reach over many molecularreaction ... of a n even number of negativepaths a nd any number of positive paths. Our approach has the advantage th at it considers positive and negativeinteractions in a uniﬁed manner. The implication...

Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

... assubstrate in PCR with the following Ras-GRF1 gene-speci-ﬁc primers: ON3 57, 5¢-TGAAACATCACCAACTAAATCTCCAA-3¢; ON3 58, 5¢-GACGACTCCATTGTTATAGGAAAAGAGT-3¢; ON3 59, 5 ¢-GCCGCTGGAGAAACAGCAT-3¢; ON3 60, ... cleared by centrifugation (13 000 g at 4 °C) and the protein concentrations in the supernatants were quanti-ﬁed by the BC assay quantiﬁcation kit (Uptima) using BSAas the standard. Equal amounts ... A, Greenberg ME & Feig LA (1995) Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.Nature 376, 524–527.11 Mattingly RR, Saini V & Macara IG (1999) Activation of the Ras-GRF...

Tài liệu Báo cáo khoa học: "Evaluation of Machine Translations by Reading Comprehension Tests and Subjective Judgments" doc

... ments of sentence clarity, was investigated. Human translations and IBM machine translations of passages from a Russian technical journal were used as test materials. Performance on the reading ... including the two investigated here, would appear likely to be of some use. Summary and Conclusions Evaluation of the quality of machine translations by means of a test of reading comprehension and ... difficulty and question difficulty, and considerably more data would be needed adequately to separate out these effects from that of method of translation. One other aspect of the data should...

Tài liệu Báo cáo khoa học: "Exploiting Readymades in Linguistic Creativity: A System Demonstration of the Jigsaw Bard" docx

... trouvés as “assisted readymades” be-cause they allow an artist to remake the act of creation as one of pure insight and inspired recog-nition rather than one of manual craftsmanship (seeTaylor, ... course of an average day, a creative writer isexposed to a constant barrage of linguistic stimuli,any small portion of which can strike a chord as a potential readymade. In this casual inspirationphase, ... computational terms, the Duchampian notion of a readymade allows crea-tivity to be modeled not as a construction problembut as a decision problem. A computationalDuchamp need not explore an abstract...

Tài liệu Báo cáo khoa học: "Evaluation of Semantic Clusters" docx

... set of classes against an- other and are also not very reliable estimates of the quality of a set of classes. It is clear that a formal evaluation scheme would be of great help. Hatzivassiloglou ... classes of a given domain, rela- tively little attention has been paid to the task of evaluating the generated classes. In the absence of an evaluation scheme, the only way to decide if the ... Towards the automatic identifica- tion of adjectival scales: Clustering adjectives ac- cording to meaning. In Proceedings of the 31st Annual Meeting of the Association for Computa- tional...

Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

... to the amino terminal end and C2deﬁnes the domain closest to the cell membrane. A comparison of the inferred amino acid sequence of the C1 and C2 domains reveals that only the approximatespacing ... tract, gills, heartand labial palp) including female gonads (oocytes),and from various stages of embryonic and larval devel-opment (blastula, gastrula, trochophore larvae, D lar-vae, 7 and ... remained in the background of the molecular survey of metazoan development. We report the cloning and functional study of the central part of the BMP pathway machinery in the bivalve mollusc Cras-sostrea...

Báo cáo khoa học: by nucleotide afﬁnity cleavage: a distinct nucleotide speciﬁcity of the C-terminal ATP-binding site potx

... nototherwise indicated, and after an additional incubation of 15 min at 37 °C afﬁnity cleavage was induced by the addi-tion of 0.5 mMFeCl3and 30 mMascorbate and completedby an additional ... different conformation of Hsp90 than ADP oralarmones, probably because Hsp90 should adopt a thermodynamically less favored conformation to capture the ATP-c-phosphate. Diguanosine polyphosphate (GP4G)displayed ... c-phosphate binding fragment in lane 5)[20], but the application of an ATP regeneration systemrestored the usual ATP cleavage pattern (data not shown). The C-terminal domain bound each nonhydrolyzablenucleotides...

Báo cáo khoa học: "EVALUATION OF NATURAL LANGUAGE INTERFACES TO DATABASE SYSTEMS: A PANEL DISCUSSION " ppt

... EVALUATION OF NATURAL LANGUAGE INTERFACES TO DATABASE SYSTEMS: A PANEL DISCUSSION Norman K. Sondheimer, Chair Sperry Univac Blue Bell, PA For a natural language access to database system ... practical it must achieve a good match between the capabilities of the user and the requirements of the task. The user brings his own natural language and his own style of interaction to the ... beforehand, and user satisfaction afterward? IIl. On the basis of these evaluations, what should the future look like for natural language access to database? Under this point, what niches look...

Xem thêm