Báo cáo khoa học: "Activation domain in P67phox regulates the steady state reduction of FAD in gp91phox" pot

... determine the domain in p67 phox which is essential for regulating the steady state of FAD reduction. The minimal length of p67 phox for for regulating the steady state of FAD reduction is shown ... 5695-7. Activation domain in p67 phox regulates the steady state reduction of FAD in gp91 phox 29 (Table 1). The steady state percent...

Ngày tải lên: 07/08/2014, 14:22

... HT22 cells, to further examine the binding of Nrl to the Ppp2r5c promoter in vivo. Nrl binding to the Ppp2r5c and rhodopsin promoters was examined by quantitative real-time of ChIP samples with ... during photoreceptor development when compared with the patterns of binding of Nrl to the rhodopsin promoter (Fig. 4C,D). The mRNA tran- script levels of Ppp2r5c and rhodops...

Ngày tải lên: 06/03/2014, 02:20

Ngày tải lên: 07/08/2014, 18:21

... loss of the ability to regulate transferrin binding (Fig. 7B). By contrast, cells transfected with either the single or double mutants were all capable of reducing transfer- rin binding. In each ... interactions with b2 microglobulin (b2M) [4,5,8–11]. In the absence of b2M binding, the protein misfolds and is retained in the endosplasmic reticulum (ER) where it induces a...

Ngày tải lên: 06/03/2014, 22:21

... dHAND, we next examine whether the DNA binding activity of dHAND could be affected by Akt phosphorylation. The in uence of phos- phorylation by Akt on the DNA binding activity was examined by gel shift ... phosphorylation Interestingly, major phosphorylation sites of dHAND are located within the bHLH domain. Therefore, we speculated that phosphorylation of these sites might...

Ngày tải lên: 07/03/2014, 16:20

... technique for enforcing the non-overlapping constraint discussed in Section 3.1. The labeling of the tree in Figure 1 is a specific example of the kind of errors fixed by the joint mod- els. The local classifier ... to the maximum of: • The sum of the log-probabilities of the most likely assignments of the children subtrees t 1 , . . . , t k plus the log...

Ngày tải lên: 08/03/2014, 04:22

... distinguished in this respect" verbs like eat are capable of m-incrementality, i.e., incrementality with individual-referring delimiting arguments (they have an incremental themes in the sense of ... discussing the accessibility of the internal structure of delimiting argument NPs ; I suggested a solution to the problems raised by the polysemous internal stru...

Ngày tải lên: 08/03/2014, 06:20

... comprised of an N-terminal kinase domain, a calmodulin-binding domain, eight ankyrin repeats, two nucleotide binding domains (P-loops), a cytoskeleton binding domain and a C-terminal death domain. ... kinase-related apoptosis-inducing protein kinase 1) and DRAK2 [1]. DAPK is a large 160 kDa serine ⁄ threonine protein kinase composed of several functional domains includ- ing a kinase...

Ngày tải lên: 28/03/2014, 23:20

... explored the ability of human cath- epsins B, K and L to participate in the production of kinins, using kininogens and synthetic peptides that mimic the insertion sites of bradykinin on human kininogens. Although ... that cathepsin K is a new member of the kininase family. Both the kininogenase activity of cathepsin L and/or the kininase activity of cathepsin K may b...

Ngày tải lên: 31/03/2014, 07:20

... implementation of independently motivated linguistic-theoretic descriptions. The informing principles are those of modern 'lexicalist' unification-based linguistic theories: the English ... presentation is also being refined. Foundations in linguistic theory We are committed to active recognition of the mutual benefit of machine translation and linguistic the...

Ngày tải lên: 01/04/2014, 00:20