Báo cáo khoa học: "Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes" pdf

Ngày tải lên: 07/08/2014, 20:23

... blotting. Fig. S1. Expression of neural retina Nrl mRNA. Fig. S2. Generation of the polyclonal antibody for Nrl and expression of Nrl proteins in various cell lines. Fig. S3. Efficiency of Nrl ... with the goal of determining the critical stage for Nrl-mediated Ppp2r5c expression. Results Conserved sequences of the Ppp2r5c promoter contain Nrl-binding sites In the searc...

Ngày tải lên: 06/03/2014, 02:20

... The Transactions of The Insti- tute of Electronics, Information and Communication Engineers, J77-D-II(5):1028-1030. T. Kohonen. 1990. The self-organizing map. In Proceed- ings of IEEE, volume ... muc-r. In Proceedings of MUCS, pages 147-159, August. A. Okumura, T. Ikeda, and K. Muraki. 1997. Selec- tive dissemination of information based on a multiple- ontology. In Pr...

Ngày tải lên: 31/03/2014, 04:20

... Solid line: the case of kinase sequestration, dotted line: no kinase sequestration. Grey lines indicate the stimu- lus (i.e. kinase concentration), scaled by 0.1 in (A). Effects of sequestration ... concentration and total kinase concentration, respectively, and K M is the Michaelis–Menten constant of the kinase. The con- centration of the complex [TK] approaches the total concentra...

Ngày tải lên: 19/02/2014, 07:20

... secretion [6]. Addi- tionally, arginine methylation regulates cytokine gene transcription in T helper (Th) cells through arginine methylation of the NFAT cofactor, NFAT interacting protein 45 ... effectiveness of compound 4 on PRMT1 inhibition was dependent upon the substrate used, with methylation of GST–GAR being more responsive to inhibition than histone 4. A histone 4 and an arg...

Ngày tải lên: 06/03/2014, 11:20

... results for a common query. Indexing millions of search logs and listings can be done in minutes. Reusing text search engines allows a seamless integration between query parsing and search. We ... using an h- gram model on the concept sequence as shown in Equation 3. We model the segment sequence generation probability P (S|C) as shown in Equa- tion 4, using independence assumptions...

Ngày tải lên: 08/03/2014, 21:20

... an increase in TQ concentrations did not lead to enhanced inhibition. Supported by the literature [30], we propose that this U-shaped inhibition depends on the presence of an additional binding ... TQ concentrations of 5 and 20 lm, whereas it decreases at a concentration of 100 lm (corresponding to the recovery of proteasome activity). At the same time, increases in TQ concentra...

Ngày tải lên: 15/03/2014, 11:20

... this is not considered to be of great importance and could be a result of differences in the active enzyme concen- tration. The effect of changing residues in the helicase domain on inhibition was ... hydrogen bond donor, interacting with the carbonyl oxygen of the P4 residue on the inhibitor, or as a hydrogen bond acceptor for the P4 NH of the inhibitor. Although some of...

Ngày tải lên: 16/03/2014, 06:20

... is not surprising, considering the location of these changes. Glycine 157 is in one of the loops that moves on binding of sub- strate and divalent cation. This loop contains histidine 159, which ... position would result in a change in the conformation of this loop. Changes in the conformation of the backbone at this point and changes in the orientation of other side c...

Ngày tải lên: 16/03/2014, 06:20

... concen- trations or low temperatures, the gain in entropy on release of ions is reduced and substrate binding is therefore weaker [33]. This makes binding of highly charged DNA very challenging ... substrate binding and dissociation rate constants, as found in the cold adaptation of cod trypsin [39], or, in the case of VsEndA, may be linked in some way to cold adapta- tion,...

Ngày tải lên: 16/03/2014, 06:20