Báo cáo khoa học: "Seroprevalence of Antibody to Procine Reproductive and Respiratory Syndrome Virus in Diagnostic Submissions" ppsx

Báo cáo khoa học: Binding of hemolin to bacterial lipopolysaccharide and lipoteichoic acid An immunoglobulin superfamily member from insects as a pattern-recognition receptor doc

... hemolin may be due to binding and crossing-linking of these micro-organisms by hemolin.Binding of hemolin to bacteria and yeast cellsM. sexta hemolin was reported to b ind to E. coli [23] and to enhance ... Gram-positivebacteria, inhibited hemolin binding to LPS by 86%.LTA was more effective than LPS itself as an inhibitor of hemolin binding to LPS, suggesting that LPS and LTAbindtothesamesitesonhemolinandthathemolinmay ... hemolin binding to S-LPS byapproximately half and nearly eliminated hemolin binding to lipid A. An interpretation of these results is thatphosphate disrupts binding of lipid A by competing for...

Tài liệu Báo cáo khoa học: Exposure of IgG to an acidic environment results in molecular modiﬁcations and in enhanced protective activity in sepsis doc

... role of hydrophobicity in the binding of a pH 4.0 buffer-treated monoclonal IgG antibody to its target antigen To evaluate the types of intermolecular interactions in antigen binding, pH and salt ... buffer resulted in an increase in its pre-existing binding to antigens present in anEscherichia coli lysate, and in the appearance of somenew bands showing the acquisition of new antibody reactivities ... Increased binding of low-pH buffer-exposed IVIg to human factor H. In both panels, binding of the native IVIg is indicated by a solid line, and that of the low-pH buffer-exposed IVIg is indicated...

Tài liệu Báo cáo khoa học: "Integration of Speech to Computer-Assisted Translation Using Finite-State Automata" pdf

... Using this approach,the number of identical paths in MT and ASRword graphs are increased to 39.7% and 34.4% of the sentences in development and evaluationsets, respectively. The WER of the integratedsystem ... acceptor form in two differentways:1. a linear acceptor, i.e. a sequence of nodeswith one incoming arc and one outgoing arc,the words of source language text are placedconsecutively in the ... (OOV) words.The remaining part of the XEROX corpus is used to train a back off trigram language model us-ing the SRI language modeling toolkit (Stolcke,2002). The LM perplexity of the speech recogni-tion...

Báo cáo khoa học: Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivation ppt

... expresses[3H]cGMP-binding activity and that Pc inhibits[3H]cGMP binding to Pabc. We also show that thecGMP binding to Pabc is suppressed during Pabccactivation, i.e. cGMP binding is not involved in Pabccactivation. ... PabcNext, we investigated whether cGMP binds to Pabcduring deactivation of Pabc to Pabcc. Binding of cGMP may be involved in Pabc deactivation in twoways: after interaction with Pc and before interactionwith ... FEBS In conclusion, Pc appears to suppress [3H]cGMPbinding to Pabc by interrupting the entry of [3H]cGMPinto a noncatalytic site in Pabc. This indicates that thescheme in which Pc binds to...

Báo cáo khoa học: Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells docx

... of the TOP1inhibitor, camptothecin, in the presence and in theabsence of 10)5m MTX. The cytotoxic effect of camptothecin alone was enhanced by the addition of the concentration of MTX to which ... down-regulating vimentin in the absence and in the presence of MTX. Targeting of vimentinwas carried out by lipofecting aODN-VIM into paren-tal HT29 cells causing a decrease of 60% in theexpression of ... (IUPUI, Indianapolis, IN, USA), or the TOP1 inhibitor camptothecin (Sigma,Madrid, Spain), in the presence or absence of MTX. IMPDHactivity inhibitors were added simultaneously to MTX.Camptothecin,...

Báo cáo khoa học: Binding of berberine to human telomeric quadruplex – spectroscopic, calorimetric and molecular modeling studies pot

... 3981interaction of berberine with quadruplex. The occur-rence of sharp isobestic points at 359, 383 and 445 nmclearly indicates the existence of equilibrium in thebinding. Ligand binding with ... with aninteraction that provides valuable insights into the type and magnitude of forces involved. Therefore, we haveutilized ITC to characterize the thermodynamics of binding of berberine to quadruplex. ... still be used to accurately and directlymeasure the binding enthalpy and stoichiometry forthis interaction. ITC remains an invaluable techniquefor determining binding enthalpies, even in cases...

Báo cáo khoa học: Existence of novel b-1,2 linkage-containing side chain in the mannan of Candida lusitaniae, antigenically related to Candida albicans serotype A potx

... Existence of novel branched side chains containingb-1,2 and a-1,6 linkages corresponding to antigenic factor 9 in the mannan of Candida guilliermondii. J. Biol. Chem. 271,9259–9266.18. Tojo, M., ... series of absorbed factor sera. ÔCandida CheckÕ, a commerciallyavailable kit containing 10 factor sera is an effective tool foridentifying the cells of Candida species in clinical specimens.Candida ... contained b-1,2-linked mannose units; no a-1,3 link-ages or a-1,6-linked branching points were found in the sidechains. An enzyme-linked immunosorbent inhibition assayusing oligosaccharides indicated...

Báo cáo khoa học: "Compilation of HPSG to TAG*" pptx

... the bottom of the domination link and identification of the root with top of the domina- tion link. Since the domination link at the root of the adjoined tree mirrors the properties of the ... first adjoining the tree T6 at the topmost dom- ination link of T5 we obtain a structure T7 corre- sponding to the substring what to give to Sandy. Adjunction involves the identification of the ... fill in the details below in the following order: what information to raise across domination links (where adjoining may take place), how to de- termine auxiliary trees (and foot nodes), and...

Báo cáo khóa học: Fidelity of targeting to chloroplasts is not affected by removal of the phosphorylation site from the transit peptide doc

... preproteins, directing them to ribosomes in closerproximity to mitochondria [32]. Also in fungi, the acidity of Tom22 at the mitochondrial surface is thought to provide abinding site for basic mitochondrial ... motif for binding of 14-3-3 proteins, and 14-3-3 proteins were shown to bind to the phosphoserine/phosphothreonine site en route to thechloroplast envelope [14], although before import into thechloroplast ... and with isolatedchloroplasts. In this case, the precursor is imported into chloroplasts and processed to the size of GFP alone. (C) and (D) Incubation of GFP fused to the two mutant forms of...

Báo cáo khoa học: "Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial"

... monitoring (no monitoring, wrong drug mon-itoring, if necessary according to normal hospital practice).7. Route of administration (incorrect route, route omitted).8. Infusion rate of continuous ... The inci-dence of minor MPEs decreased from 18.3% in the PB-U to 0.7% in the C-U, since completeness and legibility of the orderwas mandatory in the CPOE part. However, a missing infusionrate ... case of vancomycin prescriptions, physicians had to ordera 'vancomycin loading dose' and a 'vancomycin dose accord-ing to plasma level', without having to adjust anything,...

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