Báo cáo khoa học: "Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat" pdf

... ingredients (milk thistle extract, green bean-rice bran fermentation extract) and turnip concentrate. The herbal extract mixture preparation included the following: 100 g of the xylem and bark ... liver injury in the rats studied. To determine the precise mechanism underlying the efficacy of the herbal extract mixture for ethanol toxicity, studies focusing on the antioxidant effects of the ... that the herbal extract mixture had a protective effect against ethanol-induced toxicity in a mouse model [1]. In this study, the herbal extract mixture and yogurt also showed protective and therapeutic...

Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf

... parameters of TOP and neurolysinactivities on Qf7 were also determined in the presence of 2MNaCl. In this condition, the Eyring plots obtained forTOP and neurolysin gave two linear ﬁttings, above and below ... TOP and neurolysinTable 1 shows the kinetic parameters of the hydrolysis byTOP and neurolysin of the substrates on the series Abz-GGFLRRXQ-EDDnp and their peptide bonds cleaved in the kinetic ... TOP and neurolysin activities The in uence of NaCl concentration on kcat/Kmvalues of TOP and neurolysin activities on the peptides containingAla, Val, Asp and Ile at the X position in the...

Tài liệu Báo cáo khoa học: Temperature and phosphate effects on allosteric phenomena of phosphofructokinase from a hibernating ground squirrel (Spermophilus lateralis) pptx

... °C; in fact, the addition of inorganic phos-phate resulted in an inhibition of PFK activity. Fur-ther analysis of phosphate effects on PFK at 5 °Cseemed warranted and Fig. 1 shows an anomalousinteraction ... ligand and not by changes in the extent to which the binding of allosteric ligandmodiﬁes the afﬁnity of enzyme for substrate. The Hanes–Wolf plot in Fig. 3(B) conclusively demon-strates that the ... protein. Anal Biochem 104, 130–135.31 Bradford MM (1976) A rapid, sensitive method for the quantiﬁcation of microgram quantities of protein util-izing the principle of protein-dye binding. Anal...

Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt

... searches of b-amino acids wereinitially carried out at intervals of 30° for each torsion angle/, h,andw and were subsequently reﬁned by varying /, wangles in intervals of 10° and setting h angle ... [3H]propionyl[Met(O2)11]SP(7–11) and associated with the production of inositol phosphates. The binding and agonist potencies of the SP analogues areFig. 3. Chemical shift deviations of Ha (A) and Ca (B) for the SP analogues ... in blue, oxygens in red, hydrogens in grey. Carbon atoms of Pro are coloured in cyan, those of other amino acids in green. The side chain methyl carbon of b-HAla and the pro R methyl carbon of...

Báo cáo khoa học: "Immunomodulatory and antitumor effects in vivo by the cytoplasmic fraction of Lactobacillus casei and Bifidobacterium longum" pot

... Bifidobacterium, immunopheno-typing, in vivo, survival rateIntroduction The enhancement of the gut mucosal barrier may prevent the invasion of pathogens and assist in handling antigens.Lactic acid ... Differential effects of viable and killed bacteria. Clin Exp Immunol. 1979, 37, 367-375.2. Bogdanov IG, Popkhristoveand P, Marinov L. Anti cancereffect of Antibioticum bulgaricum on Sarcoma-180 and the solid ... increased with long-term feeding of LABs, and thiscan be one of factors for the improved antitumor immunity in this study.Though the mechanism on different degree of antitumoractivity against...

Báo cáo khoa học: "Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats" ppsx

... lesions in the seminiferous tubules. There were thickening and multiple layering of the tubular endothelium, and the formation of many multinucleated giant cells in seminiferous tubules. Taken together, ... isolated from the vehicle control rat (A) and the acrylamide (60 mg/kg/day)-treated rat (B). Thickening and multiple layering of the tubular endothelium (arrow), and the formation of many multinucleated ... of acrylamide showed histopathological changes in the seminiferous tubules (Fig. 5B). There were thickening and multiple layering of the tubular endothelium, degeneration of germ cells, and the...

Tài liệu Báo cáo khoa học: "Liars and Saviors in a Sentiment Annotated Corpus of Comments to Political debates" pdf

... Wilson, and Claire Cardie. 2005. “Annotating expressions of opinions and emo-tions in language”. In Language Resources and Eval-uation, volume 39, 2-3. Wilson, Theresa, Janice Wiebe, and Paul Hoffmann. ... definite descrip-tions and nicknames. 1 Introduction Most of the existing approaches to opinion mining propose algorithms that are independent of the text genre, the topic and the target involved. ... annotated. The annotation was per-formed at word and phrase level, and the sentiment expressions identified in the corpus were asso-ciated to the source of the private-state, the target involved and...

Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of ﬁve novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx

... main chain nitrogen and main and side-chain oxygen atoms of Ala59 and Glu61 of one subunit and with the main chain nitro-gen of Asn114¢ of the other subunit. The contacts of the ribityl chain to ... values can be used for comparison of bindingafﬁnities of the inhibitors under study. The ﬁtting of the binding isotherms of all ﬁve com-pounds with a binding model assuming identical and independent ... atoms of the pyrimidine ring and the protein chain. Namely, there are two new directhydrogen bonds formed between carbonyl oxygen O1 and the main chain Ala59N and between N1 and Val81O. Four other...

Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

... receptors are in bold and underlined, and the cysteine knot is boxed.Also boxed are the transmembrane domain, the ATP binding site, the L45 loop and the serine ⁄ threonine kinase domain. (B) The implied ... alsoshown in bold and the cysteine knot isboxed. The C1 and C2 domains appeared tobe joined by a ‘linker’ sequence. Also boxedare the transmembrane domain and the serine ⁄ threonine kinase domain.A. ... C1 deﬁnes the domain closest to the amino terminal end and C2deﬁnes the domain closest to the cell membrane. Acomparison of the inferred amino acid sequence of the C1 and C2 domains reveals...

Báo cáo khoa học: Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells pptx

... and bandsSC3a and SC3b appeared (lane 12). Coaddition of the twoantibodies resulted in the loss of bands C1, C2, and C3 (lane13). In contrast, the use of a control monoclonal antibody against ... Sp1 and Sp3 are able to bind to the GCboxes and that binding of Sp1 forms complex C1 and binding of Sp3 forms complexes C2 and C3.PMA treatment increases Sp1 and Sp3 proteinexpression in HL-60 ... detected. The intensity of the 105 kDa band was signiﬁcantlyincreased in the PMA treated cells than in the control cells,whereas that of the 95 kDa band was not changed(Fig. 5A). Using anti-Sp3...

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