... cytochrome P450s. All activated carcinogens can bind to DNA and form DNA adducts that are capable of inducing muta- tions and initiating carcinogenesis. The capacity to repair DNA damage induced ... essen- tial for the two incision steps in NER. The ERCC5/XPG nuclease has been suggested to act on the single-stranded region created as a result of the combined action...
Ngày tải lên: 31/10/2012, 14:59
... using the motion vectors of adjacent blocks [9, 10]. Spatial error concealment methods restore the miss- ing blocks only based on the information decoded in the cur- rent frame. To restore the ... frames using the prediction based on the statistical model is better than the one obtained by setting to zero the coefficients correspond- ing to the lost subband. Note a...
Ngày tải lên: 23/06/2014, 01:20
Báo cáo khoa học: "Language ID in the Context of Harvesting Language Data off the Web" ppt
... word tokens in the language lines) available, and 45.3% of the languages have no more than 10 word tokens in the training data. • The length of test instances: The language lines in IGT are often ... be- tween the token lists built from the current IGT with the ones built from other IGTs in the same document. If some IGTs in the same document share the same t...
Ngày tải lên: 31/03/2014, 20:20
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine. The triad of hypersensi- tivity includes fever, rash and internal organ involvement with onset of symptoms within 1 to 8 ... oxcarbazepine (Trileptal), phenytoin (Dilantin and others), pimozide (Orap), quetiapine (Seroquel), risperidone (Risperdal), sibutramine (Meridia), thioridazine (Mellaril and othe...
Ngày tải lên: 25/10/2012, 10:51
Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression profiling ppt
... recovered, only the longest amino acid sequences that included the DNA binding, hinge and ligand-binding domains were used for this analysis, except for the Knirps fam- ily members that lack the LBD. In D. ... to the protein synthesis inhibitor Chx. This observation could be explained by a stabilization of pre-existing mRNAs [53,54,77] or due to Chx inhibiting the expressi...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Electrostatic contacts in the activator protein-1 coiled coil enhance stability predominantly by decreasing the unfolding rate docx
... interpretation in distinguish- ing interacting from noninteracting proteins. One Fig. 1. Schematics of library designs. The helical wheel diagram looks down the axis from the N-terminus to the C-terminus. ... tangible oppor- tunity to inhibit protein–protein interactions and there- fore prevent and sequester proteins involved in pathogenic events. For example, the coiled...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Final steps in the catabolism of nicotine Deamination versus demethylation of c-N-methylaminobutyrate doc
... expect them also to be expressed in a nicotine- dependent manner. In order to investigate this, we analyzed the transcription of these genes in the pres- ence and absence of nicotine in the growth ... the sample formed a white protein pellet and a yellow supernatant, showing that the flavin cofactor was not covalently bound to the protein and thin layer chromato...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Isochore structures in the chicken genome ppt
... f denotes the first point occurring during the course of segmentation, and l and r denote that the point occurs in the left and right subsequence, respect- ively. The integer denotes the times ... shown in Fig. 2, the domains obtained can delineate the variations of the cumulative GC profile and the density distribution of CpG islands more and more accurately w...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Oxidative stress in the hippocampus after pilocarpineinduced status epilepticus in Wistar rats doc
... pilocarpine, on muscarinic and dopaminer- gic receptors and on phosphoinositide metabolism in rat hippocampus and striatum. Neurochem Int 33, 299–306. 21 Viana GSB, Marinho MMF, Sousa FCF, Bruin VMS, Aguiar ... probably uses other scav- enging systems (catalase and GSH). Pilocarpine-induced SE produces several changes in variables related to the generation and elimination of...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase Structure of the reduced enzyme-progesterone complex and the roles of residues Tyr186, His181 and His184 pdf
... unusual in having two histidine residues (rather than the His-Asn pair seen in OYE, MR and some of the other member proteins; Fig. 1B) in the active site for ligand and substrate binding. For ... productive binding of steroid substrates: in the first, a (small) sub population of enzyme binds directly the steroid in the reactive conformation, with the remainder of t...
Ngày tải lên: 20/02/2014, 02:21