Báo cáo sinh học: "Q&A: Quantitative approaches to planar polarity and tissue organization" pot
Báo cáo sinh học: "Q&A: Quantitative approaches to planar polarity and tissue organization" pot
...
molecular and mechanical demands on the tissue?
Another open question is how the core PCP proteins are
able to mediate the wide range of cell behaviors associated
with planar polarity. Planar polarity ... display
two types of polarity: apical-basal polarity and planar cell
polarity (PCP; also called tissue polarity) . Apical-basal
polarity refers to the asymme...
Báo cáo sinh học : "Q&A: Genetic analysis of quantitative traits" pdf
... this method is limited to
QTL alleles with large effects and to
organisms amenable to the
experimental generation of tens of
thousands of recombinants.
Otherwise, we need to seek
corroborating ... markers and quantitative
phenotypic variation will provide a
biological context in which to
interpret the phenotype. Finally,
quantitative traits do not exist in a
vacuum, but are...
Báo cáo sinh học: " Q&A: What did Charles Darwin prove" ppsx
... was also a great natural
historian himself, so his own obser-
vations pervade his writings. He was
then able to integrate observations
from one species into a prototype for
what we now call the ... deal
of developing and applying new
statistical methods, but Darwin was
on to the problem. He just did not use
statistics and probabilities, which is
why I call his method a prototype. For...
Báo cáo sinh học : "Q&A: Epistasis" pot
... the torso pathway as
an example, the remarkable thing is that
the pathway was figured out using
genetic experiments before either gene
was cloned and found to be in the one
case a receptor and ... factor. Genetic and molecular
experiments complement each other: if
only molecular biology were available,
there would have been no way of
linking the receptor and the trans-
cription fact...
Báo cáo sinh học: "Q&A: What are pharmacological chaperones and why are they interesting" pdf
... known to attenuate
ER stress [19], improve glucose tolerance and insulin
action in a mouse model of type 2 diabetes. These findings
offer a potential new approach to improve insulin action
and ... shown to be safe, and in some cases to have a
therapeutic effect in humans.
Do pharmacological chaperones have wider
potential?
The answer appears to be yes. Although most of th...
Báo cáo sinh học: "Q&A: What can microfluidics do for stem-cell research" ppsx
... cells align in random fashion,
and although matrix coatings on tissue- culture plastic
can be used to line cells up relative to the matrix, it is
impossible to present signals to separate subcellular ... and
differentiation can be defined quantitatively and in high
throughput. Control over the culture environment also
allows investigators to perturb cell fate to generate...
Báo cáo sinh học: " Periostin: a promising target of therapeutical intervention for prostate cancer" potx
... contributions
CS and XZ carried out the studies and were co-first author. GX and QD
participated in the design of the study. KX helped to draft the manuscript.
JG and WL helped to finish the studies. WD and ... Immunohistochemical
staining of periostin in PCa and BPH. Negative epithelial and stromal
periostin expression in BPH(a) and PCa(c). Positive epithelial and strom...
Báo cáo sinh học: "Hitching a lift hydrodynamically - in swimming, flying and cycling" ppsx
... them, dolphin calves might be unable
to keep up with the adults if they did not keep close to their
mothers.
A different hydrodynamic effect enables dolphins to save
energy by exploiting the water ... energy than a solitary rider, and a rider
behind a pack of eight cyclists used 39% less energy than
when cycling alone. Thus, it is unwise to take the lead in a
race too early [9].
The...
Báo cáo khoa học: Adenine, a hairpin ribozyme cofactor – high-pressure and competition studies potx
... when the two cofactors were added
together. This indicates that both adenine and Mg
2+
must be present for the reaction to occur, and that the
order of addition of the two cofactors does not signifi-
cantly ... thiol, and functional amino and carboxylate
groups [11–13]. Another way for RNA to increase its
chemical diversity would be to bind exogenous mole-
cules carrying reactive...
Báo cáo khoa học: "Bootstrapping a Unified Model of Lexical and Phonetic Acquisition" potx
... pages 111–120, Stockholm.
Stockholm University.
Sharon Goldwater, Tom Griffiths, and Mark Johnson.
2006. Interpolating between types and tokens by esti-
mating power-law generators. In Advances ... phone is likely to share articulatory features
with the intended phone) and use a bootstrapping
process to iteratively infer the intended forms and
retrain the language model and noise...