Báo cáo khoa học: "Changes of gastrointestinal argyrophil endocrine cells in the COLO205 tumor-implanted Balb/c-nu/nu mice" pps
Ngày tải lên: 07/08/2014, 18:21
... technique, the Grimelius method. The general distribution of the argyrophil cells in the GI tract F ig. 1. Argyrophil endocrine cells in the GI tract of sham; Most of argyrophil cells were dispersed in ... their density would reflect the change in the capacity of producing these hormones [8]. In the present study, the changes of the argy...
Ngày tải lên: 07/08/2014, 17:23
... helix–span–helix domain at the C-terminus shown in blue medi- ates dimerization and, together with the basic domain, (red) DNA-binding. ‘*’, amino acids that are identical in all sequences in the align- ment; ... tried to link the expression of AP-2a in these tissues to upstream signaling pathways. They assessed the organization of a cis-regulatory region within the fif...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx
... receptor-blocking experiments. The rates of uptake of both the lipid and protein components are not matched by the rate of cel- lular metabolism of these species, resulting in the accu- mulation of both ... glycation, rather than purely the loss of the parent amino acid, which is the key factor in terms of receptor recognition [29]. There are no data available...
Ngày tải lên: 19/02/2014, 02:20
Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt
... those with the C-terminal domain deleted is consistent with this (Figs 4 and 5). Hybrid proteins carrying the N-terminus of one protein and the Sm domain of the other localize according to the N-terminal ... the latter, indicating that in the absence of an N-terminal domain distinct localization is lacking. Finally, the Lsm1p Sm domain by itself (LsmDN1DCp) accumu- lat...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Interaction of human stefin B in the prefibrillar oligomeric form with membranes Correlation with cellular toxicity doc
... By following the kinet- ics of fibril formation, conditions were defined in which the protein exists in the form of prefibrillar oligomers ⁄ aggregates, which persist during the lag phase. These have ... content of negatively charged phospholipids in the outer mem- brane lipid leaflet. Insertion in monolayers The ability of stefins and their aggregates to insert at the...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of b-lactam antibiotics pptx
... the kinetic constants for hydrolysis and synthesis of penicillin G, ampicillin and cephalexin. Furthermore, insight into the nature of the transition state in the rate-determining steps of the ... 7). The V s /V h ratio is the ratio of the reaction rates of aminolysis and hydrolysis of the acyl-enzyme. The curva- ture of the plot of V s /V h vs. the m...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Characterization of N-glycosylation consensus sequences in the Kv3.1 channel pot
... glycosy- lation of the native site in the S1–S2 linker was required for proper trafficking and stability [43]. On the other hand, glycosylation of the native site in the S1–S2 linker of Kv1.0s, including ... fractionation proto- col involved reducing the starting material and the volume of the sucrose layers but maintaining the relative ratios of the sucrose l...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: Interactions of ultraspiracle with ecdysone receptor in the transduction of ecdysone- and juvenile hormone-signaling pdf
... receptors, including human RXR (which is the ortholog of USP) have shown that an area on the surface of the ligand binding domain involving the C-terminus of a-helix 3, a-helix 4, and the N-terminus of ... integrate the JH III-signaling. We therefore postulate that during the integra- tion of action of JH III and 20OHE to activate DR1JHECore transcription in Sf9 c...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf
... partition method. In the first stage, the hydrophylic upper phase contained the total original activity of the peroxidase inhibitor. In the second stage of the purification, 70% of the inhibitory activity ... concentration in the medium, concomitantly with the disappearance of the GPX activity in the same conditions. The presence of insulin or anyone o...
Ngày tải lên: 30/03/2014, 14:20