Báo cáo khoa học: " Diversity of swine Bordetella bronchiseptica isolates evaluated by RAPD analysis and PFGE" docx

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Ngày tải lên: 07/08/2014, 20:23

... through modulation of RGS1 and RGS2. The molecular mechanisms, leading to this modulation and the consequences of the modulation of RGS1 and RGS2 remain to be investigated. Materials and methods Reagents Dulbecco’s ... modulation of RGS1 and therefore the regulation of different proteins is enforced by RGS2 mRNA after 12 h of stimulation. The upregulation of both RGS...

Ngày tải lên: 18/02/2014, 13:20

... bottom of the binding site by its d-Trp3 group and stabilized by the formation of six hydrogen bonds: a bidentate hydrogen bond between O d1 and O d2 of Asp147 (TMH III) and the nitrogen atom of ... oxygen of d-Pro2 and O c1 Thr218 of 2.69 A ˚ , a situation common also to compound 5, sta- bilized by the formation of two hydrogen bonds between O c1 Thr218 and OPro...

Ngày tải lên: 23/03/2014, 07:20

... with outer segments of photo- receptors through i ts large numbers of villi, and is involved in phagocytosis of shed outer segments [1] and in uptake, processing, and transport of retinoids [2]. ... level of HO-1 is reduced in those RPE cells under certain conditions, we a nalyzed the effects of i nterferon-c and hypoxia, each of which represses the expression of HO-1 m...

Ngày tải lên: 23/03/2014, 13:20

... RNAi-mediated depletion of both U2AF 35 a and U2AF 35 b isoforms in HeLa cells altered alternative splicing of Cdc25 transcripts [55]. Sequence comparisons of U2AF 35 splicing isoforms and U2AF 35 -related ... functions are often acquired through gene duplication events, followed by the evolution of specialized gene functions, as well as by the creation and loss of differe...

Ngày tải lên: 23/03/2014, 10:20

... family. CvMT-I and CvMT-II gene expression is induced by cadmium The expression of CvMT-I/II isoforms in gill and hepato- pancreas, and their upregulation by exposure to copper, zinc and cadmium, ... mutation of a lysine codon introduces a stop codon in CvMT-II isoforms. (A) Diagram of CvMT-I and -II isoform structural diversity, as represented by cDNA. (B) Conceptual t...

Ngày tải lên: 30/03/2014, 13:20

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Ngày tải lên: 07/08/2014, 20:23

... stochiometry of 1 : 1 of dTTP bound per subunit of dCTP deaminase. Mutational analysis of amino acid residues involved in dTTP regulation of dCTP deaminase The design of the mutant enzymes H121A and V122G was ... site had partly col- lapsed caused by a movement of the lip formed by a helix 2 and b strand 5 [18]. Apparently, movement of the active site lip prevented b...

Ngày tải lên: 18/02/2014, 16:20

... fractioned by electro- phoresis and detected by immunoblot analysis, using a polyclonal anti-Rho (-A, -B, -C), Cdc42 and Rac1 Igs. Total RhoA, Cdc42 and Rac1 in each lysate were determined by western ... dynamics Ibrul Chowdhury 1, * and Brahim Chaqour 2 1 Department of Anatomy and Cell Biology, University of Pennsylvania, PA, USA; 2 Department of Anatomy and Cell Bio...

Ngày tải lên: 19/02/2014, 16:20

... produced by th e interaction of the metal with a unique site present in t he reductase domain of the enzyme [13]. This domain binds one equivalent of FMN and one of FAD and, members of t he Fd–NADP(H) ... for appropriate binding of the metal ion, which remains accessible from the exterior (Fig. 7B). Distances between the N5 and O4 of the flavin, O of Ser90, S of Cys266...

Ngày tải lên: 19/02/2014, 16:20