Báo cáo sinh học: "The ‘stem cell’ concept: is it holding us

Báo cáo sinh học: "The ‘stem cell’ concept: is it holding us back" pptx

... reconstitution. These and other studies gave us a good and enduring operational definition for stem cells: those cells that when introduced Opinion The ‘stem cell’ concept: is it holding us back? Arthur ... burning - but it happens that no substance with definite physical charac- teristics has ever been found that satisfies this operational definition. Indeed, it was...

Ngày tải lên : 06/08/2014, 19:21

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Báo cáo sinh học: "Cancer stem cell subsets and their relationship" pot

... to the development of the concept, literature review, discussions, and writing of the manuscript. All authors have read the manuscript and agree to its submission. Conflicts of interests The authors ... primary pituitary adenoma. Besides these capacities, pituitary adenoma stem cells could form tumors in the continuous xenotransplanation assays. This was the first experimental evidence of the...

Ngày tải lên : 18/06/2014, 19:20

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Báo cáo toán học: "The t-pebbling number is eventually linear in t " pptx

... (1) for all t. To this end, we consider the distribution p 0 with r x t − 1 pebbles, all placed at a vertex y with mdist(x, y) = r x . We claim that, starting with p 0 , it is impossible to obtain t ... check this, we deﬁne the potential of a pebbling distribution p as F (p) :=  v∈V (G) p(v) mdist(v, x) . It is easy to see that this potential is nonincreasing under pebbling moves (...

Ngày tải lên : 08/08/2014, 14:23

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Báo cáo sinh học: " The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single human T-cell" docx

... Lane 3 is K1, Lane 4 is K2, Lane 5 is K3, and Lane 6 is K4. The positive bands are 650 base pairs in size. F. HIV-1. Lane 1 is a 100 bp ladder (Invitrogen). Lane 2 is K6 and Lane 3 is K7. ... Lane 1 is the ladder. Lane 2 is K5, Lane 4 is K7. The positive bands are 269 base pairs in size. D. HCV. Lane 1 is the ladder. Lane 3 is K6. E. HIV-1. Lane 1 is the ladder...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: " The herpes simplex virus UL20 protein functions in glycoprotein K (gK) intracellular transport and virus-induced cell fusion are independent of UL20 functions in cytoplasmic virion envelopment" docx

... mutant allowed some virus- induced cell fusion caused by either the gBsyn3 or gKsyn1 mutation suggesting that the requirement of this residue for infectious virus production is more stringent that ... to inhibit virion production, but allowed some cell fusion to occur. As is the case with the carboxyl terminus of UL20p dis- cussed earlier, these results suggest that the amino terminus o...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: "The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" pdf

... using an annexin V- FITC assay) was used as an index of apoptotic (annexin- positive) versus necrotic (PI positive) cell death [28] (Figure 2). This approach enables simultaneous estima- tion of ... respec- tively,P<0.05).Therefore,efficientactivationofapop- tosis following 5-FU treatment may be associated with cellular reliance on mitochondrial energetic metabolism for cellular energy pro...

Ngày tải lên : 18/06/2014, 19:20

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Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt

... (Figure 7). Discussion Ischemic heart disease, a maj or cause of mortali ty in developed countries, is characterized by interrupted blood s upply to the myocardium that leads to tissue necrosis. The ... myocardial ischemia-reperfusion-induced injury. In addition, myocardial infarction area is correlated with the exercise tolerance capability. The smaller the infarction area, the better qu...

Ngày tải lên : 18/06/2014, 19:20

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Báo cáo sinh học: "The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance" doc

... MIM, oesophageal squamous cell carcinoma, metastasis Background Tumour metastasis is the most significant contributor to the mortality of patients with cancers. Metastasis of cancer cells proceeds ... and suppressors of metastasis. Metastasis suppressor genes are defined by their ability to inhibit metastasis at any step of the metastatic cascade. To date, only a limited number of metasta...

Ngày tải lên : 18/06/2014, 19:20

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Báo cáo sinh học: "The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling" potx

... longevity phenotype of IGF-1R-deficient mice is associated with enhanced resistance to oxidative stress [3]. It is likely that this phenomenon is due to hyperactivation of FOXO proteins, as ... subsequent phenotypic and epistasis analyses with these two lines. Because FOXO transcription factors have been proposed to be the primary effectors of insulin signaling, on the basis of epi...

Ngày tải lên : 06/08/2014, 18:20

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Báo cáo sinh học: "The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal" pot

... used for genotyping. Ptdsr -/- embryos and their wild-type littermates were used for experiments. Histology, TUNEL staining and immunohistochemistry Embryos for histology and immunohistochemistry ... and skin, with moderate to low expression in lung, small intestine, spleen, stomach and skeletal muscle. Thus, Ptdsr is ubiqui- tously expressed throughout embryogenesis and in adult tissues, a...

Ngày tải lên : 06/08/2014, 18:21

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