... residues and mechanism of UDP-glucose dehydrogenaseXue Ge1, Lisa C. Penney1, Ivo van de Rijn2and Martin E. Tanner11Department of Chemistry, University of British Columbia, Vancouver, Canada;2Wake ... M. E. Tanner, Department of Chemistry,University of British Columbia, 2036 Main Mall, Vancouver,British Columbia, Canada V6T 1Z1.Tel.: +1 604 822 9453, Fax: +1 604 822 2847,E-mail: mtanner@chem.ubc.caAbbreviations: ... roles of other key activesite residues via mutagenesis studies were hampered by an inability to isolate several of the mutants (Lys204Ala,Asn208Ala, and Asp264Asn) in a soluble form. Of the...