... to the identification of the second siderophore (data not shown). We therefore assume that either the extraction conditions were inadequate for the iso- lation of the natural product, or that the ... characterization of these compounds is growing and may result in the synthesis of specific inhibitors based on the structure of the pathogen siderophore [16]. A promisin...
Ngày tải lên: 16/02/2014, 09:20
... ion mass spectrum of the doubly charged ion at m ⁄ z ¼ 660.18. The isotopic distribution of the b 2 ion (inset) indicates the presence of bromine. The MS ⁄ MS spectrum allows assignment of the sequence SW*NCYNGHCTG, ... immedi- ately adjacent to the N-terminal signal peptide [7,14– 17]. The propeptide mediates binding of the substrate to the carboxylase and also...
Ngày tải lên: 23/03/2014, 11:20
Báo cáo khoa học: A Kazal prolyl endopeptidase inhibitor isolated from the skin of Phyllomedusa sauvagii pdf
... for each concentration of the inhibitor by nonlinear fit of the data from the above negative controls; [I] is the concentration of the inhibitor, IC 50 is the concentration of inhibitor that causes ... at least one of these enzymes. Although the serum proteases tested in the assay are unlikely to be the natural targets of PSKP-1, they are representative of its...
Ngày tải lên: 30/03/2014, 13:20
báo cáo hóa học: " Different gait tasks distinguish immediate vs. long-term effects of concussion on balance control" ppt
... through proper positioning of the CoM and momentum of the CoM over the base of support has been established as a measure of dynamic balance control [20,21]. In this study of walking balance control, ... work clearly points out the importance of fur- ther investigation of the complex issue of balance control following concussion. Competing interests The authors decl...
Ngày tải lên: 19/06/2014, 08:20
Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx
... under- neath the spectrum) provide sequencing data from the N-terminal end of the peptide. The positive ion mass spectrum (Fig. 3) provides the majority of the sequence except that it does not identify the ... combination of the fragmentation data from the negative and positive ion spectra give the full sequence of eugenin (for sequence, see Table 1). Synthesis...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc
... analysis of the las operon been shown to take place at the transcriptional level [15]. Deletion of the entire pyk gene from the las operon resulted in a slight disturbance in the relative levels of ... analysis of the las operon FEBS Journal 272 (2005) 2292–2303 ª 2005 FEBS 2293 minute. The relative values of simultaneous modulation of the three las enzymes are c...
Ngày tải lên: 19/02/2014, 17:20
Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf
... later than in the case of the histone gene cluster [10]. This difference in the tim- ing of somatic pairing perhaps reflects the difference between the complexities of the regulation of the two systems: ... approach their proper target promoter in the viscous environment of the nucleus. Somatic pairing of chromosomes and the regulation of Abd-B A peculiarity...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo khoa học: Cyclic ADP-ribose requires CD38 to regulate the release of ATP in visceral smooth muscle ppt
... facilitated the EFS-evoked release of ATP. Further studies are needed to determine the mechanisms of purine-mediated presynaptic neuromod- ulation in the bladder. The enhancing effect of cADPR on the ... must, then, be present in this preparation. Of particular importance is the finding that exogenous cADPR failed to increase the spontaneous release of ATP in the abse...
Ngày tải lên: 05/03/2014, 23:20
Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx
... liganded AR to the nucleus. In the nucleus, FLNa(16–24) disrupts interactions between the N- and C-termini of the AR, and interferes with the binding of the coactivator TIF2 [86,91]. There is evidence ... attenuates the coregulator activity of SV. There are two possible explanations for this: (a) the accumulation of SV in the membrane prevents it from associating w...
Ngày tải lên: 07/03/2014, 01:20
Báo cáo khoa học: Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus potx
... P i . The effect of these samples on cyto- kine production by PBMCs activated by LPS was then assessed as described above. Prediction of interaction sites The prediction of binding sites from the ... meal from a variety of verte- brates, ranging from amphibians to mammals, and including domestic animals and humans [2]. It is the one of the vectors of Borrelia burgd...
Ngày tải lên: 07/03/2014, 01:20