... gadolinium exerts its effect from the luminal side of the channel and does not penetrate to the cis side. The effect of changing cis calcium con- centration on the inhibitory effect of cis gadolinium was ... found on the cytosolic site, close to the conducting pore [10]. Results about the effect of the luminal (trans) calcium on the activity of the RyR1 are controv...
Ngày tải lên: 19/02/2014, 16:20
... MPO release under conditions in which O À 2 generation was only marginally suppressed (Fig 4). Butan-1-ol alone, up to a concentration of 3%, had no direct inhibitory effect on the MPO assay (data ... P<0.05. Results Effect of TNFa priming on O À 2 generation, MPO release, and PLD activation Before investigating the effect of TNFa priming on PLD activity, we wished t...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Effect of heliquinomycin on the activity of human minichromosome maintenance 4/6/7 helicase pdf
... ini- tiation and elongation of DNA replication [13], and these proteins migrate on the genome together with the replication forks [14,15]. One of the intricacies related to the function of the MCM2–7 ... 3. Effect of heliquinomycin on the RNA priming activity of the DNA polymerase-a/primase complex. (A) Top: effect of increasing concentrations of heliquinomycin (HQ) o...
Ngày tải lên: 23/03/2014, 04:21
báo cáo hóa học:" Effect of exacerbations on health status in subjects with chronic obstructive pulmonary disease" pdf
... limitation to our study is that unreported exacer- bations were not included [11,12,33]. Conclusion In conclusion, we demonstrated that acute exacerbations require the use of additional medication, ... prolonged study interval, then more sub- jects may have experienced exacerbations. Second, concerning the definition of an exacerbation, we selected the definition of an acute exacerbat...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo khoa học: "A Re-examination on Features in Regression Based Approach to Automatic MT Evaluation" pdf
... Gamon, and Chris Brockett. 2001. A machine learning approach to the automatic evaluation of machine translation. In Pro- ceedings of the 39th Annual Meeting of the Associa- tion for Computational ... Automatic Evaluation of Machine Translation Quality Using Longest Common Subsequence and Skip-Bigram Statistics. In Proceedings of the 42nd Annual Meet- ing of the Association...
Ngày tải lên: 31/03/2014, 00:20
Báo cáo khoa học: " Effect of the medical emergency team on long-term mortality following major surgery"
... environment [43]. Available online http://ccforum.com/content/10/2/R50 Page 5 of 9 (page number not for citation purposes) peptides only, and Stenotrophomonas maltophilia, sensitive to quinolones ... Stenotropho- monas maltophilia, sensitive to ofloxacin only. Polymicrobial wound contamination also included contamination with fungi (for instance, Candida albicans as well as non-albicans...
Ngày tải lên: 25/10/2012, 10:41
Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"
... interventions are developed that reduce consecutive work hours to ensure the safety of patient care. We believe, however, that development of ‘a sense of professionalism’ is not a function of whether ... intervention took place in a system that was designed to minimize the impact of hand-offs, which by definition occurred more frequently in the intervention schedule. Even with t...
Ngày tải lên: 25/10/2012, 10:45
Tài liệu Báo cáo khoa học: Effect of siRNA terminal mismatches on TRBP and Dicer binding and silencing efficacy pdf
... Effect of siRNA structure and composition on siRNA–protein complexes We wished to examine further the impact of terminal mismatches and also selected internal mismatches on the interactions of ... depen- dence of silencing, to ensure that the differences among the siRNAs that we observed at 10 nm were within the dose-responsive concentration range (Fig. S1). Effect of TR...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr docx
... P-loop conformation is stable over a broad ionic strength range. Structure of PhyAsr upon oxidation of the catalytic cysteine A systematic comparison of the open P-loop confor- mation in PhyAsr to ... 1U24. Oxidation of cysteine affects the conformation of several residues The P-loop conformational change is primarily due to a large shift in the / ⁄ w torsion angles in Ala254 (/...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx
... Ig-b locus. Acetylation of H3 and H4 histones in cells deleted in region II Acetylation of H3 and H4 histones is enhanced in and around potentially active and transcribed genes A BC Fig. 2. Construction of DT40 ... deletion (16 kb Del) in one allele of the Ig-b locus (Fig. 1). Introduction of the 16 kb Del construct into DT40 ⁄ Cre cells resulted in two deletion clones. In one...
Ngày tải lên: 19/02/2014, 16:20