Báo cáo sinh học: "Stage debut for the elusive Drosophila insulin-like growth factor binding proteins" potx
Báo cáo sinh học: "Stage debut for the elusive Drosophila insulin-like growth factor binding proteins" potx
... into the mechanisms and effects of IIS.However, an important aspect of the extracellular regulationof the pathway has not been dissected in Drosophila: the binding of ligands by extracellular binding ... activates the extra-cellular signal-regulated kinase (Erk), and the Akt branch of the pathway interacts with the target of rapamycin (TOR)pathway [5].Although there are numerous variants of the ... Furthermore, it may be interesting todetermine whether Imp-L2, like some IGFBPs, has functionsindependent of Dilp binding, opening up the possibility ofusing Drosophila to understand how these...
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Báo cáo sinh học: " Some results for the q-Bernoulli, q-Euler numbers and polynomials" ppt
... completes the proof. Remark 3.2. The remarkable point is that the series on the right-hand side ofLemma 3.1 is uniformly convergent in the wider sense.From (2.13)and (2.14), we define the q-Bernoulli ... Cpdenote the ring of p-adic integers, the fieldof p-adic numbers, and the completion of the algebraic closure of Qp, respectively.Let | · |pbe the p-adic norm on Q with |p|p= p−1. For convenience, ... 0 and log is the p-adic logarithm. Note that in (2.10), the term withi = 0 is understood to be 1/log q (the limiting value of the summand in the limiti → 0).We now move on to the p-adic q-Bernoulli...
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Báo cáo sinh học: "Phylogenetic evidence for the distinction of Saaremaa and Dobrava hantaviruses" pot
... participated in the analysis of the results and drafted the manuscript. AV participated in the analysis of the results and helped to draft the manu-script. AP designed the study, participated in the analysisof ... set [22,23]. The test for molecular clock and esti-mation of the time of split of these two viruses was donewith TreePuzzle [21].Competing interests The author(s) declare that they have no ... of negative polarity [1]. The large (L) segmentencodes the viral RNA polymerase, the medium (M) seg-ment the two surface glycoproteins, and the small (S) seg-ment the nucleocapsid protein (N)....
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Báo cáo sinh học: "Optimal design for the detection of a major gene segregation in crosses" potx
... In the Cl cases, the backcrosseswere not produced and the segregation of the major gene was visible only in the F2. In the C2 cases, the F2 was absent and the 2 ... situation, the difference between distribution components means of the global F2 distribution was twice as a high as the difference in either the BC1or the BC2.When a hypothesis ... linear part, the slope (ie the gain in power the number of F2s to the number of F2 + backcross individuals, for the 3 situationsconsidered with respect to the t parameter:...
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Báo cáo sinh học: "Polynomial algorithms for the Maximal Pairing Problem: efficient phylogenetic targeting on arbitrary trees" docx
... optimal path-system for each of the subtrees “hanging off” πxy. In other words,we need optimal path-systems for the subtrees rooted at the verticesuxanduy for u Î πxy. These can beobtained ... containedentirely within the subtree T[vl]. Since these contribu-tions are independent of each other, they are obtainedby solving the MPP on T[vl], i.e., their contribution to the total score of ... equals the sum of the weights of the path-systems that correspond to the edges of the auxiliarygraphs. In order to facilitate backtracing, we keeptabulated not only the weights but also the corre-sponding...
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Báo cáo sinh học: "Evaluating antibiotics for use in medicine using a poloxamer biofilm model" potx
... between the two different growth media. It was found that therewas a significant difference [P < 0.05] between the growth diameters of the zones of inhibition on MH agar andpoloxamer gel. The ... Plateswere left for 5 minutes before excess fluid was removedusing a sterile pipette. Sterile forceps were used to place the antimicrobial discs on the plates. The antimicrobialdiscs were then placed ... meropenemwas the most effective antibiotic against the poloxamer gelgrown form of the bacterium producing a 26.87 mmmean zone of inhibition. Not only was there a differencein the extent of...
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Báo cáo sinh học: "Fast calculation of the quartet distance between trees of arbitrary degrees" potx
... the first graph in Fig. 3, which shows that the plot of the polynomial n3 (representing the best sum-of-squares fit of the polynomial c·n3 to the data-points) isclosest to the plot of the ... the existing O(n2d2) and O(n3) time algorithms for random and r8s trees. The lines are fitted polynomial c. n2, for the case of the new algorithm (denoted n2d in the legend) and the ... id' are not independent,therefore we have investigated how the structure of the trees affect the running time of the algorithm. We showthat the time used to count the butterfly quartets – topol-ogies...
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Tài liệu Báo cáo Y học: Solution structure of the mEGF/TGFa44250 chimeric growth factor doc
... growth factor/ transforming growth factor a tail chimera with the human epidermal growth Table 4. Optimal hydrogen bonds in the family of chimerastructures, found using the programWHAT-IF [56]. The ... 3. The difference between the backbone of the chimera and the EGF structure is no greater than thatfound for all the EGF structures, leading to the conclusionthat the increased activity of the ... of other EGF structures, it isunlikely that the low affinity of the chimera for binding to the majority of cell surface EGFRs [18] results fromgross structural changes in the unbound growth factor. ...
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Báo cáo sinh học: "Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety" ppt
... over the course of three hours, with a stepwiseincrease in dose rate (10% of the total dose over the first 60 min, 30% over the next 60 min, and 60% over the last 60 min) through the catheter ... Tsubouchi1,2AbstractBackground: Hepatocyte growth factor (HGF) stimulates hepatocyte proliferation, and also acts as an anti-apoptotic factor. Therefore, HGF is a potential therapeutic agent for treatment of fatal ... useful in guidingprognosis: the time to onset of encephalopathy is nega-tively correlated with outcome. The only effective ther-apy for FH is liver transplantation. Other therapies,including corticosteroids,...
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báo cáo sinh học:" Human resources for health planning and management in the Eastern Mediterranean region: facts, gaps and forward thinking for research and policy" pot
... represent HRH mainly because they account for the majority of care providers in most countries [7].Another reason for not using the other categories of healthworkers is the large percentage of missing ... on whether such findings hold for LMICs and MHICs. Therefore, we split the global data intoLMICs and MHICs and carried out the same analysis sep-arately for each of those income groups. The importanceof ... integralcomponent of their health reform programs.Achieving the MDG will not occur unless there is a rightmix of health workforce with the right skills in the rightplace at the right time. This...
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