Báo cáo khoa học: "Molecular analysis of hprt mutation in B6C3F1 mice exposed to ozone alone and combined treatment of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate for 32 and 52 weeks" ppsx
... such dominant transversion may be responsible for toxicity and combined exposure to ozone, NNK, and DBP induces additive genotoxicities compared to ozone alone. Key words: Ozone, NNK, DBP, hprt mutation Introduction Ozone ... 1. DNA sequence analysis of hprt mutant in splenic cells of B6C3F1 male mice in 52- wk study Type of mutation Number of...
Ngày tải lên: 07/08/2014, 18:20
... RC, Davis AF & Tornehl CK (1998) Delineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagmin. J Biol Chem 273, 329 66 329 72. 51 Nakatani ... This amino-acid motif mimics RGD in terms of charge and is positioned at the tip of a loop and is therefore reminiscent of RGD sequences present in integrin-binding molecule...
Ngày tải lên: 30/03/2014, 11:20
... expressed in these serotonin receptor- expressing tracheolar cells and if serotonin is in any way involved in modulating water transport in tracheolar cells. Hormonal regulation of mammalian AQP1 and ... 20mininPBSTGandincubated in a 1 : 750 dilution of biotinylated anti-rabbit IgG (Vector Laboratories) for 1 h. Tissues were washed 4 · 20 min in PBSTG and incubated in...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: "A Re-examination on Features in Regression Based Approach to Automatic MT Evaluation" pdf
... Albrecht and Rebecca Hwa. 2007. A Re- examination of Machine Learning Approaches for Sentence-Level MT Evaluation. In Proceedings of the 45th Annual Meeting of the Association of Com- putational Linguistics ... Simon Corston-Oliver, Michael Gamon, and Chris Brockett. 2001. A machine learning approach to the automatic evaluation of machine translation. In Pro- ceedin...
Ngày tải lên: 31/03/2014, 00:20
Báo cáo khoa học: Molecular cloning, expression analysis and functional confirmation of ecdysone receptor and ultraspiracle from the Colorado potato beetle Leptinotarsa decemlineata pdf
... difference in receptor-binding affinity of DBHs among insect orders might rather be attributed to the amino acid residues which are considered to be involved in binding to both types of ligands. Amino ... successfully performed cDNA cloning of EcR and USP of L. decemlineata, and in vitro translation of corresponding receptor proteins. The translated proteins could bin...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis Functional analysis of the promoter identifies a calcium sensitive region required for basal activity doc
... MGP and all other members of this vitamin K-dependent protein family can bind to mineral and, in particular, calcium- containing-mineral such as hydroxyapatite [2]. Although the exact m ode of ... the fragments of interest (spanning the regions )648 to +44, )464 to +44, )185 to +44, )949 to )326 , and )949 to )708, respectively) were blunt ended andinsertedattheSmaI s...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Molecular cloning and characterization of the crustacean hyperglycemic hormone cDNA from Litopenaeus schmitti Functional analysis by double-stranded RNA interference technique pot
... RNase-free water. Single-stranded RNAs were allowed to anneal by mixing equal amounts of each strand, heating to 100 °C for 1 min, and cooling gradually to room temperature for 3–4 h. Single-stranded RNAs and ... including the fore gut site. Recently, CHH was reported in the endocrine cells of the fore gut and hind gut of Carcinus immediately prior to and during mo...
Ngày tải lên: 23/03/2014, 10:20
Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc
... optimization for glyphosate activity is accompanied by improved bind- ing to longer ligands (up to five atoms in the main chain) and retained binding to shorter ligands [55]. Of the 21 changes in the ... Gene shuffling improved the designed enzyme 200-fold to 400-fold [65], illustrating the advantage of combining tools for enzyme optimiza- tion. With the increasing demand...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx
... overexpression, parkin and PTEN-induced putative kinase 1 loss -of- function and UCHL1 mutation, lead to an impairment of neuronal dopamine homeostasis by interfering with the vesicular storage and release mechanisms. ... [1–6]. Single point mutations in a-synuclein, as well as duplication and triplication of the gene, were reported to be linked with rare familial forms of...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt
... blot analysis was performed to investigate the expression profile of the BmIVD gene. For both wild-type and sku strain, a single band of 1.35 kb, cor- responding to the predicted molecular size of ... cycling consisted of 40 cycles of denaturing at 94 °C for 30 s, annealing at 54 °C for 30 s and extension at 72 °C for 90 s. 5¢- and 3¢-rapid amplification of cDNA...
Ngày tải lên: 18/02/2014, 04:20