... Ca 2+ . Removing the proposed Ca 2+ -coordinating residues in positions 1 and 3 of the EF-hand motif significantly compromised the metal-binding capability of the engi- neered protein, indicating that the ... grafting approach to address this question. As shown in Fig. 1B, the distance between the two termini of the inserted Ca 2+ -binding sites in the model str...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: "Teratological effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): induction of cleft palate in the ddY and C57BL/6 mouse" pptx
... gestation day for the induction of cleft palate when TCDD was administered per oral. Gross and histological morphology The cleft palates induced in the fetuses of C57BL/6 and ddY mice treated ... expression of AhR in the craniofacial tissue between the two mouse strains, since AhR mediates the induction of cleft palate by TCDD and its level may...
Ngày tải lên: 07/08/2014, 14:23
... re- quirement by Kintsch and Vipond (1979) and Kemper (1983), who both insist on the impor- tance of including the conceptual properties of texts (such as the relations between propositions and the “inference ... (2) where p(t i ) is the probability of meeting the token t i in French; and n is the number of tokens in a text. 2. Deciding what is the best lin...
Ngày tải lên: 08/03/2014, 21:20
Báo cáo khoa học: " Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors" docx
... deleterious effects of radiosurgery may be offset by the early beneficial effects of smoking cessation [25]. Ninety-five percent of the patients in the current trial discontinued smoking in the distant ... distribution (B: the planning treat-ment volume is shown in orange and the 30 Gy isodose line in blue), and CT at 6 and 12 months post-treatment (C and D)...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo khoa học: Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain pdf
... lupin enzyme and of 2.1 lm (3) and 2.5 lm (4) for the human counter- part. These K i values lie in the range of the K m values for Ap 4 A: 2.5 lm for the narrow-leaved lupin [25] and 2 lm for the ... in the a,b active site. Taken together, the results of cleavage of compounds 3 and 5 show that the asymmetrically acting Ap 4 A hydro- lases can reach the sc...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation ˆ Benoıt Palancade and Olivier Bensaude pptx
... degeneracy of the CTD adds a further level of complexity (Fig. 1). Indeed, the N-terminal half of the CTD only stimulates capping whereas the C-terminal half supports capping as well as splicing and ... CDK1 and CDK2 phosphorylate both serine 2 and serine 5 [41,44]. Efficiencies of the different kinases are in uenced by the position of the targeted repeats within...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx
... different from that of other relaxin proteins involved in the growth and remodeling of reproductive and other tissues during pregnancy [10]. In the mouse and rat brain, relaxin-3 expression was reported ... including the stress response and food intake, are described. Expression of relaxin-3 in the brain Relaxin-3 neurons in the brain Examination of relaxin-3...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: "general overview with a seasonal assessment silver fir forest in the Vosges mountains (France)" docx
... strong inhibi- tion of cytokinines synthesis and transloca- tion also reinforces the inhibition of the root system development (Pan et al, 1989); iv) alteration of the root ... Aluminium determina- tion in soil solution. I. Evaluation of existing colorimetric and separation methods for the determination of inorganic monomeric alu- minium in...
Ngày tải lên: 08/08/2014, 19:21
Báo cáo khoa học: " Stereotactic radiosurgery may contribute to overall survival for patients with recurrent head and neck carcinoma" pptx
... 5:51 http://www.ro-journal.com/content/5/1/51 Page 3 of 9 ment. Treatment was administered depending upon the configuration and volume of the tumor as determined by the treating radiation oncologist, neurosurgeon and oral and maxillofacial ... the clinical target volume without the addition of any margin, corresponding to the 80-85% isodose contour. In the cases o...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats ppt
... curcumin and capsaicin significantly inhibited the in vivo iron-induced LDL oxidation, as well as copper-induced oxidation of LDL in vitro. The protective effect of the combination of curcumin and ... LDL oxidation in the case of LDL isolated from animals fed the combination of curcumin and capsaicin. Thus, the protective effect of the combination of...
Ngày tải lên: 08/03/2014, 08:20