Báo cáo sinh học: "Q&A: What can microfluidics do for stem-cell research" ppsx

... Biology 2010, 9:1 http://jbiol.com/content/9/1/1 doi:10.1186/jbiol220 Cite this article as: Csete M: Q&A: What can microfluidics do for stem-cell research? Journal of Biology 2010, 9:1. Page ... of the microenvironment, and information from experi- ments can be fed back into mathematical models to determine optimal design features to promote specific stem-cell behaviors. G...

Ngày tải lên: 06/08/2014, 19:21

... used every means of informing himself about questions that interested him. He is known for his massive and continuous correspondence, always asking pertinent questions of those studying what we should ... There is no doubt that some people have the knack of designing simple experi- ments that minimize the number of alternative explanations for the results. Darwin was one of those. For...

Ngày tải lên: 06/08/2014, 18:21

... structures are more stable. Therefore, the obvious candidates for specific pharmacological chaperones for enzyme-related diseases are enzyme inhibitors. Wait a minute! How can an inhibitor, which by ... clinical trials, including drugs for transthyretin-based amyloidosis [20-22], the imino sugar isofagomine for Gaucher disease [23-25], and 1-deoxygalactonojirimycin for Anders...

Ngày tải lên: 06/08/2014, 19:21

... The requirement for genotyping large numbers of markers in large numbers of individuals has meant that, until recently, most association-mapping studies have been for a candidate gene or candidate ... markers and QTL alleles in random-mating populations. Recombination can be increased in linkage-mapping designs by random mating of F 2 or backcross populations for several generations (...

Ngày tải lên: 06/08/2014, 19:20

... lin-26 mutants you don’t get Pn.p cells, while in lin-39 single mutants you don’t get VPC cells and in let-23 mutants you don’t get vulval cells. In lin-26 + lin-39 double-mutants you don’t get Pn.p ... upstream of, lin-39; similarly, in lin-39 + let-23 double mutants you don’t get VPC cells, so lin- 39 is epistatic to, and upstream of, let- 23. In a formal sense, this cell fate pathway is si...

Ngày tải lên: 06/08/2014, 19:20

... activity. For example, core PCP proteins are asymmetrically localized in the Drosophila wing several hours before wing hair formation, and polarized movement of vesicles containing Frizzled can ... Frizzled expression or activity, and the obvious candidates for generating such a gradient, the Wnt ligands, do not appear to be required for planar polarity in Drosophila. Question...

Ngày tải lên: 06/08/2014, 19:21

... medium induced death in the MYC-transformed cells but not the untrans- formed parental cells (Figure 3c). These observations suggested that MYC-transformed cells cannot undergo adipogenic differentiation ... DNA was amplified using primers specific for MYC exon 2 and exon 3, respectively. The expected PCR fragment size for the endogenous MYC gene was1.7 kb and for the transfected MYC cD...

Ngày tải lên: 18/06/2014, 19:20

... preferred position of a dolphin calf beside its mother, and (b,c) water movements near a dolphin when it is (b) gliding passively forward and (c) swimming actively. (a) (b) (c) dolphin mother-calf ... of the downward-moving air, are trailing vortices (Figure 2b). When birds fly in formation, with each bird’s wing tip behind its neighbor’s wing tip, the leader’s trailing vortex may be cancelle...

Ngày tải lên: 06/08/2014, 18:21

... two parts for training and the left part for testing. For each method, this procedure was repeated for 100 times, and the averages and stan- dard deviations of accuracy were taken for performance evaluation. Results Similar ... betwe en ANMM and CBR, and therefore the performance of CBR classification can be improved by ANMM feature selection. Using ANMM for feature selection an...

Ngày tải lên: 12/08/2014, 17:20

... Central Page 1 of 7 (page number not for citation purposes) Human Resources for Health Open Access Methodology Developing a competency-based curriculum in HIV for nursing schools in Haiti Elisa ... compe- tencies to define what is taught in the pre-service arena can achieve the following: provide clarity of learning direction for both faculty and students, set the framework for...

Ngày tải lên: 18/06/2014, 17:20