Báo cáo khoa học: "Idiopathic intranuclear inclusion bodies in the renal tubular epithelia of Japanese quail (Coturnix coturnix japonica)" pot

... we found two cases of idiopathic intranuclear inclusion bodies in the renal tubular epithelia among the 960 Japanese quail ( Coturnix coturnix japonica ) in the course of the acute oral toxicity ... Japan) at an accelerating voltage of 80 KV. The intranuclear inclusion bodies were detected in the tubular epithelia of two cases of among...

Ngày tải lên: 07/08/2014, 18:21

... substrate carbinolamine intermediate; III, iminoquinone intermediate; IV, product Schiff base intermediate; V, aminoquinol intermediate. In the oxidative half-reaction the ami- noquinol intermediate ... kinetically in uential ionizations were identified in plots of k lim ⁄ K d of pK a values 7.1 and 9.3, again with the maximum value realized in the alkaline region. The pot...

Ngày tải lên: 19/02/2014, 07:20

... described for the sulfuration of the C-terminal glycine in ThiS and MoaD, involved in thiamine biosynthesis and molyb- dopterin biosynthesis, respectively, and for the sulfura- tion of uridine in tRNA ... methylases [9]. How the sulfur is transferred into the carboxamide group of glycine in the peptide chain remains to be shown. Neither the functions of the five...

Ngày tải lên: 16/03/2014, 05:20

... separately fitting domains I and II to the structure of DcP. The identification of the appropriate clipping points was aided by using the Alternate Domain Fit tool from the suite of tools within the swiss-pdbviewer ... 611) in the loop, particu- larly Gly603, in maintaining the plasticity of the active site and the full range of function of TOP. Most recently...

Ngày tải lên: 23/03/2014, 06:20

... bonding between the imidazole nitrogen of the conserved His and the hydroxyl of the active-site Ser increases the nucleophilicity of the Ser oxygen, facilitating attack of the hydroxy group on the ... 2B). A closer view of the axial canal in the center of the spicule reveals local- ization of silicatein in the axial filament as well as within the sil...

Ngày tải lên: 18/02/2014, 16:20

... Ca 2+ peak) resulted in an almost immediate abolition of the remaining part of the Ca 2+ signal, which then reached the level as in platelets preincubated with AR-C. In the experiments, a concentration of 2–5 ... that neither wortmannin nor TGX221 affected thrombin generation in the pres- ence of AR-C (not shown). With only wortmannin present, the PKA inhibitor H89...

Ngày tải lên: 18/02/2014, 16:20

... take into account the variability of the length of the complete domain, the length of the N-terminal fragment was definned as the length of the amino acid sequence preceding the next domain in the ... domain deletions are more com- mon at either of the protein termini, and that their occurrence is slightly higher at one of the termini, depending on the num...

Ngày tải lên: 19/02/2014, 07:20

... Nexø, E. (1991) Effect of the cobalt-N coordination on the cobamide recognition by the human vitamin B 12 binding proteins intrinsic factor, transcobalamin and hapto- corrin. Eur. J. Biochem. 199, ... at the internal site …PSNPflGPGP. The key properties of the preparation obtained were identical to those of native IF: the binding curves of vitamin B 12 to recombinant IF an...

Ngày tải lên: 21/02/2014, 00:20

... of our art? Instead of assuming that the problem is one of using typed English to access and/or update a file or files in a single database system, let us define a spectrum of potential natural ... and mine it very deeply, not necessarily discovering every aspect of the domain but requiring that the various aspects be integrated with one another to produce a coherent...

Ngày tải lên: 21/02/2014, 20:20

... of increased prolifera- tion or recruitment of preadipocytes [12], suggesting that these cyclin-dependent kinase inhibitors are important in the regulation of adipocyte number. The S-phase kinase-associated ... a deficiency in Skp2, the substrate-binding subunit of the SCF Skp2 complex, contributes to the degradation of p27 Kip1 , resulting in an induced resistance to...

Ngày tải lên: 06/03/2014, 01:20