Báo cáo lâm nghiệp: "Evaluation of the growth and health status of selected clone mixtures in comparison with ordinary planting stock" docx
báo cáo hóa học:" Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma" docx
... participated in the study design and coordination. TLW carried out and inter- preted the immunoassay and drafted portions of the man- uscript describing the assays. WG participated in the design of the ... environment include injection of the cytokine intratumorally [17] and administering intratu- moral injections of adenovirus encoding IL2 [18]. In the l...
Ngày tải lên: 18/06/2014, 15:20
Tài liệu Báo cáo Y học: The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168 pdf
... mixture of GM1a and GM2 core types with the GM2 core type mimic predominating. Comparison of LOS core structures of NCTC 11168 (HS:2) with the HS:2 serostrain indicated that both the terminal galactose ... 5127 N-acetylhexosamine is in the furanose configuration. It is interesting to note that loss of GalfNAc, one of the three main sugars in the polymer repeat...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Purification, characterization, immunolocalization and structural analysis of the abundant cytoplasmic b-amylase from Calystegia sepium (hedge bindweed) rhizomes ppt
... the first amino acid the residue preceding this methionine is shown in lower case. The sequence corresponding to the N-terminal sequence of the protein is underlined. The arrowheads indicate the positions ... for the b-amylase from C. sepium using the X-ray coordinates of the soybean b-amylase (Fig. 4). According to the Ramachandran plot of this model the f and...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo khoa học: Identification, subcellular localization and functional interactions of PilMNOWQ and PilA4 involved in transformation competency and pilus biogenesis in the thermophilic bacterium Thermus thermophilus HB27 ppt
... implicated in retraction of the PilA4-comprising DNA translocator transporting the DNA through the periplasmic space. Binding of the DNA to the DNA-binding protein ComEA on the surface of the inner ... one of the oldest branches of bacterial evolu- tion and, together with the genus Deinococcus, form a distinctive group within the Bacteria deserving the tax...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: The enantioselectivities of the active and allosteric sites of mammalian ribonucleotide reductase pptx
... interactions, with decreased affinity mainly resulting from loss of the interactions with the ribose, e.g. in the s-site, between a specific Asp (D232 in eR1, D226 in mR1) and the ribose 3¢-OH. In the presence ... we examine the enantioselectivity of the allosteric and substrate bind- ing sites of murine ribonucleotide reductase (mRR). l-ADP binds to the ac...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo Y học: Functional studies of the Synechocystis phycobilisomes organization by high performance liquid chromatography on line with a mass spectrometer docx
... significant decrease in the total intensity of the stained bands, confirming the h igh sensitivity of the HPLC method (inset A of Fig. 4). Nevertheless, Fig. 4 (inset B) shows the time course of spectroscopic ... disintegration of the rod complexes. The two bilins present in b-phycocyanin give a greater contribution to the UV absorption than the s ingle bilin of...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc
... deduced using the combined information of the intensities of J ab couplings from the 2D DQF-COSY spectrum and the NOE intensities of the HN-H b and H a -H b cross peaks from the 2D and 3D NOESY ... in Fig. 4, dimerization of RIIa D/D is main- tained by strong hydrophobic interactions of side chains that form the core of the protein at the dimer interface....
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity potx
... Thermus thermophilus and 30–36% identity with OATs from other species [15,16]. OAT is one of the enzymes involved in the biosynthesis of arginine from glutamate, in which ornithine is a key intermediate (Scheme ... the widely used amino-acid acylases [34], in particular for the resolution of racemic mixtures of certain amino acids with side chains containing pola...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo khoa học: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism pptx
... Dehydroepiandrosterone inhibits the prolifera- tion of HUVEC by enhancing the expression of p53 and p21, restricting the phosphorylation of RB, and is androgen- and estrogen-receptor independent. ... be interesting to determine whether other proteins that control the cell cycle are involved in the effects induced by DHEA in cervical cancer. It has been suggested that...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus ppt
... domains, followed by a peri- pheral subunit-binding domain (PSBD) responsible for binding E3 in the majority of organisms. In icosahe- dral complexes, the PSBD is also involved in the bind- ing of ... describes the interaction of a 15 N-labelled PSBD (residues 119–171) of the B. stearothermophilus E2p polypeptide chain with the dimer of a protein domain (E3int) r...
Ngày tải lên: 16/03/2014, 18:20