Báo cáo sinh học: "Robust and specific inhibition of microRNAs in Caenorhabditis elegans" doc

... specific inhibition of lys-6 miRNA in the ASEL neurons, where it functions to maintain left-right symmetry. is technique also successfully demonstrated the inhibition in activity of miR-42, ... example, progeny of animals injected with antisense oligonucleotides against lin-4 show delayed exit in differentiation of seam cells and lack of vulva formation, known phen...

Ngày tải lên: 06/08/2014, 19:21

... rminal and a C- terminal region of CIITA interacting with the viral transactivator, although, as stated above, only the N- terminal region is involved in the inhibition of Tax-2 function. Interestingly, ... molecules was analyzed in the presence and in the absence of CIITA. In the absence of CIITA, Tax-2 localizes both and in the cytoplasm and in the nucleus of...

Ngày tải lên: 18/06/2014, 22:20

... doctors in training. BMJ (Clinical research ed 2001, 323:1266. 38. Benes V: The European Working Time Directive and the effects on training of surgical specialists (doctors in training): a position ... Implementation of the European Working Time Directive in neurosurgery reduces continuity of care and training opportunities. Acta neurochirurgica 2010. 42. Bohra AK: Traini...

Ngày tải lên: 18/06/2014, 17:20

... 3 of 4 CASE STUDY Open Access Profile and professional expectations of medical students in Mozambique: a longitudinal study Paulo Ferrinho 1,2* , In s Fronteira 1,2 , Mohsin Sidat 3 , Fernando ... (Faculty of Medicine of the University Eduardo Mondlane (MF-UEM), in Maputo, and Faculty of Health Sciences of Lúrio Uni- versity, in Nampula) and the Catholic University i...

Ngày tải lên: 18/06/2014, 17:20

... also be helpful in deciphering the role of residues 190 and 246 of the HA molecule in receptor binding specificity and transmission of these viruses between swine and turkeys. Interspecies transmission ... MDCK cell line maintained in Opti-MEM minimum essential medium (Invitrogen, Grand Island, NY) containing 0.5 μg/ml trypsin. The samples were passaged twice in MDCK cells...

Ngày tải lên: 18/06/2014, 18:20

... require new ways of thinking and the help of mathematicians and physicists. These approaches are being incorporated into the broad field of ‘systems biology’. To help the application of this tech- nology ... families to investigate cytoskeletal function in Drosophila S2 cells. They targeted dynein and all 25 Drosophila kinesins to investigate the role of molecular motors dur...

Ngày tải lên: 06/08/2014, 18:20

... binding domain of DPK3-scFv, it is reasonable that DPK3-scFv can directly interfere the phos phorylations of DNA-PKcs, including site of S2056, which, in some extent, results in a deficient of ... comparisons. Results Identification of antigen fragment of DNA-PKcs DNA-PKcs is approximately 470 kD consisting of 4128 amino acids. Its C-terminus contains a serine/threonine prot...

Ngày tải lên: 09/08/2014, 09:20

... between the number of rRNA gene copies and staining intensity; NORs having a small number of the genes can express more intense staining than NORs containing many rRNA genes ... the inheritance of silver-stained nucleolus organizer regions. Hum Genet 41, 181-187 Martin-DeLeon PA, Fleming ME, Petrosky DL (1978) Patterns of silver staining in...

Ngày tải lên: 09/08/2014, 18:21

... segregation of loci or the two loci with the largest effect were linked with a recombination rate of 0.1. In the case of linkage, linkage phase of the parents was either random ... polygenic value increases with an increase in the relative magnitude of dominant loci over all polygenic loci. In addition, with dominance, the genetic var...

Ngày tải lên: 09/08/2014, 18:22

... describing direct and indirect effects of GSH in growth control of H37Rv in blood cultures derived from healthy and HIV-infected subjectsFigure 6 Model describing direct and indirect effects of GSH ... in three out of six subjects (Fig 1b). Treatment of HMDM with NAC at 5 mM and 15 mM induced growth inhibition of H37Rv, in one out of six, and two out of six...

Ngày tải lên: 10/08/2014, 05:20