Báo cáo khoa học: "Pim-1 A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis" potx

...

Ngày tải lên: 07/08/2014, 15:20

... idea that G154 plays a structural rather than an enzymatic role: the mutant G15 4A is still active as a kinase, suggesting that it can bind ATP. Indeed, the K d of this mutant protein for ATP was ... HPrK/P with an alanine resulted in a large reduction in kinase activity, although the affinity for ATP was not significantly affected [29]. G207 is located in asmallb-sheet, and...

Ngày tải lên: 16/03/2014, 16:20

... sequences of BapA from strain 3-2W4, Pseudomonas sp. strain Y2 and DmpA from Ochrobactrum anthropi. Identical amino acids are marked in black and similar amino acids are marked in gray. The cleavage sites ... isoleucine and tyrosine with all possible combinations of a- amino acids and b-homoamino acids were used as substrates for 3-2W4 BapA (A D) and Y2 BapA (E–H). No degrada...

Ngày tải lên: 30/03/2014, 10:20

... the amount of training data has when using the CLASS BASED and MAXENT methods by initially train- ing each system with just the Brown and Switch- board corpora and testing on WSJ. Then we incre- mentally ... corpora into training and testing data. For each NP in the test data, we gener- ated a set of modifiers and looked at the predicted orderings of the MAXENT,CLASS B ASED, a...

Ngày tải lên: 30/03/2014, 21:20

... Combinatory Categorial Grammar. In Proceedings of the 6th Inter- national Workshop on Tree Adjoining Grammars and Related Frameworks (to appear), Venice, Italy. Michael Collins. 1996. A new statistical parser ... Seattle, WA. David Chiang. 2000. Statistical parsing with an automatically-extracted Tree Adjoining Grammar. In Proceedings of the 38th Meeting of the ACL, pages 456–463, H...

Ngày tải lên: 31/03/2014, 06:20

... grammar. An exam- ples is: S ~ al S S~al A1 S-+anS S-+anAn A~ -+ a~ X A2 + al A2 An -~ al An X-+e A1 -+ a2 Az A1 ~ an A1 A2 -+ a2 X A2 ~ an A2 An -+ a2 A, ~ An ~ an X Here the grammar ... Finite-state calculus A 'finite-state calculus' or 'finite automata toolkit' is a set of programs for manipulating finite-state automata and the regular lang...

Ngày tải lên: 31/03/2014, 21:20

... the atmospheric conditions prevailing during this short peri- od, the main unfavourable factors being rain and wind. Rainy weather, unfortunately frequent during the pollination ... one can rarely take advantage of the early and later hours of the day which would allow a longer working period. Effective harvesting generally takes place between 11...

Ngày tải lên: 08/08/2014, 23:22

... repair factor XP -A gave a compar- able staining pattern (data not shown). Pol e detected with antibody G 1A showed the punctuate staining typ- ical for nondamaged cells also at the damaged areas (Fig. ... genetically with mcm5 mutants and showed adverse effects on minichromosome maintenance and DNA replication [19]. Whereas other DNA repair and replication factors interacting...

Ngày tải lên: 07/03/2014, 11:20

... State ap- proach (Traum and Larsson, 2003). GoDiS has been adapted to several different dialogue types, do- mains, and languages, including menu-based mul- timodal dialogue when acting as an interface ... of advanced dialogue applications. 92 Staffan Larsson and Jessica Villing. 2009. Multimodal menu-based dialogue in dico ii. In Jens Edlund, Joakim Gustafson, Anna Hjalmarsson, and...

Ngày tải lên: 07/03/2014, 22:20

... modular MCA for large responses is that the C w v coefficients can be calculated in an alternative way, using data obtained by modulating S and measuring the resulting rates. In this approach, values ... S-adenosyl-L-methionine synthetase 3 gene. Plant J 29, 371–380. 29 Heremans B & Jacobs M (1995) Threonine accumulation in a mutant of Arabidopsis thaliana (L.) Heynh. with an a...

Ngày tải lên: 14/03/2014, 23:20