Báo cáo khoa học: "Cellular uptake of magnetic nanoparticle is mediated through energy-dependent endocytosis in A549 cells" pptx

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Báo cáo khoa học: Cellular uptake of antisense oligonucleotides after complexing or conjugation with cell-penetrating model peptides pdf

... cases and also in the lysates of the CHO-cells. In the lysates of the LKB-Ez7cells on the other hand partial splitting of the disulﬁde bond in the cell interior throughout the 30 min incubation ... (Table 1) fromalanine-glycine replacement (II), uniform distributionaround the helix of the lysines (III, Fig. 1) or both (IV)were included in the investigations in order to obtaininformation about ... complexes of the 15-mer PTO withall peptides, including the Antennapedia sequence V,administered in this manner led to 20–50% reduced viabilityafter this treatment. Sixfold administration of 0.1...

Báo cáo khoa học: "Site adaptations of Acanthogyrus (Acanthosentis) tilapiae: Observations through light and scanning electron microscopy" pptx

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Báo cáo khoa học: "Weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: analysis of data rom randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01)" pdf

... staining; 1–4, weak staining; 5–8, moderate staining;and 9–12, strong staining. For the purpose of statisticalanalysis, the cohort was grouped into tumors with negli-gible or weak staining ... and cisplatin. Of the 221 patients, 88 were referred for treatment from asingle institution following initial diagnosis of NPC. Forlogistic reasons, only patients from this hospital wereincluded ... wasused to determine the level of COX-2 expression. A singlehead and neck histopathologist was assigned to performthe scoring. She was blinded to all patient characteristicsincluding the treatment...

Báo cáo khoa học: "Canopy uptake of N deposition in spruce (Picea abies L. Karst) stands" pdf

... foundlower NH4+ and NO3-fluxes in throughfall than in rain,suggesting uptake of the N by the canopy. Higher Nfluxes in throughfall than in bulk precipitation have oftenbeen reported at strongly ... canopydevelopment of the stand [5]. With the objective of estimating the total depositionand canopy uptake of N, we established a number of plastic Christmas trees in clearings of the catchment ... mostmineral elements, has generally increased from rain tothroughfall and this increase has been related to standage. This relation with stand age has been hypotheticallylinked to an increase in...

Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc

... d-amino acid oxidase [47]. In B. subtil- is, GO is involved in biosynthesis of the thiazolemoiety of thiamine pyrophosphate (vitamin B1). Thisreaction requires the direct transfer of the imine ... substrate amine. This substrate-assisted proton transfer mechanism is consistent with the observed pH dependence of kcat, and explains the dual role of His138 in substrate binding and as a catalytic ... activity is accompanied by improved bind-ing to longer ligands (up to ﬁve atoms in the mainchain) and retained binding to shorter ligands [55]. Of the 21 changes in the evolution of R7 fromnative...

Tài liệu Báo cáo khoa học: Subproteomics analysis of Ca2+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle pdf

... expression of this important luminalCa2+-binding protein is changed in an established animalmodel of d ystrophinopathy.DiscussionMuscular dystrophy refers to a group of hereditary diseasescharacterized ... protocols maydistort comparative immunoblotting data, it was of interestto re-examine the fate of cals equestrin by studying the entirecomplement of key Ca2+-binding elements in dystrophin-deﬁcient ... expression of majorCa2+-binding proteins in dystrophic ﬁbres. A comparisonbetween the selective d ye labelling of protein spots in Fig. 3showed that 11 main protein spots a re recognized in normalﬁbres...

Tài liệu Báo cáo khoa học: Quantitative estimation of channeling from early glycolytic intermediates to CO2 in intact Escherichia coli pdf

... wouldresult in unchanneled ﬂux even if every intermediatejust made in the pathway remained within the putativecomplex. Finally, if channeling is being assessed bymeasuring the isotopic composition of ... are inherently unsatisfying. In particular, chan-neling is thought to be the result of protein–proteininteractions in the crowded, organized environment of the cell. Although investigators sometimes ... channeling is the degree to which theFru6P just made in the pathway is disproportionatelysuccessful in being the substrate for PFK. Invoking theusually proposed mechanism for channeling, the...

Tài liệu Báo cáo khoa học: "The impact of language models and loss functions on repair disﬂuency detection" pptx

... of Speech Disuencies. Ph.D. thesis, University of Cali-fornia, Berkeley.David A. Smith and Jason Eisner. 2006. Minimum RiskAnnealing for Training Log-Linear Models. In Pro-ceedings of the 21st International ... probing for thelocation of the best analysis in a 100-best list. Thisexperiment shows that in 99.5% of the cases the bestanalysis is located within the ﬁrst 25, and indicatesthat an f-score of ... motivating the channel model design is that the words inserted into the reparandum arevery closely related to those in the repair. Indeed, in our training data we ﬁnd that 62% of the words in the...

Tài liệu Báo cáo khoa học: Functional dissection of the Schizosaccharomyces pombe Holliday junction resolvase Ydc2: in vivo role in mitochondrial DNA maintenance pptx

... study of the role of recombination in mtDNA inheritance in S. cerevisiae showed that buddingcells were enriched in linear monomers of mtDNA. It wasproposed that in addition to a role in initiating ... [14,20]. Binding of CCE1 results in thecomplete unpairing of the four base-pairs in the centre of the junctions with a lesser disruption of the next base-pairs[19], which is reminiscent of the ... lacking leucine in thepresence of thiamine for inhibition of the nmt promoter. Forvisualization of Ydc2–GFP constructs, yeast cultures weregrown in selective media in the absence of thiamine...

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