Báo cáo khoa học: "Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats" ppt

... Changes of biomarkers with oral exposure to benzo(a )pyrene, phenanthrene and pyrene in rats 365 Fig. 5. Changes of PAHs and their metabolites in urine at different time points by treatment with ... sul- Changes of biomarkers with oral exposure to benzo(a )pyrene, phenanthrene and pyrene in rats 367 present study, BaP and its metabolite, 3...

Ngày tải lên: 07/08/2014, 20:23

... plasmid combinations were spotted either onto medium lacking histidine and leucine to select for the plasmids, or onto medium lacking histi- dine, leucine and uracil to monitor protein interactions. ... The split-ubiquitin system. The N-terminal and C-terminal halves of ubiquitin (N-Ubi and C-Ubi) alone do not assemble. If a protein ‘X’, fused to N-Ubi, binds to the PAKs Ste...

Ngày tải lên: 18/02/2014, 13:20

... correct value to be used in rela ting dosi- metric indices with treatment outcome [5]. To analyze and study the anatomical changes of lung parenchyma due to radiation therapy, and to calculate ... loss and in patient 1 because of mediastinum shift (Table 2). Furthermore patient 1 presented a mediastinum shift during the course of therapy and an increasing atelec- t...

Ngày tải lên: 09/08/2014, 09:20

... of 3.04 and a F A of 0.44, and was concluded to consist mainly of DDA and DAA, in addition to minor amounts of ADA. The tetramer fraction showed a DP of 4.1 and a F A of 0.33 and the dominant tetramers were ... by adding 5 lgof ChiB and was stopped after between 15 and 10 080 min by adjusting the pH to 2.5 with 1.0 m HCl, and immersing the samples in bo...

Ngày tải lên: 07/03/2014, 16:20

... form favorable interactions with the substrate. In the bind- ing of G6, Phe313 mainly interacts with the six mem- bered ring of Glc–3, while in the binding of P2, it makes contact with the C6 atoms of Glc–2 ... Glc–1 of G6 to bind to subsite )1 more deeply than that of P2. This may be caused by Fig. 5. Stereoview of the catalytic site of D356N ⁄ P2. The binding...

Ngày tải lên: 16/03/2014, 14:20

... 5¢-end of the ATT-template) folding into a hairpin-like structure. The double helix of the hairpin stem, stabilized by the binding of DAPI into the minor-groove of AÆTandTÆTbase-pairs, appears to ... observable fluorescence band and a change in electrophoretic mobility due to the drug binding. This is attributable to the property of DAPI that favours folding of the random...

Ngày tải lên: 16/03/2014, 23:20

... impact of RNA binding on pro- tein structure and substrate-binding ability. Proteins that bind and process nucleic acids are often capable of binding to both RNA and single- stranded or double-stranded ... an intrinsic relationship between the RNA binding and protein folding in RNA–UDE. Interestingly, treatment of RNA–UDE with RNa- se A did not result in significant chang...

Ngày tải lên: 22/03/2014, 16:21

... immunopre- cipitate, indicating that the interactions of these differ- ent proteins are likely to be indirect, depending on the presence of intact RNA as integral component of the RNP. Association of 42Sp50 with ... shuttling protein with a function in the nuclear export of localizing mRNAs. To determine whether 42Sp50 is capable of shuttling, we injected the radioactive...

Ngày tải lên: 23/03/2014, 03:20

... cells found inefficient membrane insertion of GPIba transfected as a single-chain and secretion of a glycocalicin-like s oluble form. The exact m echanism l eading to release of GPV into t he culture ... will be important in the perspec- tive of determination of its 3-D s tructure, the mapping of ligand domains such as the sites interacting with collagen and the mechanism...

Ngày tải lên: 23/03/2014, 13:20

... to treatment with JH alone. Subordination of JH III signaling through USP to status of EcR activation There remains the question of why overexpression of EcR, leading to increased formation of ... been presented showing the ‘sub- ordination’ in vivo of RXR to the liganded state of RAR arises from the inability of RXR ligand to effect dislodging of corepressor [...

Ngày tải lên: 23/03/2014, 13:20