Báo cáo sinh học: " NFIX - one gene, two knockouts, multiple effects" pdf

Báo cáo sinh học: " NFIX - one gene, two knockouts, multiple effects" pdf

Báo cáo sinh học: " NFIX - one gene, two knockouts, multiple effects" pdf

... acceptor 1a/1b 3 5′ splice acceptor 1a/1b 3 loxP X-NY X-Freiburg NFIA NFIB-NY NFIC NFI wild-type allele 1a/1b PGK-neo 3 LacZ 1a/1b 3 NFIB-Freiburg LacZ-neo 1a/1b 3 1a/1b PGK-neo 3 Transcript 1 2 3 1 21 3 + 1 ... 77:: 29 (P) 2 1-2 8. The X-NY strain, on the other hand, did not suffer from such severe impairments. Callosal agenesis as seen in the X-Freiburg strain was not noted in X-NY NF...
Ngày tải lên : 06/08/2014, 18:21
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Báo cáo sinh học: "Influenza: one or two more questions" pdf

Báo cáo sinh học: "Influenza: one or two more questions" pdf

... the oil-and-water emulsions that may be deployed in influenza vaccines, once solved, will answer some important outstanding questions about how innate immune responses fine-tune adaptive ones. Miranda ... vaccines include oil-in- water emulsions; we do not know how they work either. It is known that distinct types of pathogen tend to evoke distinct kinds of adaptive immune response - both...
Ngày tải lên : 06/08/2014, 19:20
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Báo cáo sinh học: " Genome comparison of two Coccolithoviruses" doc

Báo cáo sinh học: " Genome comparison of two Coccolithoviruses" doc

... PSI-BLAST searches reveal no significant matches. However, PSI-BLAST searches reveal strong matches for KELCH-like proteins (e -5 0 ) after only two rounds for the EhV-163 version of ehv142. PSI-BLAST searches ... EhV-163 has provided a wealth of information which will aid the re-annotating of parts of the EhV-86 genome and identi- fied an intriguing gene replacement and a highly diver-...
Ngày tải lên : 19/06/2014, 08:20
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Báo cáo sinh học: "Sometimes one just isn’t enough: do vertebrates contain an H2A.Z hyper-variant" docx

Báo cáo sinh học: "Sometimes one just isn’t enough: do vertebrates contain an H2A.Z hyper-variant" docx

... H2A.Z-1 and H2A.Z-2 isoforms in vertebrates. BMC Biol 2009, 7:86. 12. Eirín-López JM, González-Romero R, Dryhurst D, Ishibashi T, Ausió J: The evolutionary diff erentiation of two histone H2A.Z ... have multiple H2A.Z isoforms.  ree have been reported in A. thaliana - HTA8, HTA9 and HTA11 - which share about 90% identity but have distinct expression patterns, with HTA9 alone...
Ngày tải lên : 06/08/2014, 19:21
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Báo cáo sinh học: "The Sturm-Liouville BVP in Banach space" pdf

Báo cáo sinh học: "The Sturm-Liouville BVP in Banach space" pdf

... differential equation. Appl. Anal. 59, 225–231 (1995) 2. Schroder, J: Fourth-order two- point boundary value problems: estimates by two side boun ds. Nonlinear Anal. 8, 107–144 (1984) 3. Agarwal, RP, ... 2011, 2011:65 doi:10.1186/168 7-1 84 7-2 01 1-6 5 Su Hua H. Su (jnsuhua@163.com) Lishan Liu L. Liu (lls@mail.qfnu.edu.cn) Xinjun Wang X. Wang (wangxj566@sina.com) ISSN 168 7-1 847 A...
Ngày tải lên : 18/06/2014, 22:20
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báo cáo hóa học: " Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein b" potx

báo cáo hóa học: " Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein b" potx

... in C/EBPb -/ - mixed glial cultures. Expression of pro-inflammatory (NOS2, IL- 1b,IL-6 and TNFa) and anti-inflammatory (IL-4 and TGFb1) genes in C/EBPb +/+ (white bars) and C/EBPb -/ - (black bars) ... glial cultures from the cerebral cortex of one sing le E19-E20 mouse embryo (see Methods for details). Forty -one C/ EBPb-null mice and forty -one wild-type littermates were Table...
Ngày tải lên : 19/06/2014, 22:20
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Báo cáo sinh học: " The eleven-year switch of peptide aptamers" pdf

Báo cáo sinh học: " The eleven-year switch of peptide aptamers" pdf

... constrained com- binatorial proteins (such as antibodies, antibody fragments and other non-antibody scaffold-based molecules) include their small size, their simple design and their disulfide- independent ... (accessible to drug-like small molecules), the cognate peptide aptamer can be used like a ‘cross-hair’ in a high-throughput screening assay to identify small molecules that disrupt the t...
Ngày tải lên : 06/08/2014, 18:21
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Báo cáo sinh học: " Lateral inhibition and concentration-invariant odor perception" pdf

Báo cáo sinh học: " Lateral inhibition and concentration-invariant odor perception" pdf

... line indicating potential projection neuron response in normal larvae. 9 x 10 -4 9 x 10 -3 9 x 10 -2 9 x 10 -1 9 10 -5 10 -4 10 -3 10 -2 10 -1 Test spot luminance (cd/m 2 ) Odor concentration 0 10 20 30 Calcium ... wild-type Or83b in the Or83b mutant background generates larvae with just one functional ORN type, which they term OrX-functional. These Or83b...
Ngày tải lên : 06/08/2014, 18:21
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Báo cáo sinh học : "Q&A: Genetic analysis of quantitative traits" pdf

Báo cáo sinh học : "Q&A: Genetic analysis of quantitative traits" pdf

... QTL alleles in random-mating populations. Recombination can be increased in linkage-mapping designs by random mating of F 2 or backcross populations for several generations (so-called advanced intercross ... genomic region containing one or more candidate genes affecting the trait. Determining which one( s) are causal is the next step. The most straightforward method is high- resolution re...
Ngày tải lên : 06/08/2014, 19:20
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Báo cáo sinh học : "The genetics of gender and life span" pdf

Báo cáo sinh học : "The genetics of gender and life span" pdf

... affect life span tend to have a greater effect in one sex than the other [1,2]. For example, reduced insulin/insulin-like growth factor 1 (IGF-1) signaling and dietary restriction tend to increase ... often sex-specific or sex-biased in Drosophila, mice and humans, and studies over the past few years show strikingly different effects of inbreeding in male versus female insects [4,5]. Two...
Ngày tải lên : 06/08/2014, 19:20
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