Báo cáo khoa học: "Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis" pdf

... 53–58 Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis Woo-song Ha 1 , Chi-kyeong Kim, Seung-hee Song and Chung-boo Kang* Department of Internal Medicine, ... 21]. In the present study, the development of a hepatocar- cinogenesis model involved the administration of adminis- tering only water containing 0.01% DEN for...

Ngày tải lên: 07/08/2014, 14:23

... elicits innate immune responses in macrophages, RT-PCR and ELISA assays were used to examine induction of transcriptional gene upregulation and increased expression of proinflammatory cytokines. ... was examined by measuring the  max of congo red-polysaccharide solutions at NaOH concentra- tions ranging from 0.01N to 0.5N. Polysaccharide aqueous solutions (1 mg/ml) containing 100 ␮l...

Ngày tải lên: 28/06/2014, 11:20

... clinical examination based on clinical signs of the HF. Whole parts of the body of horses were clinically examined for the presence of nodules, ulcers along the lymphatic vessels, on the skin ... station was visited four times in two separate days: twice per day, in the morning and in the afternoon in order to examine the two shifts of horses of each cart. 2.3. Clinica...

Ngày tải lên: 07/08/2014, 15:20

... production of inter- leukins and secretion of immunoglobulins on the mucosal surface of the intestine [49,50]. The antibacte- rial defence of the intestinal mucosa depends in part on stimulation of ... (s) concentration–response curves in mouse splenocytes. Splenocytes were exposed to increasing concentrations of CCK-8, or a single concentration of CCK-8-NS in the pres...

Ngày tải lên: 19/02/2014, 16:20

... N-terminal domain harboring activation function 1, a central DNA-binding domain (DBD) and a C-terminal ligand- binding domain (LBD) containing activation func- tion 2 [67–70]. Upon binding androgens, ... transcription. In addition, actin is required for the initiation of transcription through par- ticipation in the formation of PICs [17]. These conclu- sions are based on the followi...

Ngày tải lên: 07/03/2014, 01:20

... nature of the involvement of GAPDH and the CAG expansion of the mutant huntingtin protein. One such scenario is that the interaction between poly- glutamine-containing proteins and GAPDH results in a ... optimization of the assay conditions), the concentrations could only be determined at two time points (35 and 120 min). In line with our expectation, we found the total concentrat...

Ngày tải lên: 23/03/2014, 10:20

... the indolamine serotonin (5-HT) in uence a variety of behaviors in invertebrates through their actions as neurotransmitters, neurohormones and/or neuromodulators [1,2]. In insects, these monoamines ... a-glucuronidase; 5-HT, serotonin; NE, norepinephrine; NET, norepinephrine transporter; OA, octopamine; OAT, octopamine transporter; ORF, open reading frame; SERT, serotonin transporter;...

Ngày tải lên: 23/03/2014, 20:22

... concentration (bicinchoninic acid reagent; Pierce). Splicing of modified first intron Constructs carrying the different modules of the GS first intron were tested for proper splicing of the mRNA. RT-PCR ... MODEL/ ANOVA without interaction ( SPSS version 10.0.7; SPSS Inc.). The activity of a specific construct (X,Y) containing upstream module (X) and intron module (Y) can be modelled to c...

Ngày tải lên: 23/03/2014, 20:22

... remarkable consistency of the develo- ping body plan. In 1942, Conrad Waddington put forward the concept of canalization, referring to the invariance of the wild-type phenotype in the face of genetic ... extensively in the Dro- sophila wing imaginal disc. Scaling is maintained upon mutations in components of the insulin-signaling path- way, which alter tissue size by affecti...

Ngày tải lên: 30/03/2014, 02:20

... carrying out the post-translational modification of the C-terminus of the large subunit [29,30] during the maturation of the stable HynSL hydrogenase in T. roseo- persicina. Cotranscription of hupK and hypC 1 DE The ... the processing of the HupL subunit [15]. It is plausible to assume that HynD is involved in the maturation of the HynL protein. Indeed, in the strain harborin...

Ngày tải lên: 31/03/2014, 01:20